7742-73-6, 1,3-Dichloroisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of 1,3-dichloroisoquinoline (5.00 g, 25.2 mmol), red phosphorus, (1.72 g, 55.5 mmol), and hydriodic acid (10.5 mL, 58.1 mmol) in acetic acid (25 mL) was heated to reflux for 24 hours. The reaction mixture was cooled and poured onto ice, and the resulting solution brought to pEta 7 by the addition of ION aqueous sodium hydroxide. The solution was extracted with dichloromethane (2 x 50 mL), and the organic layers concentrated. The residue was purified by silica gel chromatography (elution with 10%EtOAc/hexanes) to provide 1.01 g (24%) of the title compound. MS (DCIZNH3) mZz 164 (M+H)+.
As the paragraph descriping shows that 7742-73-6 is playing an increasingly important role.
Reference£º
Patent; ABBOTT LABORATORIES; GOMTSYAN, Arthur R.; VOIGHT, Eric A.; BAYBURT, Erol K.; CHEN, Jun; DAANEN, Jerome F.; DIDOMENICO, JR., Stanley; KORT, Michael E.; KYM, Philip R.; MCDONALD, Heath A.; PERNER, Richard J.; SCHMIDT, Robert G.; WO2010/45401; (2010); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem