Category: 566943-98-4

Chen, Ping’s team published research in Bioorganic & Medicinal Chemistry Letters in 2003 | CAS: 566943-98-4

5-Bromoisoquinolin-6-amine(cas: 566943-98-4) belongs to isoquinoline.Computed Properties of C9H7BrN2 Isoquinoline is a structural isomer of quinoline, and quinoline derivatives are fused ring compounds of pyridine and benzene rings, which have antiseptic, antipyretic and anti-cyclic properties, and can be used as antimalarial drugs and for the preparation of other antimalarial medicine.

《Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors》 was written by Chen, Ping; Norris, Derek; Haslow, Kristin D.; Murali Dhar, T. G.; Pitts, William J.; Watterson, Scott H.; Cheney, Daniel L.; Bassolino, Donna A.; Fleener, Catherine A.; Rouleau, Katherine A.; Hollenbaugh, Diane L.; Townsend, Robert M.; Barrish, Joel C.; Iwanowicz, Edwin J.. Computed Properties of C9H7BrN2 And the article was included in Bioorganic & Medicinal Chemistry Letters on April 7 ,2003. The article conveys some information:

Screening of our inhouse compound collection led to the discovery of 5-bromo-6-aminoisoquinoline (I) as a weak inhibitor of IMPDH. Subsequent optimization of I afforded a series of novel 2-isoquinolinoaminooxazole-based inhibitors, e.g., II, with single-digit nanomolar potency against the enzyme. In the experiment, the researchers used many compounds, for example, 5-Bromoisoquinolin-6-amine(cas: 566943-98-4Computed Properties of C9H7BrN2)

5-Bromoisoquinolin-6-amine(cas: 566943-98-4) belongs to isoquinoline.Computed Properties of C9H7BrN2 Isoquinoline is a structural isomer of quinoline, and quinoline derivatives are fused ring compounds of pyridine and benzene rings, which have antiseptic, antipyretic and anti-cyclic properties, and can be used as antimalarial drugs and for the preparation of other antimalarial medicine.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

New explortion of 5-Bromoisoquinolin-6-amine

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 566943-98-4, and how the biochemistry of the body works.Electric Literature of 566943-98-4

Electric Literature of 566943-98-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.566943-98-4, Name is 5-Bromoisoquinolin-6-amine, molecular formula is C9H7BrN2. In a Article£¬once mentioned of 566943-98-4

Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors

Screening of our in-house compound collection led to the discovery of 5-bromo-6-amino-2-isoquinoline 1 as a weak inhibitor of IMPDH. Subsequent optimization of 1 afforded a series of novel 2-isoquinolinoaminooxazole-based inhibitors, represented by 17, with single-digit nanomolar potency against the enzyme.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 566943-98-4, and how the biochemistry of the body works.Electric Literature of 566943-98-4

Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem