Li, Xuefei team published research on Organic Letters in 2021 | 1532-97-4

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., SDS of cas: 1532-97-4

In a broader sense, the term isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in naturally occurring alkaloids including papaverine. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. The isoquinoline ring in these natural compound derives from the aromatic amino acid tyrosine. SDS of cas: 1532-97-4.

Li, Xuefei;Gao, Xing;He, Chun-Yang;Zhang, Xingang research published 《 Using Chlorotrifluoroethane for Trifluoroethylation of (Hetero)aryl Bromides and Chlorides via Nickel Catalysis》, the research content is summarized as follows. A nickel-catalyzed reductive cross-coupling between industrial chem. CF3CH2Cl and (hetero)aryl bromides and chlorides was reported. The reaction was synthetically simple without the preparation of arylmetals and exhibits high functional group tolerance. The utility of this protocol was demonstrated by the late-stage modification of pharmaceuticals, providing a facile route for medicinal chem.

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., SDS of cas: 1532-97-4

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Li, Lifan team published research on Tetrahedron Letters in 2022 | 1532-97-4

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Product Details of C9H6BrN

Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Product Details of C9H6BrN.

Li, Lifan;Song, Xuyan;Qi, Mei-Fang;Sun, Bing research published 《 Weak Bronsted base-promoted photoredox catalysis for C-H alkylation of heteroarenes mediated by triplet excited diaryl ketone》, the research content is summarized as follows. A weak Bronsted base-promoted photoredox catalysis had been developed for the direct C-H α-alkylation of heteroarenes with cyclic and acyclic ethers. The high efficiency of this strategy was demonstrated by the mild reaction conditions, broad substrate scope, economical reagents and high regioselectivity. With air as the sole oxidant, a set of alkylated heteroarenes were accessed smoothly. This strategy was also applied for late-stage functionalization of valuable vitamin E nicotinate and loratadine.

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Product Details of C9H6BrN

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Li, Haoxi team published research on ACS Chemical Neuroscience in 2022 | 1532-97-4

Application In Synthesis of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Application In Synthesis of 1532-97-4.

Li, Haoxi;Mirabel, Rosa;Zimmerman, Joseph;Ghiviriga, Ion;Phidd, Darian K.;Horenstein, Nicole;Urs, Nikhil M. research published 《 Structure-Functional Selectivity Relationship Studies on A-86929 Analogs and Small Aryl Fragments toward the Discovery of Biased Dopamine D1 Receptor Agonists》, the research content is summarized as follows. Dopamine regulates normal functions such as movement, reinforcement learning, and cognition, and its dysfunction has been implicated in multiple psychiatric and neurol. disorders. Dopamine acts through D1- (D1R and D5R) and D2-class (D2R, D3R, and D4R) receptors and activates both G protein- and β-arrestin-dependent signaling pathways. Current dopamine receptor-based therapies are used to ameliorate motor deficits in Parkinson’s disease or as antipsychotic medications for schizophrenia. These drugs show efficacy for ameliorating only some symptoms caused by dopamine dysfunction and are plagued by debilitating side effects. Studies in primates and rodents have shown that shifting the balance of dopamine receptor signaling toward the arrestin pathway can be beneficial for inducing normal movement, while reducing motor side effects such as dyskinesias, and can be efficacious at enhancing cognitive function compared to balanced agonists. Several structure-activity relationship (SAR) studies have embarked on discovering β-arrestin-biased dopamine agonists, focused on D2 partial agonists, noncatechol D1 agonists, and mixed D1/D2R dopamine receptor agonists. Here, we describe an SAR study to identify novel D1R β-arrestin-biased ligands using A-86929, a high-affinity D1R catechol agonist, as a core scaffold to identify chem. motifs responsible for β-arrestin-biased activity at both D1 and D2Rs. Most of the A-86929 analogs screened were G protein-biased, but none of them were exclusively arrestin-biased. Addnl., various small-fragment mol. probes displayed weak bias toward the β-arrestin pathway. Continued in-depth SFSR (structure-functional selectivity relationship) studies informed by structure determination, mol. modeling, and mutagenesis studies will facilitate the discovery of potent and efficacious arrestin-biased dopamine receptor ligands.

Application In Synthesis of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Li, Haoran team published research on Tetrahedron Letters in 2021 | 1532-97-4

Synthetic Route of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Synthetic Route of 1532-97-4.

Li, Haoran;Huang, Hai-Yun;Roisnel, Thierry;Doucet, Henri research published 《 Regiocontrolled palladium-catalyzed direct C2-arylation of a difluorobenzo[d]imidazole》, the research content is summarized as follows. Conditions for the regioselective palladium-catalyzed direct arylation of a 6,7-difluorobenzo[d]imidazole using aryl bromides ArBr (Ar = 4-chlorophenyl, pyridin-4-yl, naphth-2-yl, etc.) as the coupling partners are described. The site selectivity of the arylation was found to be in favor of the C2-carbon of the difluorobenzo[d]imidazole; whereas the difluoro-substituted ring remained untouched, even in the presence of an excess of aryl bromide. This method tolerates a variety of substituents at para-, meta- and ortho-positions on the aryl bromide and also N-containing heteroaryl bromides.

Synthetic Route of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Leonard, David K. team published research on ChemSusChem in 2022 | 1532-97-4

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Quality Control of 1532-97-4

Isoquinoline can crystallizes in platelets that have a low solubility in water but dissolve well in ethanol, acetone, diethyl ether, carbon disulfide, and other common organic solvents. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is also soluble in dilute acids as the protonated derivative. Quality Control of 1532-97-4.

Leonard, David K.;Ryabchuk, Pavel;Anwar, Muhammad;Dastgir, Sarim;Junge, Kathrin;Beller, Matthias research published 《 A Convenient and Stable Heterogeneous Nickel Catalyst for Hydrodehalogenation of Aryl Halides Using Molecular Hydrogen》, the research content is summarized as follows. In this study, a nickel-based catalyst supported on titania (Ni-phen@TiO2-800) was prepared and used as a safe alternative to pyrophoric Raney-nickel. The catalyst was prepared in a straightforward fashion by deposition of nickel(II)/1,10-phenanthroline on titania, followed by pyrolysis. The catalytic material, which was characterized by SEM, TEM, XRD and XPS, consisted of nickel nanoparticles covered with N-doped carbon layers. By using design of experiments (DoE), this nanostructured catalyst was found to be proficient for the facile and selective hydrodehalogenation of a diverse range of substrates bearing C-I, C-Br, or C-Cl bonds afforded aromatic hydrocarbons R-H [R = 1-naphthyl, 4-H2NC6H4, 4-CO2MeC6H4, etc.] (>30 examples). The practicality of this catalyst system was demonstrated by the dehalogenation of environmentally hazardous and polyhalogenated substrates atrazine, tetrabromobisphenol A, tetrachlorobenzene and a polybrominated di-Ph ether (PBDE).

1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Quality Control of 1532-97-4

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Dong, Jianyang team published research on Organic Letters in 2021 | 1532-97-4

HPLC of Formula: 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

In a broader sense, the term isoquinoline is used to make reference to isoquinoline derivatives. 1-Benzylisoquinoline is the structural backbone in naturally occurring alkaloids including papaverine. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. The isoquinoline ring in these natural compound derives from the aromatic amino acid tyrosine. HPLC of Formula: 1532-97-4.

Dong, Jianyang;Liu, Jianhua;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin research published 《 Metal-, Photocatalyst-, and Light-Free Minisci C-H Acetylation of N-Heteroarenes with Vinyl Ethers》, the research content is summarized as follows. Herein, a mild, operationally simple method for Minisci C-H acetylation of N-heteroarenes using vinyl ethers as robust, inexpensive acetyl sources was reported. The reactions do not require a conventional photocatalysis, electrocatalysis, metal catalysis, light activation, or high temperature This method is thus significantly more sustainable than previously reported methods in terms of cost, reagent toxicity, and waste generation. This protocol can be expected to obtain medically relevant mols. from abundant feedstock materials.

HPLC of Formula: 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Dong, Jianyang team published research on Chemical Communications (Cambridge, United Kingdom) in 2020 | 1532-97-4

Product Details of C9H6BrN, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Product Details of C9H6BrN.

Dong, Jianyang;Yue, Fuyang;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin research published 《 Visible-light-mediated photoredox minisci C-H alkylation with alkyl boronic acids using molecular oxygen as an oxidant》, the research content is summarized as follows. A protocol for direct visible-light-mediated Minisci C-H alkylation reactions of heteroarenes, e.g., 4,6-dimethylpyrimidine with alkyl boronic acids RB(OH)2 (R = CH2CH3, C6H5, cyclohexyl, etc.) using mol. oxygen as the sole oxidant has been described. This mild protocol uses an inexpensive, green oxidant, permits efficient functionalization of various N-heteroarenes with a broad range of primary and secondary alkyl boronic acids; and is scalable to the gram level. The practicality and sustainability of the protocol by preparing or functionalizing several pharmaceuticals and natural products have been demonstrated.

Product Details of C9H6BrN, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Dong, Jianyang team published research on Advanced Synthesis & Catalysis in 2020 | 1532-97-4

Name: 4-Bromoisoquinoline, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline is a heterocyclic aromatic organic compound. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is a structural isomer of quinoline. Isoquinoline and quinoline are benzopyridines, which are composed of a benzene ring fused to a pyridine ring. Name: 4-Bromoisoquinoline.

Dong, Jianyang;Wang, Xiaochen;Song, Hongjian;Liu, Yuxiu;Wang, Qingmin research published 《 Photoredox-Catalyzed Redox-Neutral Minisci C-H Formylation of N-Heteroarenes》, the research content is summarized as follows. A protocol for redox-neutral Minisci C-H formylation of N-heteroarenes using 1,3-dioxoisoindolin-2-yl 2,2-diethoxyacetate as a formyl equivalent at room temp was reported. This scalable benchtop protocol offered a distinct advantage over traditional reductive carbonylation and Minisci C-H formylation methods in not requiring the use of carbon monoxide, pressurized gas, a stoichiometric reductant, or a stoichiometric oxidant.

Name: 4-Bromoisoquinoline, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Ding, Licheng team published research on Tetrahedron Letters in 2020 | 1532-97-4

Synthetic Route of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline’s properties: Isoquinoline is a colorless hygroscopic liquid at temperatures above its melting point with a penetrating, 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. unpleasant odor. Impure samples can appear brownish, as is typical for nitrogen heterocycles. Synthetic Route of 1532-97-4.

Ding, Licheng;Han, Shuaijun;Chen, Xiaoyu;Li, Linlin;Li, Jingya;Zou, Dapeng;Wu, Yangjie;Wu, Yusheng research published 《 An efficient protocol for the synthesis of monofluoroalkylated (hetero)arenes via Pd-catalyzed α-(hetero)arylation of α-fluoroketones with (hetero)aryl bromides》, the research content is summarized as follows. An efficient synthesis of monofluoroalkylated N-heteroarenes using α-fluoroketones as monofluoroalkyl reagents was developed. A variety of novel α-(hetero)aryl-α-fluoroketones and monofluoroalkylated N-heteroarenes were obtained in moderate to good yields. Notable advantages of this protocol include a low catalyst loading, easily prepared monofluoroalkyl reagents and wide substrate scope.

Synthetic Route of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

 

Devi, Lalita team published research on Chemical Communications (Cambridge, United Kingdom) in 2022 | 1532-97-4

Quality Control of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Isoquinoline’s properties: Isoquinoline is a colorless hygroscopic liquid at temperatures above its melting point with a penetrating, 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. unpleasant odor. Impure samples can appear brownish, as is typical for nitrogen heterocycles. Quality Control of 1532-97-4.

Devi, Lalita;Kumar, Prashant;Kant, Ruchir;Rastogi, Namrata research published 《 Exploiting the umpolung reactivity of diazo groups: direct access to triazolyl-azaarenes from azaarenes》, the research content is summarized as follows. The present work documents electrophilic substitution of azaarenes, mainly isoquinolines, with hypervalent iodine diazo reagents (HIDR) followed by formal [3+2]-dipolar cycloaddition in a tandem fashion. Other azaarenes viz. pyridines and phenanthridines too could be successfully used in the reaction. The methodol. capitalizes on the umpolung nature of α-aryliodonio diazo compounds for installing a nucleophile, i.e. azaarene, at their α-position. Subsequent ylide formation and intramol. 1,5-cyclization furnished 4,3-fused 1,2,4-triazolyl-azaarenes in good yields. The reaction is notable for its mild conditions, operational simplicity and fairly general scope.

Quality Control of 1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.

4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., 1532-97-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem