Tag: M.W=600-700

Velo-Gala, Inmaculada published the artcileIonic X-ray contrast media degradation in aqueous solution induced by gamma radiation, Application of Diatrizoic Acid, the main research area is ionic x ray contrast media degradation gamma radiation.

The objective of this study was to analyze the effectiveness of gamma irradiation to transform diatrizoate, DTZ, (contrast medium) in aqueous solution determining the role of oxidizing and reducting species on DTZ degradation The mechanisms involved in DTZ degradation have also been studied. Removal of 91.9% of the diatrizoate was achieved at a dose of 1000 Gy at initial concentration of 25 mg/L. The degradation rate depends on the initial concentration The dose constant is independent of the dose rate in the studied range of 3.83-1.06 Gy/min and slightly depends on solution pH in the interval pH 2.0-10.0. Results obtained show that low H2O2 concentrations increase the efficacy of the process, and high concentrations markedly decrease the dose constant The reaction constant of diatrizoate with the hydrogen radical was determined, obtaining a kH[rad] (DTZ) value of (2.2 ± 0.5) × 109 M-1 s-1. DTZ irradiation byproducts have been determined by HPLC-MS and an oxidation/reduction mechanism has been proposed. Three possible degradation pathways based on the major byproducts found at different doses have been proposed. Moreover, the results obtained indicated a further possible compound degradation pathway, which is based on decarboxylation by hydrogen radical or HO· radical with a subsequent attack by hydroxyl radicals against the ketone group.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Gamma ray. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application of Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Forrez, Ilse published the artcileBiogenic metals for the oxidative and reductive removal of pharmaceuticals, biocides and iodinated contrast media in a polishing membrane bioreactor, Name: Diatrizoic Acid, the main research area is biogenic metal oxidation reduction pharmaceutical biocide polishing membrane bioreactor; biocide iodinated contrast media.

Pharmaceutical and personal care products, biocides and iodinated contrast media (ICM) are persistent compounds, which appear in ng to μg L-1 in secondary effluents of sewage treatment plants (STPs). In this work, biogenic metals manganese oxides (BioMnOx) and bio-palladium (Bio-Pd) were applied in lab-scale membrane bioreactors (MBR) as oxidative and reductive technologies, resp., to remove micropollutants from STP-effluent. From the 29 substances detected in the STP-effluent, 14 were eliminated in the BioMnOx-MBR: ibuprofen (>95%), naproxen (>95%), diuron (>94%), codeine (>93%), N-acetyl-sulfamethoxazole (92%), chlorophene (>89%), diclofenac (86%), mecoprop (81%), triclosan (>78%), clarithromycin, (75%), iohexol (72%), iopromide (68%), iomeprol (63%) and sulfamethoxazole (52%). The putative removal mechanisms were the chem. oxidation by BioMnOx and/or the biol. removal by Pseudomonas putida and associated bacteria in the enriched biofilm. Yet, the removal rates (highest value: 2.6 μg diclofenac L-1 d-1) need to improve by a factor 10 in order to be competitive with ozonation. ICM, persistent towards oxidative techniques, were successfully dehalogenated with a novel reductive technique using Bio-Pd as a nanosized catalyst in an MBR. Iomeprol, iopromide and iohexol were removed for >97% and the more recalcitrant diatrizoate for 90%. The conditions favorable for microbial H2-production enabling the charging of the Pd catalyst, were shown to be important for the removal of ICM. Overall, the results indicate that Mn oxide and Pd coupled to microbial catalysis offer novel potential for advanced water treatment.

Water Research published new progress about Oxidation. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Name: Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Howard, Philip H. published the artcileIdentifying New Persistent and Bioaccumulative Organics Among Chemicals in Commerce II: Pharmaceuticals, Formula: C11H9I3N2O4, the main research area is identifying persistent bioaccumulative organic chem commerce pharmaceutical.

The goal was to identify com. pharmaceuticals that might be persistent and bioaccumulative (P&B) and that were not being considered in current wastewater and aquatic environmental measurement programs. We developed a database of 3193 pharmaceuticals from 2 US Food and Drug Administration (FDA) databases and some lists of top ranked or selling drugs. Of the 3193 pharmaceuticals, 275 pharmaceuticals have been found in the environment and 399 pharmaceuticals were, based on production volumes, designated as high production volume (HPV) pharmaceuticals. All pharmaceuticals that had reported chem. structures were evaluated for potential bioaccumulation (B) or persistence (P) using quant. structure property relationships (QSPR) or scientific judgment. Of the 275 drugs detected in the environment, 92 were rated as potentially bioaccumulative, 121 were rated as potentially persistent, and 99 were HPV pharmaceuticals. After removing the 275 pharmaceuticals previously detected in the environment, 58 HPV compounds were identified that were both P&B and 48 were identified as P only. Of the non-HPV compounds, 364 pharmaceuticals were identified that were P&B. This study has yielded some interesting and probable P&B pharmaceuticals that should be considered for further study.

Environmental Science & Technology published new progress about Antacids. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Formula: C11H9I3N2O4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Li, Cheng-Hung published the artcileFluorescence-Guided Probes of Aptamer-Targeted Gold Nanoparticles with Computed Tomography Imaging Accesses for in Vivo Tumor Resection, Recommanded Product: Diatrizoic Acid, the main research area is tumor resection aptamer gold nanoparticles computed tomog imaging.

Recent development of mol. imaging probes for fluorescence-guided surgery has shown great progresses for determining tumor margin to execute the tissue resection. Here we synthesize the fluorescent gold nanoparticles conjugated with diatrizoic acid and nucleolin-targeted AS1411 aptamer. The nanoparticle conjugates exhibit high water-solubility, good biocompatibility, visible fluorescence and strong X-ray attenuation for computed tomog. (CT) contrast enhancement. The fluorescent nanoparticle conjugates are applied as a mol. contrast agent to reveal the tumor location in CL1-5 tumor-bearing mice by CT imaging. Furthermore, the orange-red fluorescence emitting from the conjugates in the CL1-5 tumor can be easily visualized by the naked eyes. After the resection, the IVIS measurements show that the fluorescence signal of the nanoparticle conjugates in the tumor is greatly enhanced in comparison to that in the controlled experiment Our work has shown potential application of functionalized nanoparticles as a dual-function imaging agent in clin. fluorescence-guided surgery.

Scientific Reports published new progress about Aptamers. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Recommanded Product: Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Shuai, Danmeng published the artcileEnhancement of Oxyanion and Diatrizoate Reduction Kinetics Using Selected Azo Dyes on Pd-Based Catalysts, Recommanded Product: Diatrizoic Acid, the main research area is oxyanion diatrizoate reduction kinetic azo dye palladium catalyst wastewater.

Azo dyes are widespread pollutants and potential cocontaminants for nitrate; we evaluated their effect on catalytic reduction of a suite of oxyanions, diatrizoate, and N-nitrosodimethylamine (NDMA). The azo dye Methyl orange significantly enhanced (a factor of �.24) the catalytic reduction kinetics of nitrate, nitrite, bromate, perchlorate, chlorate, and diatrizoate with several different Pd-based catalysts; NDMA reduction was not enhanced. Nitrate was selected as a probe contaminant, and a variety of azo dyes (Methyl orange, Methyl red, Fast Yellow Ab, Metanil Yellow, Acid Orange 7, Congo Red, Eriochrome Black T, Acid Red 27, Acid Yellow 11, and Acid Yellow 17) were evaluated for their ability to enhance reduction Hydrogenation energies of azo dyes were calculated using d. functional theory and a volcano relation between hydrogenation energies and reduction rate enhancement was observed A kinetic model based on Bronsted-Evans-Polanyi (BEP) theory matched the volcano relation and suggests sorbed azo dyes enhance reduction kinetics through H atom shuttling between reduced azo dyes (i.e., hydrazo dyes) and oxyanions or diatrizoate. This is the 1st research that has identified this synergetic effect, and it has implications for designing more efficient catalysts and reducing Pd costs in water treatment systems.

Environmental Science & Technology published new progress about Azo dyes. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Recommanded Product: Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Yang, Dingwei published the artcileNa+/Ca2+ exchange inhibitor, KB-R7943, attenuates contrast-induced acute kidney injury, Application In Synthesis of 117-96-4, the main research area is KBR7943 renoprotectant sodium calcium exchanger inhibitor acute kidney injury.

Background: Intracellular Ca2+ overload is considered to be a key factor in contrast-induced acute kidney injury (CI-AKI). The Na+/Ca2+ exchanger (NCX) system is one of the main pathways of intracellular Ca2+ overload. We investigated the effects of KB-R7943, an inhibitor of the reverse mode of NCX, on CI-AKI in a rat model. Method: Rats were divided into control group, CI-AKI group and pretreatment groups (with KB-R7943 dose of 5 or 10 mg/kg). CI-AKI was induced by diatrizoate administration in rats with cholesterol-supplemented diet for 8 wk. Renal function and renal hemodynamics were determined 1 day following contrast medium administration. Renal histopathol. was observed by light microscope. Renal tubular apoptosis was examined by TUNEL. Renal endothelin-1 (ET-1) was measured by RIA. Renal malondialdehyde (MDA) and catalase (CAT) were measured as oxidative markers. Results: Levels of serum creatinine (Scr), renal ET-1, MDA and CAT, and resistance index (RI) of renal blood vessels increased significantly in CI-AKI rats. The increases in Scr and RI of renal blood vessels induced by diatrizoate were suppressed significantly and dose-dependently by pretreatment with KB-R7943. Histopathol. and TUNEL results showed that the contrast medium-induced severe renal tubular necrosis and apoptosis were significantly and dose-dependently attenuated by KB-R7943. KB-R7943 significantly suppressed the increment of renal ET-1 content and MDA and CAT level induced by contrast medium administration. Conclusion: Activation of the reverse mode of NCX, followed by ET-1 overproduction and increased oxidative stress, seems to play an important role in the pathogenesis of CI-AKI. The inhibitor of the reverse mode of NCX, KB-R7943, has renoprotective effects on CI-AKI.

Journal of Nephrology published new progress about Apoptosis. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application In Synthesis of 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Hennebel, Tom published the artcileDehalogenation of environmental pollutants in microbial electrolysis cells with biogenic palladium nanoparticles, Application In Synthesis of 117-96-4, the main research area is microbial electrolysis cell palladium trichloroethylene dechlorination catalytic groundwater remediation.

Purpose of work Hydrodehalogenation of persistent pollutants, such as the groundwater contaminants trichloroethylene and diatrizoate, are catalyzed by biogenic Pd nanoparticles. As H2 gas supply for the dehalogenation reactions is still the limiting factor, this study examines in situ H2 production in the cathode of a microbial electrolysis cell. In a biogenic Pd nanoparticle (bio-Pd) free microbial electrolysis cell (MEC), dechlorination of trichloroethylene (TCE) with concomitant chloride and ethane formation was achieved in the cathode compartment at a removal rate of 120 g TCE m-3 total cathode compartment (TCC) day-1, applying -0.8 V with a power source. When the cathode granules were coated with 5 mg bio-Pd g-1 graphite, chloride and ethane formation increased to 151 g TCE m-3 TCC day-1 corresponding with a specific removal rate of 48 mg TCE g-1 Pd day-1. In both cases, formation of unwanted byproducts, such as vinyl chloride, was not significant. When the same setup was applied for transformation of the iodinated contrast medium diatrizoate (diaI3), reduction in a catalyst-free cathode of a MEC resulted in a removal of 48 ± 9% during the first h corresponding to 3 g diaI3 m-3 TCC day-1. Coating the cathodic graphite granules with bio-Pd enhanced the transformation resulting in a 93 ± 4% removal during the first h corresponding to 6 g diaI3 m-3 TCC day-1. These results suggest that MECs can produce H2 in a sustainable way to provide an economical interesting reactant for bio-Pd catalyzed dehalogenation reactions.

Biotechnology Letters published new progress about Catalysis. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application In Synthesis of 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Van Nevel, S. published the artcilePalladium nanoparticles produced by fermentatively grown bacteria as catalyst for diatrizoate removal with biogenic hydrogen, Formula: C11H9I3N2O4, the main research area is Citrobacter Clostridium biogenic palladium nanoparticle formation.

This study demonstrated the general applicability of fermentatively grown bacteria (Clostridium butyricum and Citrobacter braakii) to generate catalytic Pd(0) nanoparticles and biol. produced hydrogen as electron donor. A process consisting of microbial hydrogen formation and Pd nanoparticle catalysis without the need for an external electron donor was studied in dehalogenation reactions in batch tests as well as in a membrane bioreactor (MBR) using diatrizoate as model compound The results of using biogenic Pd(0) for diatrizoate dehalogenation in batch experiments and for removal of diatrizoate in an MBR are presented.

Communications in Agricultural and Applied Biological Sciences published new progress about Catalysis. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Formula: C11H9I3N2O4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Loos, Robert published the artcileEU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents, Safety of Diatrizoic Acid, the main research area is polar organic chem effluent marine water pollution Europe; Effluent water; European wide monitoring; Pharmaceuticals and personal care products (PPCPs); Polar organic contaminants; Wastewater treatment plants (WWTPs).

In the year 2010, effluents from 90 European wastewater treatment plants (WWTPs) were analyzed for 156 polar organic chem. contaminants. The analyses were complemented by effect-based monitoring approaches aiming at estrogenicity and dioxin-like toxicity analyzed by in vitro reporter gene bioassays, and yeast and diatom culture acute toxicity optical bioassays. Analyses of organic substances were performed by solid-phase extraction (SPE) or liquid-liquid extraction (LLE) followed by liquid chromatog. tandem mass spectrometry (LC-MS-MS) or gas chromatog. high-resolution mass spectrometry (GC-HRMS). Target microcontaminants were pharmaceuticals and personal care products (PPCPs), veterinary (antibiotic) drugs, perfluoroalkyl substances (PFASs), organophosphate ester flame retardants, pesticides (and some metabolites), industrial chems. such as benzotriazoles (corrosion inhibitors), iodinated x-ray contrast agents, and gadolinium magnetic resonance imaging agents; in addition biol. endpoints were measured. The obtained results show the presence of 125 substances (80% of the target compounds) in European wastewater effluents, in concentrations ranging from low nanograms to milligrams per L. These results allow for an estimation to be made of a European median level for the chems. investigated in WWTP effluents. The most relevant compounds in the effluent waters with the highest median concentration levels were the artificial sweeteners acesulfame and sucralose, benzotriazoles (corrosion inhibitors), several organophosphate ester flame retardants and plasticizers (e.g. tris(2-chloroisopropyl)phosphate; TCPP), pharmaceutical compounds such as carbamazepine, tramadol, telmisartan, venlafaxine, irbesartan, fluconazole, oxazepam, fexofenadine, diclofenac, citalopram, codeine, bisoprolol, eprosartan, the antibiotics trimethoprim, ciprofloxacine, sulfamethoxazole, and clindamycine, the insect repellent N,N’-diethyltoluamide (DEET), the pesticides MCPA and mecoprop, perfluoroalkyl substances (such as PFOS and PFOA), caffeine, and gadolinium.

Water Research published new progress about Pesticides. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Safety of Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Thamaraiselvan, Chidambaram published the artcileCoupled electrochemical transformation and filtration of water pollutants by cathodic-carbon nanotube membranes, Computed Properties of 117-96-4, the main research area is electrochem transformation filtration water pollution cathodic carbon nanotube membrane.

This study aimed at evaluating the concomitant electrochem. reduction and separation of organic and inorganic model contaminants from water. A highly conductive (40,000 S/m) support free carbon nanotube (CNT) membrane was used as a cathode in a three-electrode electrochem. crossflow membrane filtration system. Diatrizoate (DTZ), a recalcitrant iodinated contrast media; resazurin (RZ), a redox indicator; and hexavalent chromium ion (Cr(VI)), a ‘gold’ standard for characterization of reducing systems, were tested as model contaminants. Voltages of -0.6 to -1.0 V were enough to remove between 90% and 95% of the three model contaminants tested. Removal of Cr(VI) proceeded by reduction to Cr(III) followed by adsorption onto the cathode, which could be efficiently regenerated (up to 95%) applying reversal (anodic) potential. Preliminary findings applying AC current (0.6-1.5 V, 10 Hz-1 kHz) suggest that it could be a feasible approach for detoxification with minimization of membrane clogging. Resazurin was immediately transformed into resorufin to near completion which was in turn further reduced to dihydroresorufin. The reductive transformation of DTZ resulted in almost complete deiodination, leading to the accumulation of 3,5-diacetamidobenzoic acid as the main end-product. Although other five secondary transformation products were detected, four of them were fully deiodinated. Concluding, the proposed electrochem. filtration cell equipped with a highly conductive CNT-cathodic membrane can be regarded as a potential technique for water decontamination and effective dehalogenation of organic compounds

Journal of Environmental Chemical Engineering published new progress about Acylation. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Computed Properties of 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem