1109230-25-2, 5-Bromo-3,4-dihydroisoquinolin-1(2H)-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5-bromo-3,4-dihydroisoquinoline-1(2H)-one (1.05 g, 4.64 mmol) was dissolved in concentrated sulfuric acid in a 50 mL single-mouth bottle(15mL), at -10C,KNO3 (1.04 g, 7.00 mmol) was slowly added, the solution was pale yellow and stirred for 1.0 h. After warming to room temperature, the reaction was continued for 3.0 h.The reaction was monitored by TLC, poured into ice water and extracted with EA (15 mL¡Á3).Dry over anhydrous sodium sulfate,Concentrate, silica gel column chromatography, rinse with PE/EA=20/1-10/1,Obtained white solid 0.42g, yield 33%,, 1109230-25-2
The synthetic route of 1109230-25-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Lin Xinglong; Xie Hongming; Hu Yangxiao; Li Shiguang; Zhang Yingjun; Tan Yumei; Yuan Mingyun; (124 pag.)CN108948019; (2018); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem