Vayer, Marie published the artcilePotassium Carbonate to Unlock a GaCl3-Catalyzed C-H Propargylation of Arenes, COA of Formula: C8H10O2, the main research area is electron rich arene bromoallene carbon hydrogen propargylation; gallium chloride catalyst potassium carbonate base.
A gallium-catalyzed C-H propargylation of electron-rich arenes using bromoallenes is described. The development of this reaction was first hampered by a side hydroarylation process catalyzed by adventitious protons, easily generated from the solvent (1,2-dichloroethane). This hidden Bronsted acid catalysis could be bypassed by using K2CO3 as insoluble base. The unexpected compatibility of this base with the Lewis acid catalyst GaCl3 allowed a strictly gallium-catalyzed process that was thoroughly studied by kinetics, 71Ga NMR experiments and DFT computations. The GaCl3/K2CO3 system triggers the C-H propargylation of a wide range of arenes and heteroaromatics using a variety of bromoallenes.
ACS Catalysis published new progress about Alkynes, aryl Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, COA of Formula: C8H10O2.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem