Category: 151-10-0

Omrani, Assia published the artcileBi(OTf)3-catalyzed regioselective arylation of Morita-Baylis-Hillman type allylic electrophiles, COA of Formula: C8H10O2, the main research area is allylic electrophile arene bismuth triflate regioselective Friedel Crafts arylation; aryl alkenone preparation.

The Friedel-Crafts reaction of a wide variety of arenes and heteroarenes was accomplished, in good to excellent yields (50-98%) and with high α-regioselectivity, using Morita-Baylis-Hillman acetates. Functionalized conjugated enones were obtained under Bi(OTf)3 catalysis (10 mol%) in dichloroethane (DCE) at 50°.

Tetrahedron Letters published new progress about Aryl ketones Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, COA of Formula: C8H10O2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Ruiz-Moyano, Santiago published the artcileSelection and application of antifungal VOCs-producing yeasts as biocontrol agents of grey mould in fruits, Related Products of isoquinoline, the main research area is antifungal volatile compound yeast gray mold fruit; Antifungal volatile compounds; Botrytis cinerea; Cherry; Postharvest; Strawberry.

Rotting caused by gray mold (Botrytis cinerea) is a concerning disease for numerous crops both pre- and postharvest stages. Application of antagonistic yeasts is a promising strategy for controlling gray mold incidence which could mitigate undesirable consequences of using synthetic fungicides. In this work, a screening for detection of yeasts isolated from figs producers of antifungal volatile organic compounds (VOCs) were performed by confrontation in double dishes systems. Eleven out of 34 yeasts confronted reduced B. cinerea growth parameter in vitro. This reduction was correlated (p ≤ 0.050) with the production of 10 volatile compounds: two acids (acetic acid and octanoic acid), 7 esters (Et propionate, n-Pr acetate, Iso-Bu acetate, 2-methylbutyl acetate, furfuryl acetate, phenylmethyl acetate, 2-phenylethyl acetate) and one ketone (Heptan-2-one). In bases on in vitro assay, Hanseniaspora uvarum 793 was applied to in vivo assays with strawberries and cherries. The reduction of incidence of B. cinerea in strawberries at 7°C and 25°C was 54.9 and 72.1% after 6 and 3 days, resp. The reduction of incidence of B. cinerea in cherries at 7°C and 25°C was 48.9 and 45.6% after 5 and 4 days, resp. These results showed that VOCs produced by Hanseniaspora uvarum 793 are effective in the control of incidence of Botrytis cinerea in fruits, being a potential alternative to chem. fungicide.

Food Microbiology published new progress about Acyclic hydrocarbons Role: ANT (Analyte), ANST (Analytical Study). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Pan, Aaron published the artcileSynergistic Bronsted/Lewis acid catalyzed aromatic alkylation with unactivated tertiary alcohols or di-tert-butylperoxide to synthesize quaternary carbon centers, Product Details of C8H10O2, the main research area is aromatic hydrocarbon ditert butylperoxide acid catalyst regioselective alkylation green; tertiary alc aromatic hydrocarbon acid catalyst regioselective alkylation green; quaternary alkylarene preparation.

Dual Bronsted/Lewis acid catalysis involving environmentally benign, readily accessible protic acid and iron promotes site-selective tert-butylation of electron-rich arenes using di-tert-butylperoxide. This transformation inspired the development of a synergistic Bronsted/Lewis acid catalyzed aromatic alkylation that fills a gap in the Friedel-Crafts reaction literature by employing unactivated tertiary alcs. as alkylating agents, leading to new quaternary carbon centers. Corroborated by DFT calculations, the Lewis acid serves a role in enhancing the acidity of the Bronsted acid. The use of non-allylic, non-benzylic, and non-propargylic tertiary alcs. represents an underexplored area in Friedel-Crafts reactivity.

Chemical Science published new progress about Alkylarenes Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Product Details of C8H10O2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Singh, Dileep Kumar published the artcileOne-pot, three-component approach to diarylacetonitriles, Formula: C8H10O2, the main research area is aromatic aldehyde heteroarene trimethylsilyl cyanide three component reaction; diarylacetonitrile preparation one pot.

A novel one-pot, three-component reaction where aldehydes, electron-rich arenes, and TMSCN in the presence of BF3-OEt2 allowed direct access to a number of diarylacetonitriles under mild reaction conditions in good to excellent yields. Implementation of this assembly protocol to a concise synthetic approach to shoreaphenol, a bioactive oligostilbenoid natural product, was also demonstrated.

Organic Chemistry Frontiers published new progress about Acetonitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Formula: C8H10O2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Vayer, Marie published the artcilePotassium Carbonate to Unlock a GaCl3-Catalyzed C-H Propargylation of Arenes, COA of Formula: C8H10O2, the main research area is electron rich arene bromoallene carbon hydrogen propargylation; gallium chloride catalyst potassium carbonate base.

A gallium-catalyzed C-H propargylation of electron-rich arenes using bromoallenes is described. The development of this reaction was first hampered by a side hydroarylation process catalyzed by adventitious protons, easily generated from the solvent (1,2-dichloroethane). This hidden Bronsted acid catalysis could be bypassed by using K2CO3 as insoluble base. The unexpected compatibility of this base with the Lewis acid catalyst GaCl3 allowed a strictly gallium-catalyzed process that was thoroughly studied by kinetics, 71Ga NMR experiments and DFT computations. The GaCl3/K2CO3 system triggers the C-H propargylation of a wide range of arenes and heteroaromatics using a variety of bromoallenes.

ACS Catalysis published new progress about Alkynes, aryl Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, COA of Formula: C8H10O2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Esteruelas, Miguel A. published the artcileDirect C-H Borylation of Arenes Catalyzed by Saturated Hydride-Boryl-Iridium-POP Complexes: Kinetic Analysis of the Elemental Steps, Safety of 1,3-Dimethoxybenzene, the main research area is carbon hydrogen bond borylation arene catalyst boryliridium hydride; isotope effect borylation arene catalyst boryliridium hydride; reductive elimination kinetics boryl iridium hydride pincer complex; B−H activation; C−H activation; arene borylation; iridium; pincer ligand.

The saturated trihydride IrH3{κ3-P,O,P-[xant(PiPr2)2]} (1; xant(PiPr2)2 = 9,9-dimethyl-4,5-bis(diisopropylphosphino)xanthene) activates the B-H bond of two mols. of pinacolborane (HBpin) to give H2, the hydride-boryl derivatives IrH2(Bpin){κ3-P,O,P-[xant(PiPr2)2]} (2) and IrH(Bpin)2{κ3-P,O,P-[xant(PiPr2)2]} (3) in a sequential manner. Complex 3 activates a C-H bond of two mols. of benzene to form PhBpin and regenerates 2 and 1, also in a sequential manner. Thus, complexes 1, 2, and 3 define two cycles for the catalytic direct C-H borylation of arenes with HBpin, which have dihydride 2 as a common intermediate. C-H bond activation of the arenes is the rate-determining step of both cycles, as the C-H oxidative addition to 3 is faster than to 2. The results from a kinetic study of the reactions of 1 and 2 with HBpin support a cooperative function of the hydride ligands in the B-H bond activation. The addition of the B atom of the borane to a hydride facilitates the coordination of the B-H bond through the formation of κ1- and κ2-dihydrideborate intermediates.

Chemistry – A European Journal published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Gairola, Deepti published the artcileMethanesulfonic Acid Catalyzed Friedel-Crafts Reaction of Electron-Rich Arenes with N-Arylmaleimides: A Highly Efficient Metal-Free Route To Access 3-Arylsuccinimides, SDS of cas: 151-10-0, the main research area is succinimide diaryl green preparation; maleimide aryl Friedel Crafts coupling arene methanesulfonic acid catalyst.

Herein, a highly efficient, metal-free and environmentally benign protocol for the synthesis of 3-arylsuccinimides I [R = Ph, 4-MeOC6H4, 3-Cl-4-MeOC6H3, etc.; Ar = 2,4-(MeO)2C6H3, 2,4-(HO)2C6H3, 2,4,6-(MeO)3C6H2, 2-hydroxy-1-naphthyl, 1-methyl-3-indolyl] in high yields via F-C coupling of electron-rich arenes with N-arylmaleimides in the presence of a green reagent methanesulfonic acid under mild reaction conditions has been developed.

Synthesis published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Lu, Shiyao published the artcileFriedel-Crafts trifluoromethylthiolation of electron-rich (hetero)arenes with trifluoromethylthio-saccharin in 2,2,2-trifluoroethanol (TFE), SDS of cas: 151-10-0, the main research area is arene trifluoromethylthio saccharin Friedel Crafts trifluoromethylthiolation; trifluoromethylthio arene preparation.

A promoter-free Friedel-Crafts trifluoromethylthiolation of electron-rich arenes and heteroarenes with N-trifluoromethylthiosaccharin using 2,2,2-trifluoroethanol (TFE) as the solvent was described. The reactions were conducted at 40° and a variety of common functional groups were compatible.

Chinese Chemical Letters published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xu, Yingzhou published the artcileRegioselective bromination of arenes mediated by triphosgene-oxidized bromide, Name: 1,3-Dimethoxybenzene, the main research area is bromoarene preparation regioselective; arene bromination triphosgene oxidized bromide mediated.

This article first time described triphosgene (BTC) as an oxidant while the non-toxic and easy-to-handle potassium bromide (KBr) as the source of bromine for the bromination reaction of aromatic substrates to afford bromoarenes. The novel brominating protocol gave excellent para-regioselectivity of the alkoxyl/hydroxyl arenes and high yield, offering good potential of com. scale applications. The mechanism of “”triphosgene oxidize bromide”” was proposed.

Tetrahedron published new progress about Aryl bromides Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Name: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Bomon, Jeroen published the artcileEfficient demethylation of aromatic methyl ethers with HCl in water, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is alc aryl preparation green chem; aryl methyl ether demethylation hydrochloric acid catalyst.

A green, efficient and cheap demethylation reaction of aromatic Me ethers, e.g., 2H-1,3-benzodioxole-5-carbaldehyde with mineral acid (HCl or H2SO4) as a catalyst in high temperature pressurized water provided the corresponding aromatic alcs.e.g., 3,4-dihydroxybenzaldehyde in high yield. 4-Propylguaiacol was chosen as a model, given the various applications of the 4-propylcatechol reaction product. This demethylation reaction could be easily scaled and biorenewable 4-propylguaiacol from wood and clove oil could also be applied as a feedstock. Greenness of the developed method vs. state-of-the-art demethylation reactions was assessed by performing a quant. and qual. Green Metrics anal. Versatility of the method was shown on a variety of aromatic Me ethers containing (biorenewable) substrates, yielding up to 99% of the corresponding aromatic alcs., in most cases just requiring simple extraction as work-up.

Green Chemistry published new progress about Alkyl aryl ethers Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem