23707-37-1, Isoquinolin-7-amine is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 117 [N-(4-TERT-BUTYL-PHENYL)-2-(ISOQUINOLIN-7-YLAMINO)-BENZAMIDE] Step A: Preparation of [2- (ISOQUINOLIN-7-YLAMINO)-BENZOIC] acid ethyl ester A mixture of 2-bromo-benzoic acid ethyl ester [(458] mg, 2.0 mmol), 7-aminoisoquinoline (144 mg, 1.0 mmol), Pd (OAc) [2] (11 mg), BINAP [(30] mg) and [K2CO3] (414 mg) in 1 mL of toluene was stirred in a sealed tube for 16 h at [105 C.] The reaction was cooled to RT, diluted with 20 mL of [CH2C12,] filtered through [CELITE] concentrated, and purified by flash column chromatography to obtain the titled compound as an oil. MS [(ES+)] : 293.3 (M+H) [+.] [CALC’D] for [C18HL6N202-292.]
The synthetic route of 23707-37-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; AMGEN INC.; WO2004/5279; (2004); A2;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem