Tag: M.W=50-100

Motloch, Petr published the artcileQuantification of cooperativity in the self-assembly of H-bonded rosettes, Name: 1-Methylurea, the main research area is triaminopyrimidine barbiturate cyanate self assembly allosteric cooperativity hydrogen bond.

The self-assembly of triaminopyrimidines with barbiturates and with cyanates was investigated in chloroform solution Equimolar mixtures of two complementary components form stable macrocyclic 3 : 3 complexes (rosettes). The thermodn. of self-assembly were quantified by using 1H NMR titrations to measure the strength of pairwise H-bonding interactions between two rosette components (K), allosteric cooperativity associated with formation of a second H-bonding interaction with each component, and the effective molarity for cyclisation of the rosette motif (EM). Pyrimidine-cyanurate interactions are an order of magnitude more favorable than pyrimidine-barbiturate interactions, so the cyanurate rosettes are significantly more stable than barbiturate rosettes. There is no allosteric cooperativity associated with rosette formation, but the chelate cooperativity quantified by the product K EM is exceptionally high (102-104), indicating that there are no other species present that compete with rosette assembly. The values of EM for rosette formation are approx. 2 M for all four rosettes studied and are not affected by differences in peripheral substituents or intrinsic H-bond strength.

Organic & Biomolecular Chemistry published new progress about Allosterism. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Name: 1-Methylurea.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Li, Jie published the artcileStabilization of an intramolecular hydrogen-bond block in an s-triazine insensitive high-energy material, Synthetic Route of 1455-77-2, the main research area is stabilization intramol hydrogen bond block triazine insensitive high energy.

The simultaneous incorporation of N-oxide and nitramine is a significant approach for improving the oxygen balance, d. and detonation performance of energetic materials. Herein, an intramol. hydrogen-bond block was stabilized in novel s-triazine energetic materials. Meanwhile, as the first instance of successful N-oxidation in the s-triazine backbone, the as-synthesized energetic compounds exhibited multipurpose applications. Compound 4 showed detonation performance comparable to that of FOX-12 but more insensitive and thermally stable (IS > 80 J, Td: 275°C). Compound 5 presented excellent phys. and detonation properties similar to RDX, including high densities (up to 1.86 g cm-3), high energetic performances (calculated detonation velocity: 8762 m s-1) and low mech. sensitivities (IS = 40 J) superior to those of RDX, demonstrating promise as a novel insensitive highly energetic material.

New Journal of Chemistry published new progress about Amino group. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Li, Jie published the artcileStabilization of an intramolecular hydrogen-bond block in an s-triazine insensitive high-energy material, Recommanded Product: 3,5-Diamino-1,2,4-triazole, the main research area is stabilization intramol hydrogen bond block triazine insensitive high energy.

The simultaneous incorporation of N-oxide and nitramine is a significant approach for improving the oxygen balance, d. and detonation performance of energetic materials. Herein, an intramol. hydrogen-bond block was stabilized in novel s-triazine energetic materials. Meanwhile, as the first instance of successful N-oxidation in the s-triazine backbone, the as-synthesized energetic compounds exhibited multipurpose applications. Compound 4 showed detonation performance comparable to that of FOX-12 but more insensitive and thermally stable (IS > 80 J, Td: 275°C). Compound 5 presented excellent phys. and detonation properties similar to RDX, including high densities (up to 1.86 g cm-3), high energetic performances (calculated detonation velocity: 8762 m s-1) and low mech. sensitivities (IS = 40 J) superior to those of RDX, demonstrating promise as a novel insensitive highly energetic material.

New Journal of Chemistry published new progress about Amino group. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Recommanded Product: 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xiong, Jie published the artcileA highly fluorescent lanthanide metal-organic framework as dual-mode visual sensor for berberine hydrochloride and tetracycline, Product Details of C2H5N5, the main research area is fluorescent lanthanide metal organic framework sensor berberine hydrochloride tetracycline; Berberine hydrochloride; Dual-mode sensor; Metal-organic framework; Tetracycline; Visual detection.

A microscale highly fluorescent Eu metal-organic framework (Eu-MOF) was synthesized with terephthalic acid and 1H-1,2,4-triazole-3,5-diamine by one-pot hydrothermal method. And it was characterized by scanning electron microscope, FTIR spectroscopy, powder x-ray diffraction, fluorescence spectroscopy, TGA, and energy dispersive x-ray mapping. The prepared Eu-MOF has high quantum yield of 30.99%, excellent water dispersibility, good fluorescence stability, and favorable thermal stability. Based on the distinctly different fluorescence responses of different emission, the prepared Eu-MOF was used as dual-mode visual sensor for the sensitive detection of berberine hydrochloride and tetracycline. The limits of detection are 78 nM and 17 nM, resp. The sensing mechanism is also discussed. Moreover, a filter paper sensor has been designed for sensing tetracycline with a notable fluorescence color change from blue to red. The prepared Eu-MOF is promising to be developed as a multi-mode luminescent sensor for visual detection in biochem. anal.

Analytical and Bioanalytical Chemistry published new progress about Filter paper. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Product Details of C2H5N5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xiong, Jie published the artcileA highly fluorescent lanthanide metal-organic framework as dual-mode visual sensor for berberine hydrochloride and tetracycline, Synthetic Route of 1455-77-2, the main research area is fluorescent lanthanide metal organic framework sensor berberine hydrochloride tetracycline; Berberine hydrochloride; Dual-mode sensor; Metal-organic framework; Tetracycline; Visual detection.

A microscale highly fluorescent Eu metal-organic framework (Eu-MOF) was synthesized with terephthalic acid and 1H-1,2,4-triazole-3,5-diamine by one-pot hydrothermal method. And it was characterized by scanning electron microscope, FTIR spectroscopy, powder x-ray diffraction, fluorescence spectroscopy, TGA, and energy dispersive x-ray mapping. The prepared Eu-MOF has high quantum yield of 30.99%, excellent water dispersibility, good fluorescence stability, and favorable thermal stability. Based on the distinctly different fluorescence responses of different emission, the prepared Eu-MOF was used as dual-mode visual sensor for the sensitive detection of berberine hydrochloride and tetracycline. The limits of detection are 78 nM and 17 nM, resp. The sensing mechanism is also discussed. Moreover, a filter paper sensor has been designed for sensing tetracycline with a notable fluorescence color change from blue to red. The prepared Eu-MOF is promising to be developed as a multi-mode luminescent sensor for visual detection in biochem. anal.

Analytical and Bioanalytical Chemistry published new progress about Filter paper. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

da Costa Filho, Paulo Augusto published the artcileRapid analysis of food raw materials adulteration using laser direct infrared spectroscopy and imaging, HPLC of Formula: 598-50-5, the main research area is food raw material adulteration laser direct IR spectroscopy imaging.

The objective of this study was to assess the application of the Laser Direct IR (LDIR) imaging system as a rapid screening technol. for detection, identification, and semi-quantitation of adulterants in food ingredients. Forty-five samples of skimmed milk powder, thirty-one samples of soy protein isolate, thirty-five samples of chicken meat powder, thirty-two samples of pea protein isolate and six samples of wheat flour were dry blended adulterated with nitrogen-rich compounds and bulking agents at concentrations of 1.0-15.0% (weight/weight). In addition, ten samples of skimmed milk powder were wet blended with food adulterants at 5.0% and 10.0% (weight/weight) to check the LDIR performance when different fraudulent processes are applied. The results from this study shows that LDIR can be used as a rapid untargeted screening method that are independent of adulterants to detect, identify and semi-quantify food adulterants in dry blended samples. In most samples, the technol. accurately identified all nitrogen-rich compounds and bulking agents present in the dry blended samples. In addition, the technol. shows sensitivity of 82% for samples adulterated at 1% and sensitivity from 92% to 100% for samples adulterated at �5% economic adulteration. On the other hand, the detection and identification of food adulterants in samples prepared by wet blending process was more challenging than dry blended samples because mid-IR technol. may not be sensitive enough to detect adulterants if they are dissolved or if hidden within the particles.

Food Control published new progress about Chicken meat. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, HPLC of Formula: 598-50-5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Jin, Lei published the artcileSimultaneous optimization of the extraction process of Yangyin Yiqi Huoxue prescription with natural deep eutectic solvents for optimal extraction yield and antioxidant activity: A comparative study of two models, Computed Properties of 598-50-5, the main research area is Yangyin Yiqi Huoxue prescription extraction optimization deep eutectic solvent; Genetic neural network; Natural deep eutectic solvents; Response surface methodology; Yangyin Yiqi Huoxue prescription; bi-objective optimization.

Natural deep eutectic solvents (NaDESs) are green and effective solvents that are used to extract 3 flavonoids from Yangyin Yiqi Huoxue prescription, a traditional Chinese prescription. A total of 6 types of NaDESs were systematically screened and evaluated for the total extraction yield of puerarin, calycosin, and formononetin by high-performance liquid chromatog. Then, a 4-factor-three-level exptl. scheme designed by the Box-Benhnken Design was applied on the basis of a single experiment to determine the extraction yield and the antioxidant property. Finally, the extraction process was optimized through response surface methodol. (RSM) and the genetic neural network (GNN), resp. The use of betaine-lactic acid as an extractant displayed significant advantages in the screening process. The optimum extraction parameters provided by GNN were as follows: water content 25% (volume/volume), liquid to material ratio 190 mg/mL, extraction time 37 min, and extraction temperature 63°C. Under this condition, the average exptl. comprehensive evaluation values of the extraction yield and antioxidant properties were 3.12 mg/g and 86.27%, and the relative deviations to the predicted values were 0.30% and 1.44%, resp. In addition, the exptl. results of GNN were better than those of RSM (p < 0.01). We found the application of GNN to be effective and credible for bi-objective optimization of extraction yields and antioxidant activity in this study. Moreover, our results provide a reference and a theor. basis for exptl. and future industrial extraction for multi-objective situations. Phytomedicine published new progress about Antioxidants. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Computed Properties of 598-50-5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Feng, Xiaoquan published the artcileHigh-flux polyamide membrane with improved chlorine resistance for efficient dye/salt separation based on a new N-rich amine monomer, Safety of 3,5-Diamino-1,2,4-triazole, the main research area is amine monomer polyamide membrane chlorine resistance.

Interfacial polymerization is the gold standard for manufacturing thin film composite (TFC) membranes for nanofiltration (NF) and reverse osmosis (RO). However, typical polyamide (PA) thin film composite (TFC) membranes fabricated by interfacial polymerization are inappropriate for dye wastewater zero discharge and are susceptible to oxidizing agents. In this study, by using a new N-rich amine monomer 3,5-diamino-1,2,4-triazole (DAT), a novel PA TFC membrane was fabricated for the separation of dyes and salts. It is speculated that the unique mol. structure of DAT can conducive to the formation of a less compact polyamide layer with improved chlorine resistance. The optimum membrane shows an ultrahigh pure water permeability (95.1 L/m2·h·bar) and an excellent dye/salt separation selectivity for Congo red and NaCl (rejection, 99.1% and 5.8%, resp.). This is superior to that of the two commonly used dye/salt separation com. membranes (Sepro NF 6 and NF 2A, Ultura). Furthermore, the resultant DAT/TMC TFC membranes maintained their original separation efficacy after 120 h of immersion in NaClO solution, demonstrating their good chlorine resistance. In summary, this study not only expands the application of interfacial polymerization, but also provides a new inspiration for the preparation of advanced membranes for efficient dye/salt separation

Separation and Purification Technology published new progress about Contact angle. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Safety of 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Feng, Xiaoquan published the artcileHigh-flux polyamide membrane with improved chlorine resistance for efficient dye/salt separation based on a new N-rich amine monomer, HPLC of Formula: 1455-77-2, the main research area is amine monomer polyamide membrane chlorine resistance.

Interfacial polymerization is the gold standard for manufacturing thin film composite (TFC) membranes for nanofiltration (NF) and reverse osmosis (RO). However, typical polyamide (PA) thin film composite (TFC) membranes fabricated by interfacial polymerization are inappropriate for dye wastewater zero discharge and are susceptible to oxidizing agents. In this study, by using a new N-rich amine monomer 3,5-diamino-1,2,4-triazole (DAT), a novel PA TFC membrane was fabricated for the separation of dyes and salts. It is speculated that the unique mol. structure of DAT can conducive to the formation of a less compact polyamide layer with improved chlorine resistance. The optimum membrane shows an ultrahigh pure water permeability (95.1 L/m2·h·bar) and an excellent dye/salt separation selectivity for Congo red and NaCl (rejection, 99.1% and 5.8%, resp.). This is superior to that of the two commonly used dye/salt separation com. membranes (Sepro NF 6 and NF 2A, Ultura). Furthermore, the resultant DAT/TMC TFC membranes maintained their original separation efficacy after 120 h of immersion in NaClO solution, demonstrating their good chlorine resistance. In summary, this study not only expands the application of interfacial polymerization, but also provides a new inspiration for the preparation of advanced membranes for efficient dye/salt separation

Separation and Purification Technology published new progress about Contact angle. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, HPLC of Formula: 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Oprea, Stefan published the artcileThe effects of the inclusion of 1,2,4-triazole derivatives into the main chains of the polyurethane urea exposed to UV radiation, HPLC of Formula: 1455-77-2, the main research area is polyurethane urea triazole UV irradiation mech property surface morphol.

Linear polyurethane urea containing 1,2,4-triazole segments was obtained by polyaddition of the 3,5-diamino-1,2,4-triazole (DATA) to urethane prepolymer. Also, three crosslinked polymers with different crosslinkers (2,4,6-triaminopyrimidine (TAP), glycerin (Gly), castor oil (CO)) were synthesized. Thermogravimetric anal., of the obtained polymers, indicated good thermal stability up to 310°C. The polyurethane urea chem. structure was confirmed by FTIR anal. The glass transition temperatures (Tg) of these polymers, measured by differential scanning calorimetry (DSC), were found in the range of -52°C to -56°C. These values were not significantly influenced by the structure of the hard domain and the intermol. interactions. The tensile testing showed that the inclusion of 1,2,4-triazole in polyurethane structure substantially improves the tensile strength up to 58 MPa. The obtained polyurethane urea presents surface slight hydrophobic and low interfacial tension. The pos. effect of the 1,2,4-triazole segment from the polymer main chain in the UV aging process of these polymer materials has been studied. After exposure to UV radiation, few changes were observed in the mol. structure, in the surface morphol. and the mech. properties.

High Performance Polymers published new progress about Contact angle. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, HPLC of Formula: 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem