Palladium-Catalyzed Isoquinoline Synthesis by Tandem C-H Allylation and Oxidative Cyclization of Benzylamines with Allyl Acetate was written by Chen, Yujie;Huang, Zhibin;Dai, Chenyang;Yang, Shan;Shi, Da-Qing;Zhao, Yingsheng. And the article was included in Organic Letters in 2021.Recommanded Product: 14446-31-2 This article mentions the following:
A novel approach to synthesize 3-methylisoquinolines via a one-pot, two-step, palladium(II)-catalyzed tandem C-H allylation/intermol. amination and aromatization is reported. A wide series of 3-methylisoquinoline derivatives were obtained directly using this method in moderate to good yields, and authors highlight the synthetic importance of this new transformation. In the experiment, the researchers used many compounds, for example, 6-Methoxy-3-methylisoquinoline (cas: 14446-31-2Recommanded Product: 14446-31-2).
6-Methoxy-3-methylisoquinoline (cas: 14446-31-2) belongs to isoquinoline derivatives. Being an analog of pyridine, isoquinoline is a weak base, with a pKa of 5.14. Most traditional methods of generating isoquinoline do so via oxidative aromatization of dihydro- or tetrahydro-isoquinolines, usually offering some environmental or economic advantage.Recommanded Product: 14446-31-2
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem