Category: 1455-77-2

Nabipour, Hafezeh published the artcileAn environmentally friendly approach to fabricating flame retardant, antibacterial and antifungal cotton fabrics via self-assembly of guanazole-metal complex, Name: 3,5-Diamino-1,2,4-triazole, the main research area is cotton fabric guanazole metal complex flammability antibacterial antifungal property.

Cotton fabrics are prone to ignite fire accidents as well as breed bacteria and fungi, which have hampered their applications in the field of packaging and home decorations. Guanazole complexes with silver and zinc ions were deposited to cotton fabrics through self-assembly to prepare the flame-retardant and antibacterial cotton fabrics. The effect of the guanazole-metal complexes on the morphol. structure, flammability and thermal degradation of cotton fabrics was studied by field emission SEM, limiting oxygen index (LOI), UL-94 vertical burning test, and thermogravimetric anal. The antibacterial and antifungal activities of the coated fabrics were evaluated as well. The guanazole-zinc and guanazole-silver treated cotton fabrics showed a high LOI of 29.5% and 27.5%, resp. In the vertical burning test, both the guanazole-zinc and guanazole-silver treated cotton fabrics self-extinguished when removing the ignition source, displaying a UL-94 V-0 classification, while the untreated one and the guanazole-treated one burned out. Thermogravimetric anal. results confirmed that the guanazole-metal complexes promoted the thermal decomposition of cotton and thus improved the char yield significantly. Micro-scale combustion calorimeter measurements clarified that the guanazole-zinc and guanazole-silver treated cotton displayed dramatically decreased peak heat release rate (64.4% and 59.1%, resp.) and total heat release (26.4% and 14.8%, resp.) in comparison to the untreated one. The significantly improved flame retardancy of guanazole-metal complexes treated cotton fabrics could be attributed to their enhanced charring capability that blocked flammable volatiles into flame zone. The treated cotton fabrics with guanazole-metal complexes exhibited better antibacterial capacity against Staphylococcus aureus and Escherichia coli than the untreated and guanazole-treated ones. Furthermore, the guanazole-silver treated cotton fabrics also showed good antifungal activity against Penicillium, Fusarium chlamydosporum and Aspergillus niger.

Journal of Cleaner Production published new progress about Antibacterial agents. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Name: 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Sumrra, Sajjad Hussain published the artcileComputational investigation of molecular structures, spectroscopic properties, cholinesterase inhibition and antibacterial activities of triazole Schiff bases endowed metal chelates, Name: 3,5-Diamino-1,2,4-triazole, the main research area is triazoldiamine salicylaldehyde derivative electronic structure antibacterial enzyme inhibition activity; transition metal triazole Schiff base preparation antibacterial enzyme inhibition.

The aim of this project was to introduce novel bioactive compounds through the design and synthesis of two mono-Schiff bases, 4- [(5-amino-1H-1,2,4-triazol-3-yl)imino]methylbenzene-1,3-diol (L1) and 2-[(5-amino-1H-1,2,4-triazol-3-yl)imino]methyl-6-methoxyphenol (L2) and one bis-Schiff base, 2,2′-{1H-1,2,4-triazole-3,5-diylbis[nitrilomethylylidene]}bis(6-methoxyphenol) (L3) together with their complexes of transition metals [VO(IV), Cr(III), Mn(II), Fe(II), Co(II), Ni(II), Cu(II), and Zn(II)]. The mol. structures of as-synthesized Schiff bases were explicitly confirmed by phys., spectral, anal. and computational studies. Quantum chem. calculations based on d. functional theory (DFT) were performed at B3LYP/6-311+G(d.p) level to explore the optimized geometrical structures, mol. electrostatic potential (MEP), Mulliken at. charges (MAC) and frontier MO (FMO) anal. of the as-synthesized ligands. The FMO energy gaps were rationalized to be 0.162, 0.158 and 0.138 eV for ligands (L1), (L2) and (L3), resp. which can efficiently polarize their chem. structures. As-synthesized metal complexes have good agreement with their purposed structures with octahedral geometry except V complexes, which have square pyramidal geometry. As-synthesized compounds were also evaluated through TG and fluorescence anal. Addnl., the compounds were also scrutinized for antibacterial activity against five bacterial strains (Halomonas halophila, Chromohalobacter israelensis, Escherichia coli, Chromohalobacter salexigens and Halomonas salina) and enzyme inhibition bioassay against butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). The complexes (15) and (1) were the most active inhibitors of BChE and AChE enzymes with 94.60% and 90.90% activity, resp. Also, all the compounds also exhibited significant antibacterial activity. The metal complexes displayed more biol. activity in contrary to parent ligands as a result of chelation.

Journal of Molecular Structure published new progress about Antibacterial agents. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Name: 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Sumrra, Sajjad Hussain published the artcileComputational investigation of molecular structures, spectroscopic properties, cholinesterase inhibition and antibacterial activities of triazole Schiff bases endowed metal chelates, SDS of cas: 1455-77-2, the main research area is triazoldiamine salicylaldehyde derivative electronic structure antibacterial enzyme inhibition activity; transition metal triazole Schiff base preparation antibacterial enzyme inhibition.

The aim of this project was to introduce novel bioactive compounds through the design and synthesis of two mono-Schiff bases, 4- [(5-amino-1H-1,2,4-triazol-3-yl)imino]methylbenzene-1,3-diol (L1) and 2-[(5-amino-1H-1,2,4-triazol-3-yl)imino]methyl-6-methoxyphenol (L2) and one bis-Schiff base, 2,2′-{1H-1,2,4-triazole-3,5-diylbis[nitrilomethylylidene]}bis(6-methoxyphenol) (L3) together with their complexes of transition metals [VO(IV), Cr(III), Mn(II), Fe(II), Co(II), Ni(II), Cu(II), and Zn(II)]. The mol. structures of as-synthesized Schiff bases were explicitly confirmed by phys., spectral, anal. and computational studies. Quantum chem. calculations based on d. functional theory (DFT) were performed at B3LYP/6-311+G(d.p) level to explore the optimized geometrical structures, mol. electrostatic potential (MEP), Mulliken at. charges (MAC) and frontier MO (FMO) anal. of the as-synthesized ligands. The FMO energy gaps were rationalized to be 0.162, 0.158 and 0.138 eV for ligands (L1), (L2) and (L3), resp. which can efficiently polarize their chem. structures. As-synthesized metal complexes have good agreement with their purposed structures with octahedral geometry except V complexes, which have square pyramidal geometry. As-synthesized compounds were also evaluated through TG and fluorescence anal. Addnl., the compounds were also scrutinized for antibacterial activity against five bacterial strains (Halomonas halophila, Chromohalobacter israelensis, Escherichia coli, Chromohalobacter salexigens and Halomonas salina) and enzyme inhibition bioassay against butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). The complexes (15) and (1) were the most active inhibitors of BChE and AChE enzymes with 94.60% and 90.90% activity, resp. Also, all the compounds also exhibited significant antibacterial activity. The metal complexes displayed more biol. activity in contrary to parent ligands as a result of chelation.

Journal of Molecular Structure published new progress about Antibacterial agents. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, SDS of cas: 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Sumrra, Sajjad H. published the artcileEfficient synthesis, characterization, and in vitro bactericidal studies of unsymmetrically substituted triazole-derived Schiff base ligand and its transition metal complexes, Synthetic Route of 1455-77-2, the main research area is unsym triazole Schiff base ligand transition metal preparation antibacterial; furanylethylideneamino triazolyliminophenol Schiff base preparation transition metal complexation; mol structural calculation furanylethylideneamino triazolyliminophenol Schiff base transition metal.

In the present research, novel unsym. substituted triazole-derived Schiff base ligand 2-[[[5-[[1-(5-methylfuran-2-yl)ethylidene]amino]-1H-1,2,4-triazol-3-yl]imino]methyl]phenol (L) has been synthesized by the reaction of 1,2,4-triazole-3,5-diamine with 2-hydroxybenzaldehyde and with 5-methyl-2-acetylfuran in an equimolar ratio. The synthesized ligand L was characterized by phys. methods (m.p., solubility, color) as well as by spectral techniques (IR, UV-Vis, 1H NMR, 13C NMR, and MS), elemental anal., and computational studies. Computational anal. further elucidated the structure, polarity, stability, and nature of the ligand. The bivalent(II), trivalent(III), and tetravalent(IV) transition metal complexes were formed by reacting Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cr(III) metals as chloride and, VO(IV) as sulfate with Schiff base ligand L in 1:2 (M:L) molar ratio. Ligand was coordinated with the metal ions, VO via benzaldehyde-O and azomethine-N and with Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cr(III) via benzaldehyde-O, azomethine-N, and triazole-N. The structure of the metal complexes was deduced by IR, conductance, magnetic moments, and elemental anal. Biol. evaluation of triazole-derived Schiff base ligand and its metal complexes was carried out against bacterial strains, Escherichia coli, Staphylococcus aureus, Neisseria gonorrhea, and Pseudomonas syringae. Copper complex showed the highest inhibition against all bacterial strains as compared to the free ligand and amongst other metal complexes. In vitro antibacterial studies thus concluded that the prepared ligand showed bioactivity which was enhanced upon chelation/coordination with the metal ions.

Monatshefte fuer Chemie published new progress about Antibacterial agents. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Garcias-Morales, Cesar published the artcileSynthesis and physicochemical characterization of Schiff bases used as optical sensor for metals detection in water, Computed Properties of 1455-77-2, the main research area is synthesis physicochem characterization Schiff base optical sensor metal detection.

In this work, chem. mechanic synthesis of six imines is reported, chem. structure and optical characterization is described. The imines 3a-3f were evaluated as colorimetric chem. sensors of metals: Ba2+, Co2+, Fe2+, Mg2+, Ni2+, Pb2+, Zn2+, Cd2+, Hg2+, Cu2+, Sn2+ and Cs+ where 3e being a highly selective colorimetric chem. sensor for Cu2+. The limit detection of the sensor was determined through the titration, which turned out to be 4.9 x 10-6 M with a Ka of 8.264 x 103 M-1. Also, the interference of detection in a mixture of metals was studied. Finally, by the use of IR, NMR, and DFT calculations, the structure of the 3e + M complex formed, and the phenomenon responsible for the color change was determined Finally, a possible relationship between the selectivity to metal ions and the HOMO energy levels of the mols. is proposed, being a basis for the design of smart organic sensors

Journal of Molecular Structure published new progress about Colorimetric sensors. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Computed Properties of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Peng, Panpan published the artcileSynthesis of energetic salts containing three heterocyclic anions by a one-pot condensation reaction, Application of 3,5-Diamino-1,2,4-triazole, the main research area is energetic salt heterocyclic anion preparation one pot reaction safety.

Heterocyclic energetic salts are extensively used in energetic materials due to their excellent mol. designability. Generally, most inorganic or organic anionic energetic ionic salts contain only one anion or two anions at most. Thus far, energetic ion salts containing three organic energetic anions have not been reported. In this study, we develop a new method for the preparation of energetic ion salts containing three heterocyclic anions via a one-step one-pot condensation reaction. The proposed strategy is based on aldehydes, aminoguanidine salts, and heterocyclic energetic ionic salts. In this work, energetic salt 1 containing three 5-nitrotetrazole anions and energetic salt 2 containing three 3,5-dinitro-1,2,4-triazole anions were successfully synthesized. The results of NMR, IR, and MS proved that the products (1 and 2) contain three heterocyclic anions. The energetic test results indicate that products 1 and 2 have extremely high decomposition temperatures (250 °C and 308 °C) and exhibit low sensitivities (for both 1 and 2, FS > 360 N, IS > 40 J). Meanwhile, their detonation velocities (7306 m s-1 and 7375 m s-1) and detonation pressures (18.3 GPa and 19.7 GPa) are better than those of TNT. This indicates that 1 and 2 have great potential to be applied as heat-resistant insensitive explosives. In addition, the X-ray diffraction results of the non-energetic, p-toluenesulfonic acid anions of product 3 not only further verify the structure of the three heterocyclic anions mentioned above, but also confirm the universality of this method.

New Journal of Chemistry published new progress about Condensation reaction. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Application of 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Peng, Panpan published the artcileSynthesis of energetic salts containing three heterocyclic anions by a one-pot condensation reaction, Formula: C2H5N5, the main research area is energetic salt heterocyclic anion preparation one pot reaction safety.

Heterocyclic energetic salts are extensively used in energetic materials due to their excellent mol. designability. Generally, most inorganic or organic anionic energetic ionic salts contain only one anion or two anions at most. Thus far, energetic ion salts containing three organic energetic anions have not been reported. In this study, we develop a new method for the preparation of energetic ion salts containing three heterocyclic anions via a one-step one-pot condensation reaction. The proposed strategy is based on aldehydes, aminoguanidine salts, and heterocyclic energetic ionic salts. In this work, energetic salt 1 containing three 5-nitrotetrazole anions and energetic salt 2 containing three 3,5-dinitro-1,2,4-triazole anions were successfully synthesized. The results of NMR, IR, and MS proved that the products (1 and 2) contain three heterocyclic anions. The energetic test results indicate that products 1 and 2 have extremely high decomposition temperatures (250 °C and 308 °C) and exhibit low sensitivities (for both 1 and 2, FS > 360 N, IS > 40 J). Meanwhile, their detonation velocities (7306 m s-1 and 7375 m s-1) and detonation pressures (18.3 GPa and 19.7 GPa) are better than those of TNT. This indicates that 1 and 2 have great potential to be applied as heat-resistant insensitive explosives. In addition, the X-ray diffraction results of the non-energetic, p-toluenesulfonic acid anions of product 3 not only further verify the structure of the three heterocyclic anions mentioned above, but also confirm the universality of this method.

New Journal of Chemistry published new progress about Condensation reaction. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Formula: C2H5N5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Peng, Panpan published the artcileSynthesis of energetic salts containing three heterocyclic anions by a one-pot condensation reaction, Application of 3,5-Diamino-1,2,4-triazole, the main research area is energetic salt heterocyclic anion preparation one pot reaction safety.

Heterocyclic energetic salts are extensively used in energetic materials due to their excellent mol. designability. Generally, most inorganic or organic anionic energetic ionic salts contain only one anion or two anions at most. Thus far, energetic ion salts containing three organic energetic anions have not been reported. In this study, we develop a new method for the preparation of energetic ion salts containing three heterocyclic anions via a one-step one-pot condensation reaction. The proposed strategy is based on aldehydes, aminoguanidine salts, and heterocyclic energetic ionic salts. In this work, energetic salt 1 containing three 5-nitrotetrazole anions and energetic salt 2 containing three 3,5-dinitro-1,2,4-triazole anions were successfully synthesized. The results of NMR, IR, and MS proved that the products (1 and 2) contain three heterocyclic anions. The energetic test results indicate that products 1 and 2 have extremely high decomposition temperatures (250 °C and 308 °C) and exhibit low sensitivities (for both 1 and 2, FS > 360 N, IS > 40 J). Meanwhile, their detonation velocities (7306 m s-1 and 7375 m s-1) and detonation pressures (18.3 GPa and 19.7 GPa) are better than those of TNT. This indicates that 1 and 2 have great potential to be applied as heat-resistant insensitive explosives. In addition, the X-ray diffraction results of the non-energetic, p-toluenesulfonic acid anions of product 3 not only further verify the structure of the three heterocyclic anions mentioned above, but also confirm the universality of this method.

New Journal of Chemistry published new progress about Condensation reaction. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Application of 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Peng, Panpan published the artcileSynthesis of energetic salts containing three heterocyclic anions by a one-pot condensation reaction, Formula: C2H5N5, the main research area is energetic salt heterocyclic anion preparation one pot reaction safety.

Heterocyclic energetic salts are extensively used in energetic materials due to their excellent mol. designability. Generally, most inorganic or organic anionic energetic ionic salts contain only one anion or two anions at most. Thus far, energetic ion salts containing three organic energetic anions have not been reported. In this study, we develop a new method for the preparation of energetic ion salts containing three heterocyclic anions via a one-step one-pot condensation reaction. The proposed strategy is based on aldehydes, aminoguanidine salts, and heterocyclic energetic ionic salts. In this work, energetic salt 1 containing three 5-nitrotetrazole anions and energetic salt 2 containing three 3,5-dinitro-1,2,4-triazole anions were successfully synthesized. The results of NMR, IR, and MS proved that the products (1 and 2) contain three heterocyclic anions. The energetic test results indicate that products 1 and 2 have extremely high decomposition temperatures (250 °C and 308 °C) and exhibit low sensitivities (for both 1 and 2, FS > 360 N, IS > 40 J). Meanwhile, their detonation velocities (7306 m s-1 and 7375 m s-1) and detonation pressures (18.3 GPa and 19.7 GPa) are better than those of TNT. This indicates that 1 and 2 have great potential to be applied as heat-resistant insensitive explosives. In addition, the X-ray diffraction results of the non-energetic, p-toluenesulfonic acid anions of product 3 not only further verify the structure of the three heterocyclic anions mentioned above, but also confirm the universality of this method.

New Journal of Chemistry published new progress about Condensation reaction. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Formula: C2H5N5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Li, Ying published the artcileHighly Sensitive Detection of Mercury Ions Using Zincophosphite Framework Nanoparticle-Polyaniline Composites, Category: isoquinoline, the main research area is mercury ions zincophosphite framework nanoparticle polyaniline composite.

This study reports a highly sensitive mercury ion sensor composed of the zincophosphite framework nanoparticle (NTOU4nano) blended with in situ synthesized conductive polyaniline (PANI). High stability of the pristine zincophosphite solid not only renders a facile nanosizing treatment feasible but also allows it to withstand the electrochem. PANI deposition at a low pH condition. PANI significantly enhances the surface coverage concentration and increases the electron transfer capability of the resulting composite. Cyclic voltammetry (CV), differential pulse voltammetry (DPV), hydrodynamic amperometry, and electrochem. impedance spectroscopy (EIS) are used to characterize and optimize the electroanal. performance of the nanocomposite. The resulting electrochem. sensor shows a linear dynamic range for mercury ion detection ranging from 0.05 to 27.5 nM and exhibits one of the lowest limits of detection (LODs) of 3.49 x 10-11 M reported using crystalline organic-inorganic hybrids. Addnl., the practical utility of the nanocomposite for mercury ion sensing is demonstrated using water samples containing high salt concentrations, as well as from the environment including the seawater and river water. In short, the reported nanocomposite is among one of the first metallophosphite materials being consolidated with PANI as an integrated sensing platform for highly sensitive mercury ion detection and holds good promise for early-warning application.

ACS Applied Nano Materials published new progress about Chemically modified electrodes. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem