Catalysis by palladium salts. XIII. The reductive carbonylation of nitroaromatic compounds to isocyanates with PdII and Pd0 complexes as homogeneous catalysts was written by Ugo, R.;Psaro, R.;Pizzotti, M.;Nardi, P.;Dossi, C.;Andreetta, A.;Capparella, G.. And the article was included in Journal of Organometallic Chemistry in 1991.Computed Properties of C18H14Cl2N2Pd This article mentions the following:
A study was made of the reductive carbonylation of 2,4-dinitrotoluene (2,4-DNT) to 2,4-diisocyanatotoluene (2,4-TDI) with catalysis either by [Pd(isoquinoline)2Cl2], in the presence of Fe2O3 and MoO3 or of Fe2(MoO4)3 as cocatalysts, or by Pd0 complexes without cocatalysts. In the case of catalytic systems based upon [Pd(isoquinoline)2Cl2] the reaction was carried out at about 200 °C and under 200 atm of CO to produce 2,4-TDI with high conversions and acceptable selectivities. With Pd0 complexes as catalysts good conversions were achieved at much lower temperatures (100-120 °C) but with a low selectivity when a higher pressure of CO was used (300 atm or more). An investigation of the reductive carbonylation of PhNO2 to PhNCO as a model system, together with a study of the thermal stability of [Pd(isoquinoline)2Cl2] in the presence of CO, provided evidence that the actual active catalyst was a reduced (probably zerovalent) form of palladium stabilized by the nitroarom. substrate or by some of the products from it as ligands. In the experiment, the researchers used many compounds, for example, Dichlorobis(isoquinoline)-Palladium (cas: 23807-51-4Computed Properties of C18H14Cl2N2Pd).
Dichlorobis(isoquinoline)-Palladium (cas: 23807-51-4) belongs to isoquinoline derivatives. Being an analog of pyridine, isoquinoline is a weak base, with a pKa of 5.14. Most traditional methods of generating isoquinoline do so via oxidative aromatization of dihydro- or tetrahydro-isoquinolines, usually offering some environmental or economic advantage.Computed Properties of C18H14Cl2N2Pd
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem