Tag: M.W=100-150

Hirai, Takahiro published the artcileEsterification of Tertiary Amides: Remarkable Additive Effects of Potassium Alkoxides for Generating Hetero Manganese-Potassium Dinuclear Active Species, Quality Control of 5961-59-1, the main research area is esterification tertiary amide potassium alkoxide manganese dinuclear catalyst; amides; esterification; manganese; reaction intermediates; reaction mechanisms.

A catalyst system of mononuclear manganese precursor combined with potassium alkoxide served as a superior catalyst compared with our previously reported manganese homodinuclear catalyst (defined within) for esterification of not only tertiary aryl amides, but also tertiary aliphatic amides. On the basis of stoichiometric reactions of a manganese precursor and potassium alkoxide salt, kinetic studies, and d. functional theory (DFT) calculations, we clarified a plausible reaction mechanism in which in situ generated manganese-potassium heterodinuclear species cooperatively activates the carbonyl moiety of the amide and the OH moiety of the alcs. We also revealed details of the reaction mechanism of our previous manganese homodinuclear system, and we found that the activation free energy (ΔG≠) for the manganese-potassium heterodinuclear complex catalyzed esterification of amides is lower than that for the manganese homodinuclear system, which was consistent with the exptl. results. We further applied our catalyst system to deprotect the acetyl moiety of primary and secondary amines.

Chemistry – A European Journal published new progress about Amides, aliphatic Role: RCT (Reactant), RACT (Reactant or Reagent) (tertiary). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Quality Control of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Sadamitsu, Yuta published the artcileKolbe-Schmitt type reaction under ambient conditions mediated by an organic base, Computed Properties of 151-10-0, the main research area is salicylic acid preparation; resorcinol carbon dioxide DBU Kolbe Schmitt type reaction.

The combined use of an organic base for resorcinols realized a Kolbe-Schmitt type reaction under ambient conditions. When resorcinols (3-hydroxyphenol derivatives) were treated with DBU under a carbon dioxide atm., nucleophilic addition to carbon dioxide proceeded to afford the corresponding salicylic acid derivatives in high yields.

Chemical Communications (Cambridge, United Kingdom) published new progress about Hydroxycarboxylic acids Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Computed Properties of 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Nishino, Kota published the artcilePalladium(II)/Copper(II)-Catalyzed C-H Sulfidation or Selenation of Arenes Leading to Unsymmetrical Sulfides and Selenides, Category: isoquinoline, the main research area is sulfide selenide preparation; arene sulfidation selenation palladium copper catalyst.

A novel palladium(II)/copper(II)-catalyzed sulfidation of the C-H bond in electron-rich arenes and in pentafluorobenzene with disulfides was developed. This catalytic system can be used to efficiently produce various types of either unsym. aryl sulfides or alkyl aryl sulfides. The present protocol could also be applied to the direct preparation of unsym. aryl selenides via C-H selenation.

European Journal of Organic Chemistry published new progress about Aromatic compounds, disulfides Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wang, Xin-Xing published the artcileMetal-and oxidant-free electrochemical synthesis of aryl sulfides, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is aryl sulfide preparation electrochem; arene disulfide sulfidation.

A metal- and oxidant-free electrochem. synthesis of aryl sulfides was developed through a C-H sulfidation reaction of arenes and disulfides. Compared with traditional organic synthesis methods, this direct electrochem. approach efficiently generates aryl sulfides under catalyst- and oxidant-free conditions with the superiorities of wide substrate compatibility, mild reaction condition and waster free. At room temperature, various aryl thiols could be transformed smoothly in an undivided cell. Based on cyclic voltammetry (CV) and control experiments, the possible reaction mechanism was also proposed. The gram-scale synthesis emphasizes the practicability of this electrochem. strategy.

Journal of the Electrochemical Society published new progress about Aromatic compounds, disulfides Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zhen, Long published the artcileSynthesis of Thiocarbamoyl Fluorides and Isothiocyanates Using CF3SiMe3 and Elemental Sulfur or AgSCF3 and KBr with Amines, Recommanded Product: 4-Methoxy-N-methylaniline, the main research area is thiocarbamoyl fluoride isothiocyanate preparation amine sulfur trifluoromethyl trimethylsilane.

Reactions of thiocarbonyl fluoride derived from cheap, readily available, and widely used CF3SiMe3, elemental sulfur, and KF with secondary amines and primary amines at room temperature in THF provided a wide variety of thiocarbamoyl fluorides and isothiocyanates in moderate to excellent yields, resp. The two reactions show broad substrate scope and good functional group tolerance. Moreover, AgSCF3 reacts with secondary/primary amines under KBr at room temperature, affording quant. thiocarbamoyl fluorides/isothiocyanates, which feature late-stage application.

Organic Letters published new progress about Fluorides Role: SPN (Synthetic Preparation), PREP (Preparation) (thiocarbamoyl). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Recommanded Product: 4-Methoxy-N-methylaniline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Ranjit, Rosa published the artcileBiological and chemical analysis of five selected lichen species from Sagarmatha National Park of Nepal, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is lichen species Antioxidant Antibacterial alpha amylase metabolites Nepal.

The purpose of this study was to profile the chem. constituents and biol. activities of methanol extract of five lichens; Lobaria japonica, Lobaria retigera, Heterodermia leucomela, Heterodermia speciosa and Ramalina spp. collected from Sagarmatha National Park, Solukhumbu District, Nepal. Total phenolic content was evaluated by Folin Ciocalteu method while total flavonoid content was evaluated by aluminum chloride colorimetric method. Antioxidant activity was evaluated by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay and α-amylase inhibitory activity was evaluated by starch-iodine method. Antibacterial activity was evaluated by agar-well diffusion method. Similarly, the highest flavonoid content was observed in L. retigera and lowest in Ramalina spp. The highest DPPH radical scavenging activity was shown by L. retigera and lowest by H. speciosa. The lichens possessed high antimicrobial properties against E. coli, S. aureus and B. subtilis. Metabolites profiling of selected three lichens species by Gas Chromatog.-Mass Spectrometry revealed the presence of atraric acid, Me haematomate, orcinol and Me everniate as the major components. Among the five lichens, L. japonica and L. retigera were found to possess potent biol. activities as well as higher phenolic and flavonoid contents. These lichens can be further studied and processed for the com. production of polyphenols.

Tropical Journal of Natural Product Research published new progress about Flavanoids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wang, Yanru published the artcileNonmetal-catalyzed hydroamination of ynamides with amines, Application In Synthesis of 5961-59-1, the main research area is alkylamino phenylimine preparation; aniline ynamide triflic acid catalyst regioselective hydroamination; alkenyl diamine preparation; secondary amine ynamide triflic acid catalyst regioselective diastereoselective hydroamination.

The first metal-free catalytic regioselective hydroamination of ynamides with primary and secondary amines were achieved by using TfOH as the catalyst under mild reaction conditions. This appealing strategy provided the corresponding N-arylimines and ethene-1,1-diamines in good to excellent yields with wide functional group tolerance. Furthermore, their applications in 2-aminoindole synthesis was presented.

Organic Chemistry Frontiers published new progress about Alkenes Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Application In Synthesis of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Gevorgyan, Ashot published the artcileFormal C-H Carboxylation of Unactivated Arenes, Safety of 1,3-Dimethoxybenzene, the main research area is carboxyl unactivated arene preparation green chem regioselective; unactivated arene carbon dioxide carboxylation copper catalyst; carbon dioxide aryl boronate carboxylation copper catalyst; C−H activation; carbon dioxide; carboxylation; green solvent; late-stage functionalization.

A formal C-H carboxylation of unactivated arenes e.g., I using CO2 in green solvents is described. The present strategy combines a sterically controlled Ir-catalyzed C-H borylation followed by a Cu-catalyzed carboxylation of the in situ generated organoboronates. The reaction is highly regioselective for the C-H carboxylation of unactivated arenes e.g., I (1,3-disubstituted and 1,2,3-trisubstituted benzenes, 1,2- or 1,4-sym. substituted benzenes, fluorinated benzenes and different heterocycles). The developed methodol. was applied to the late-stage C-H carboxylation of com. drugs and ligands.

Chemistry – A European Journal published new progress about Aromatic carboxylic acids Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Yuan, Tao published the artcileCeramic boron carbonitrides for unlocking organic halides with visible light, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is boron carbonitride preparation surface structure; aryl halide boron carbonitride photocatalyst hydrodehalogenation; aromatic hydrocarbon preparation; arene aryl halide boron carbonitride photocatalyst cross coupling arylation; biaryl preparation; haloarene sodium sulfinate boron carbonitride photocatalyst cross coupling sulfonylation; arylsulfone preparation.

Here, boron carbonitride (BCN) ceramics were such a system and can reduce organic halides, including (het)aryl and alkyl halides, with visible light irradn was reported. Cross-coupling of halides to afford new C-H, C-C, and C-S bonds was proceeded at ambient reaction conditions. Hydrogen, (het)aryl, and sulfonyl groups were introduced into the arenes and heteroarenes at the designed positions by means of mesolytic C-X (carbon-halogen) bond cleavage in the absence of any metal-based catalysts or ligands. BCN was used not only for half reactions, like reduction reactions with a sacrificial agent, but also redox reactions through oxidative and reductive interfacial electron transfer. The BCN photocatalyst showed tolerance to different substituents and conserved activity after five recycles. The apparent metal-free system opened new opportunities for a wide range of organic catalysts using light energy and sustainable materials, which were metal-free, inexpensive and stable.

Chemical Science published new progress about Aromatic compounds, sulfones Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Nassar, Youssef published the artcileA short route to access oxaspiro[n,3,3]propellanes, Quality Control of 151-10-0, the main research area is oxo propynyl cyclohexane carboxylate silver bismuth catalyzed cyclization; oxaspirocyclopropane propellane preparation; oxaspiro lactone propellane preparation.

Novel access to oxaspiro[n,3,3]propellanes was developed from bicyclic lactones directly prepared by a photochem. hydroxymethylation or alternatively by a three-step sequence. The presence of addnl. hydroxy- and propargylic groups, a second cyclization catalyzed by silver or bismuth salts, led to the propellane structure which was finally transformed into spiranic derivatives by a Simmons-Smith reaction or condensation with α-ketoesters.

Organic & Biomolecular Chemistry published new progress about Bicyclic compounds, lactones Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Quality Control of 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem