Tag: M.W=50-100

Purkhosrow, Azar published the artcileHighly efficient, one pot, solvent and catalyst, free synthesis of novel quinazoline derivatives under ultrasonic irradiation and their vasorelaxant activity isolated thoracic aorta of rat, Formula: C2H6N2O, the main research area is quinazoline preparation green chem ultrasonic irradiation vasorelaxant thoracic aorta; One pot; Quinazoline; Thoracic aorta of rat; Ultrasonic irradiation; Vasorelaxant activity.

New quinazoline derivatives I (R = Ph, 4-methylpiperazin-1-yl, 3-hydroxypyridin-2-yl, N-methylcarbamoyl, etc.) were prepared by one pot reaction of anthranilic acid, acetic anhydride and primary amines RNH2 under ultrasonic irradiation As a result, ultrasonic irradiation has led to affordable, clean synthesis of a variety of target compounds in much higher yields, than traditional methods. This method has numerous advantages: higher yields, shorter reactions time, and easier work-up. Several structural classes among these compounds were identified to have vasorelaxant activity. In this respect, all of the newly synthesized quinazolinone derivatives I displayed vasorelaxant properties on the isolated thoracic rat aorta. The IC50 of compounds I (R = Ph) (-6.00 ± 0.55), I (R = 4-nitrophenylamino) (-7.31 ± 0.94), I (R = 2,4-dinitrophenylamino) (-7.15 ± 0.81) and I (R = (diphenylmethylidene)aminyl) (-7.77 ± 0.31) was comparable to that seen in the acetylcholine (-7.13 ± 0.14).

Iranian Journal of Pharmaceutical Research published new progress about Green chemistry. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Formula: C2H6N2O.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zhang, Yan published the artcileCharacterization of liquefied products from corn stalk in the presence of polyhydric alcohols with acid catalysis, Product Details of C2H6N2O, the main research area is polyhydric alc acid catalysis liquefied product corn stalk.

Atm. liquefaction technol. has been used widely and is an effective way of biomass component utilization. In this paper, the liquefied products obtained from corn stalk using polyhydric alcs. 1,2-propanediol (PG) mixed diethylene glycol (DEG) through acid catalysis under atm. pressure were characterized by various anal. technologies. The results indicated that 39 kinds of organic compounds were present in bio-oil, among which alcs. were the most, phenols were the second, and their relative contents were 70.7% and 25.6%, resp. There were also some organic acids, ethers, esters, and ketones. More than 80% of these compounds had a carbon number less than 25. Carbon NMR spectra (13C-NMR) showed that different chem. shifts δ (ppm) corresponded to various carbon types. The chem. composition of the residue from liquefaction was complex and contained a certain amount of large mol. substances that were difficult to degrade. It required more severe pyrolysis conditions than those of corn stalk. Results from X-Ray Diffraction (XRD) indicated the destruction of crystalline structure of carbohydrates and the cellulose mols. were cracked, indicating that the cellulose was degraded and the degree of liquefaction was high.

BioResources published new progress about Acid catalysis. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Product Details of C2H6N2O.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Egorov, Gennadiy I. published the artcileVolumetric properties (water + 1,3-dimethylurea) mixture over the temperature range from 274.15 to 333.15 K at the ambient pressure – comparison with other methyl substituted analogues, Product Details of C2H6N2O, the main research area is methyl water dimethylurea mixture temperature ambient pressure.

Measurements of the binary mixture {water (1) + 1,3-dimethylurea (2)} d. within the temperature range of 274.15 to 333.15 K were performed within a wide range of compositions at the atm. pressure by using the d. gauge with a U-shaped vibrating tube. There are calculated apparent and partial molar volumes of water and 1,3-dimethylurea (1,3-DMU) in the mixture, limiting (standard) partial molar volumes of 1,3-DMU in water, molar isobaric thermal expansion of the mixture and molar isobaric thermal expansion of 1,3-DMU at infinite dilution It is shown that concentration dependences of partial molar volumes of the water and 1,3-DMU are characterized by the presence of extremums thus revealing manifestation of hydrophobic nature of the 1,3-dimethylurea mol. Limiting partial molar volumes of 1,3-DMU increase with the increase of the temperature Increasing both the temperature and the concentration of 1,3-DMU lids to the increasing of the molar isobaric expansion of the mixture The obtained results are discussed in terms of the solute – solvent and solute – solute interactions. A comparison of the obtained characteristics with similar characteristics of the urea, N-methylurea and tetramethylurea is performed.

Journal of Molecular Liquids published new progress about Binary mixtures. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Product Details of C2H6N2O.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Suriyanarayanan, Subramanian published the artcileNon-ionic deep eutectic liquids: acetamide-urea derived room temperature solvents, Category: isoquinoline, the main research area is acetamide urea room temperature solvent deep eutectic liquid; acetamide–urea; deep-eutectic solvent; flickering cluster.

A family of non-ionic deep eutectic liquids has been developed based upon mixtures of solid N-alkyl derivatives of urea and acetamide that in some cases have m.ps. below room temperature The eutectic behavior and phys. characteristics of a series of eleven eutectic mixtures are presented, along with a mol. dynamics study-supported hypothesis for the origin of the non-ideal mixing of these substances. Their use as solvents in applications ranging from natural product extraction to organic and polymer synthesis are demonstrated.

International Journal of Molecular Sciences published new progress about Click chemistry. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Liu, Mingsheng published the artcileAn efficient anti-flaming phosphorus-containing guanazole derivative for cotton fabric, Category: isoquinoline, the main research area is guanazole flaming phosphorus cotton fabric.

A high-efficiency, halogen-free flame retardant: ammonium salt of guanazole-penta-(methylphosphonic acid) (AGPMPA) was synthesized in water solution under a mild reaction condition. The chem. structure of AGPMPA was characterized by FT-IR, 1H NMR, 13C NMR and 31P NMR spectra. Vertical burning tests showed that cotton fabrics treated with 20%, 25% and 30% AGPMPA cannot be ignited, and the shortest carbon length reaches 2.9 cm for 30% treated cotton. The limiting oxygen indexes of the treated cottons go up to 43.7-47.9% with the increases of AGPMPA concentrations and are still beyond 26.8% even after 50 laundering cycles, indicating that AGPMPA is a superior, durable flame retardant. Simultaneously, cone calorimeter data indicate that the heat release rate and the total heat release of treated cotton was remarkably decreased compared with those of control cotton. The TG-IR results indicate that the amounts of volatile products are prominently reduced, and the degradation temperature of treated cotton is lower than that of control cotton. The residual amounts of 46.1% in N2 gas and 31.6% in air for treated cotton fabric were attained, resp. No noteworthy change for the surface of treated cotton fiber was observed by SEM. The mech. properties of cotton fabrics before and after treatment have barely changed. These results proved that eco-friendly AGPMPA is an effective anti-flaming agent and has excellent durability.

Cellulose (Dordrecht, Netherlands) published new progress about Cotton textiles. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Liu, Mingsheng published the artcileAn efficient anti-flaming phosphorus-containing guanazole derivative for cotton fabric, Product Details of C2H5N5, the main research area is guanazole flaming phosphorus cotton fabric.

A high-efficiency, halogen-free flame retardant: ammonium salt of guanazole-penta-(methylphosphonic acid) (AGPMPA) was synthesized in water solution under a mild reaction condition. The chem. structure of AGPMPA was characterized by FT-IR, 1H NMR, 13C NMR and 31P NMR spectra. Vertical burning tests showed that cotton fabrics treated with 20%, 25% and 30% AGPMPA cannot be ignited, and the shortest carbon length reaches 2.9 cm for 30% treated cotton. The limiting oxygen indexes of the treated cottons go up to 43.7-47.9% with the increases of AGPMPA concentrations and are still beyond 26.8% even after 50 laundering cycles, indicating that AGPMPA is a superior, durable flame retardant. Simultaneously, cone calorimeter data indicate that the heat release rate and the total heat release of treated cotton was remarkably decreased compared with those of control cotton. The TG-IR results indicate that the amounts of volatile products are prominently reduced, and the degradation temperature of treated cotton is lower than that of control cotton. The residual amounts of 46.1% in N2 gas and 31.6% in air for treated cotton fabric were attained, resp. No noteworthy change for the surface of treated cotton fiber was observed by SEM. The mech. properties of cotton fabrics before and after treatment have barely changed. These results proved that eco-friendly AGPMPA is an effective anti-flaming agent and has excellent durability.

Cellulose (Dordrecht, Netherlands) published new progress about Cotton textiles. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Product Details of C2H5N5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wu, Le published the artcileSynthesis of 3,5-ditetrazolyl-1,2,4-triazole-based complexes: a strategy for developing C-N-linked triheterocyclic energetic compound, Synthetic Route of 1455-77-2, the main research area is explosive cyclic zolyl zole complex synthesis.

A novel C-N-linked triheterocyclic compound, 3,5-ditetrazolyl-1,2,4-triazole (DTT), was synthesized via a facile strategy from 3,5-diamino-1,2,4-triazole. Two metal complexes based on the DTT ligand were prepared and fully characterized using elemental anal., IR spectroscopy, mass spectrometry, and single-crystal X-ray diffraction. Their properties, including d., heat of formation, thermal stability and sensitivity, as well as detonation performance determined using the EXPLO5 program package, were investigated. NaDTT and KDTT showed high pos. heats of formation, low sensitivities and good detonation performances. The approach presented here could contribute to the development of C-N-linked polyheterocyclic compounds as new energetic materials.

New Journal of Chemistry published new progress about Crystallography. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wu, Le published the artcileSynthesis of 3,5-ditetrazolyl-1,2,4-triazole-based complexes: a strategy for developing C-N-linked triheterocyclic energetic compound, Synthetic Route of 1455-77-2, the main research area is explosive cyclic zolyl zole complex synthesis.

A novel C-N-linked triheterocyclic compound, 3,5-ditetrazolyl-1,2,4-triazole (DTT), was synthesized via a facile strategy from 3,5-diamino-1,2,4-triazole. Two metal complexes based on the DTT ligand were prepared and fully characterized using elemental anal., IR spectroscopy, mass spectrometry, and single-crystal X-ray diffraction. Their properties, including d., heat of formation, thermal stability and sensitivity, as well as detonation performance determined using the EXPLO5 program package, were investigated. NaDTT and KDTT showed high pos. heats of formation, low sensitivities and good detonation performances. The approach presented here could contribute to the development of C-N-linked polyheterocyclic compounds as new energetic materials.

New Journal of Chemistry published new progress about Crystallography. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wang, Hao published the artcileHigh performance epoxy resin composites modified with multifunctional thiophene/phosphaphenanthrene-based flame retardant: Excellent flame retardance, strong mechanical property and high transparency, Synthetic Route of 1455-77-2, the main research area is thiophene phosphaphenanthrene flame retardant epoxy resin composite mech property.

It is always a challenge to prepare multifunctional epoxy resins (EP) composites with excellent flame retardance, mech. property and high transparency. In this work, a reactive flame-retardant (BDO) was synthesized from DOPO, 3,5-diamino-triazolz and thiophene-2-formaldehyde, and taken to prepare EP/BDO composites. Surprisingly, benefitting from the synergy of efficient flame retardant unit (DOPO structure), catalytic curing unit (triazole structure) and optical functional structure (thiophene-2-formaldehyde), the EP composites with excellent comprehensive performance was obtained. In detailed, after adding only 5 wt% BDO, the EP composites passed the UL-94 V-0 level, and the limiting oxygen index was increased to 33% from 22.5% of neat EP. At the same time, EP/BDO-5 showed obvious heat suppression and smoke suppression effects. Besides, EP/BDO-5 presented excellent mech. strength, that the tensile strength and bending strength were increased by 25% and 30% compared with neat EP. Moreover, EP/BDO composites maintained the same good light transmittance as neat EP, and also presented enhanced Tg and dielec. property. In addition, the dual phase flame-retardant mechanism was revealed through systematically analyzing residues after combustion and the gaseous phase products of flame retardant. The above results indicated EP/BDO composites with excellent comprehensive performance possessed a great potential application in high-performance composites fields.

Composites, Part B: Engineering published new progress about Bending strength. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wang, Hao published the artcileHigh performance epoxy resin composites modified with multifunctional thiophene/phosphaphenanthrene-based flame retardant: Excellent flame retardance, strong mechanical property and high transparency, Quality Control of 1455-77-2, the main research area is thiophene phosphaphenanthrene flame retardant epoxy resin composite mech property.

It is always a challenge to prepare multifunctional epoxy resins (EP) composites with excellent flame retardance, mech. property and high transparency. In this work, a reactive flame-retardant (BDO) was synthesized from DOPO, 3,5-diamino-triazolz and thiophene-2-formaldehyde, and taken to prepare EP/BDO composites. Surprisingly, benefitting from the synergy of efficient flame retardant unit (DOPO structure), catalytic curing unit (triazole structure) and optical functional structure (thiophene-2-formaldehyde), the EP composites with excellent comprehensive performance was obtained. In detailed, after adding only 5 wt% BDO, the EP composites passed the UL-94 V-0 level, and the limiting oxygen index was increased to 33% from 22.5% of neat EP. At the same time, EP/BDO-5 showed obvious heat suppression and smoke suppression effects. Besides, EP/BDO-5 presented excellent mech. strength, that the tensile strength and bending strength were increased by 25% and 30% compared with neat EP. Moreover, EP/BDO composites maintained the same good light transmittance as neat EP, and also presented enhanced Tg and dielec. property. In addition, the dual phase flame-retardant mechanism was revealed through systematically analyzing residues after combustion and the gaseous phase products of flame retardant. The above results indicated EP/BDO composites with excellent comprehensive performance possessed a great potential application in high-performance composites fields.

Composites, Part B: Engineering published new progress about Bending strength. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Quality Control of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem