Category: 21902-40-9

21902-40-9, Name is 1,3-Dichloro-5-methylisoquinoline, belongs to isoquinoline compound, is a common compound. Safety of 1,3-Dichloro-5-methylisoquinolineIn an article, once mentioned the new application about 21902-40-9.

Compounds of the formula SPC1 Wherein R1 is hydrogen, alkyl of 1 to 3 carbon atoms, alkanoyl of 1 to 3 carbon atoms, or alkoxycarbonyl of 2 to 4 carbon atoms, R2 is morpholino, thiomorpholino or 1-oxido-thiomorpholino, and R3 is hydrogen, fluorine, chlorine, bromine, methyl, methoxy or nitro, And non-toxic, pharmacologicaly acceptable acid addition salts thereof; the compounds as well as the salts are useful as anticoagulants.

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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H3720N – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Recommanded Product: 21902-40-9, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 21902-40-9, Name is 1,3-Dichloro-5-methylisoquinoline, molecular formula is C10H7Cl2N

Examples of hydroxymethylated analogues of heteroaryl cores such as quinazolin-4-ones, isoquinolin-1(2H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, chromen-4-ones and pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones are sparse or non-existent in the scientific literature. We have demonstrated that such compounds are accessible by using standard procedures from readily available raw materials.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 21902-40-9, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 21902-40-9, in my other articles.

Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H3721N – PubChem

 

In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Safety of 1,3-Dichloro-5-methylisoquinoline, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 21902-40-9, name is 1,3-Dichloro-5-methylisoquinoline. In an article£¬Which mentioned a new discovery about 21902-40-9

3-Piperazino-isoquinolines and salts thereof

Compounds of the formula SPC1 Wherein R1 is hydrogen, alkyl of 1 to 3 carbon atoms, alkanoyl of 1 to 3 carbon atoms, or alkoxycarbonyl of 2 to 4 carbon atoms, R2 is morpholino, thiomorpholino or 1-oxido-thiomorpholino, and R3 is hydrogen, fluorine, chlorine, bromine, methyl, methoxy or nitro, And non-toxic, pharmacologicaly acceptable acid addition salts thereof; the compounds as well as the salts are useful as anticoagulants.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 21902-40-9, help many people in the next few years.Safety of 1,3-Dichloro-5-methylisoquinoline

Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C10H7Cl2N, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 21902-40-9, Name is 1,3-Dichloro-5-methylisoquinoline, molecular formula is C10H7Cl2N

Synthesis of Novel Hydroxymethyl-Substituted Fused Heterocycles

Examples of hydroxymethylated analogues of heteroaryl cores such as quinazolin-4-ones, isoquinolin-1(2H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, chromen-4-ones and pyrrolo[2,1-f][1,2,4]triazin-4(3H)-ones are sparse or non-existent in the scientific literature. We have demonstrated that such compounds are accessible by using standard procedures from readily available raw materials.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C10H7Cl2N, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 21902-40-9, in my other articles.

Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.21902-40-9,1,3-Dichloro-5-methylisoquinoline,as a common compound, the synthetic route is as follows.

N-Bromosuccinimide (0.77 mL, 9.05 mmol) and AIBN (248 mg, 1.51 mmol) were added portionwise to a suspension of 1,3-dichloro-5-methylisoquinoline (1.60 g, 7.54 mmol) in degassed EtOAc (20 mL) at reflux under a nitrogen atmosphere. The resulting solution was stirred at reflux for 16 hours. The mixture was concentrated to provide an orange solid. The crude product was purified by flash silica chromatography with 40% DCM in heptane as eluent. Pure fractions were evaporated to dryness to afford 5-(bromomethyl)-1,3-dichloroisoquinoline (1.64 g, 75%) as a colourless solid., 21902-40-9

21902-40-9 1,3-Dichloro-5-methylisoquinoline 21518478, aisoquinoline compound, is more and more widely used in various fields.

Reference£º
Article; Holmes, Jane L.; Almeida, Lynsie; Barlaam, Bernard; Croft, Rosemary A.; Dishington, Allan P.; Gingipalli, Laksmaiah; Hassall, Lorraine A.; Hawkins, Janet L.; Ioannidis, Stephanos; Johannes, Jeffrey W.; McGuire, Thomas M.; Moore, Jane E.; Patel, Anil; Pike, Kurt G.; Pontz, Timothy; Wu, Xiaoyun; Wang, Tao; Zhang, Hai-Jun; Zheng, Xiaolan; Synthesis; vol. 48; 8; (2016); p. 1226 – 1234;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem