Tag: M.W=150-200

Li, Chenchen published the artcileOxidation of Alkynyl Boronates to Carboxylic Acids, Esters, and Amides, SDS of cas: 104-01-8, the main research area is carboxylate ester amide preparation alkynyl boronate oxidation; alkynes; boron; carboxylic acids; oxidation; synthetic methods.

A general efficient protocol was developed for the synthesis of carboxylic acids, esters, and amides through oxidation of alkynyl boronates, generated directly from terminal alkynes. This protocol represents the first example of C(sp)-B bond oxidation This approach displays a broad substrate scope, including aryl and alkyl alkynes, and exhibits excellent functional group tolerance. Water, primary and secondary alcs., and amines are suitable nucleophiles for this transformation. Notably, amino acids and peptides can be used as nucleophiles, providing an efficient method for the synthesis and modification of peptides. The practicability of this methodol. was further highlighted by the preparation of pharmaceutical mols.

Angewandte Chemie, International Edition published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, SDS of cas: 104-01-8.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Qiao, Huihao published the artcilePalladium-Catalyzed Direct Ortho-C-H Selenylation of Benzaldehydes Using Benzidine as a Transient Directing Group, Application In Synthesis of 86-51-1, the main research area is palladium catalyzed ortho selenylation benzaldehyde; diarylselenide preparation selenylation benzidine transient directing group.

Benzidine was found to be a novel transient directing group to enable Pd-catalyzed direct selenylation of inert C(sp2)-H bonds of benzaldehydes. Diverse diarylselenides were readily constructed in high efficiency and satisfactory yields with good functional group tolerance. The practical usage of the method was further demonstrated by enlarged reaction to gram scale and application in the facile access to two selenoxanthenes and one fluorescent probe.

Organic Letters published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Application In Synthesis of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Gangu, Kranthi Kumar published the artcileCatalytic activity of supra molecular self-assembled Nickel(II) coordination complex in synthesis of indeno-pyrimidine derivatives, SDS of cas: 86-51-1, the main research area is crystal structure nickel bipyridine pyridinedicarboxylate preparation catalyst indenopyrimidine green; aldehyde indanedione reaction guanidinium catalyst green nickel bipyridine pyridinedicarboxylate.

A supra mol. self-assembled Ni(II) coordination complex, formulated as [Ni2(2,6-pydc)2(μ-4,4’bpy)(H2O)4]·4H2O (2,6-pydcH2 = pyridine-2,6-dicarboxylic acid, 4,4’bpy = 4,4′-bipyridine) was synthesized under hydrothermal condition and characterized by single crystal x-ray diffraction, elemental anal., FTIR, powder x-ray diffraction, and thermo gravimetric anal. Single crystal x-ray diffraction anal. reveals that the complex crystallizes in the monoclinic space group P21/c with a 10.5237(6), b 20.1966(10), c 7.2366(4) Å, β = 106.96(1°) and displays a 3-dimensional supramol. network through H bond and C-H···π, C-O···π interactions. Ni(II) metal species in the structure possess coordinately unsaturated centers, which exhibited viable catalytic properties in the synthesis of eight different indeno-pyrimidine derivatives through 1-pot reaction involving benzaldehydes, indane-1,3-dione and guanidinium chloride in a green approach. With the reaction achieved in 15 min time interval in EtOH in excellent yields (87-98%), plus the good recyclability (up to 6 times) provides advantage to this complex in heterogeneous catalysis.

Polyhedron published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, SDS of cas: 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Jureddi, Santhosh Kumar published the artcileSustainable Cs2O/ZrO2 oxide catalyst for the synthesis of 1,4-dihydropyridine analogues, Category: isoquinoline, the main research area is zirconia supported cesium oxide nanocatalyst preparation thermal stability; malononitrile acetylene dicarboxylate dimethylaniline benzaldehyde heterogeneous catalyst multicomponent reaction; amino cyano diphenyl dihydropyridine dicarboxylate preparation green chem.

Cesium oxide loaded on zirconia (Cs2O/ZrO2) was prepared as heterogeneous catalyst for the synthesis of 1,4-dihydropyridine analogs via a one-pot, multi-component reaction involving substituted benzaldehydes, malononitrile, dimethylaniline and dimethylacetylene dicarboxylate with good to excellent product yields (83 to 97%). The notable benefits of this facile approach was the use of ethanol as solvent and products were obtained in excellent yields with shorter reaction times. Catalyst was fully reusable with minor loss of activity up to six cycles. While, P-XRD, TEM and SEM anal. performances were revealed for the structural interpretation of Cs2O/ZrO2, the identity of products were established and confirmed by various spectral (1H NMR, 13C NMR, FT-IR and HRMS) techniques.

Journal of Applicable Chemistry (Lumami, India) published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Mirjalili, Bi Bi Fatemeh published the artcileFe3O4@NCs/BF0.2: A magnetic bio-based nanocatalyst for the synthesis of 2,3-dihydro-1H-perimidines, SDS of cas: 86-51-1, the main research area is dihydro perimidine preparation green chem; diaminonaphthalene aldehyde cyclization iron nanocatalyst.

Fe3O4@NCs/BF0.2 as a green, bio-based, eco-friendly, and recyclable catalyst was synthesized and characterized using Fourier-transform IR spectroscopy (FT-IR), vibrating sample magnetometer (VSM), X-ray diffraction (XRD), X-ray fluorescence (XRF), Brunauer-Emmett-Teller (BET), field emission SEM (FESEM), transmission electron microscopy (TEM), and thermal gravimetric anal. (TGA) techniques. Fe3O4@NCs/BF0.2 was employed for the synthesis of 2,3-dihydro-1H-perimidine derivatives I (R = 4-OCH3, 2-NO2, 4-N(CH3)2, etc.) via a reaction of 1,8-diaminonaphthalene with various aldehydes RC6H4CHO at room temperature under solvent-free conditions. The present procedure offers several advantages including a short reaction time, excellent yields, easy separation of catalyst, and environmental friendliness.

Journal of the Chinese Chemical Society (Weinheim, Germany) published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, SDS of cas: 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Farahnak Zarabi, Maryam published the artcileUltrasound Promoted Synthesis of Benzo[a]pyrano-[2,3-c]phenazines Using Multisulfonic Acid Hyperbranched Polyglycerol Functionalized Graphene Oxide as a Novel and Reusable Catalyst, Synthetic Route of 86-51-1, the main research area is benzopyranophenazine preparation green chem ultrasound; hydroxynaphthalenedione phenylenediamine aldehyde malononitrile cyclization polyglycerol graphene oxide nanocatalyst.

A green and rapid sonochem. research to preparation of the benzo[a]-pyrano[2,3-c]phenazines I [R = Ph, 4-(dimethylamino)phenyl, 2,3-dimethoxyphenyl, etc.] was carried out through a four-component reaction of 2-hydroxynaphthalene-1,4-dione, o-phenylenediamine, aldehydes RCHO, and malononitrile by using multisulfonic acid hyperbranched polyglycerol modified graphene oxide as an effective and recyclable catalyst. This procedure has a number of advantages such as: excellent yields, short reaction times and green conditions. In addition, the catalyst could be recovered easily and reused several times without any considerable loss of its catalytic activity.

Polycyclic Aromatic Compounds published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Synthetic Route of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Shirzaei, Farhad published the artcile[(EtO)3Si(CH2)3NH3+][CH3COO-] as a novel basic ionic liquid catalyzed green synthesis of new 2-(phenylsulfonyl)-1H-benzo[a]pyrano[2,3-c]phenazin-3-amine derivatives, Category: isoquinoline, the main research area is phenylsulfonyl benzo pyranophenazinamine preparation green chem; hydroxynaphthalenedione phenylenediamine aldehyde phenylsulfonyl acetonitrile cyclocondensation ionic liquid catalyst.

An efficient, one-pot procedure for the preparation of new 2-(phenylsulfonyl)-1H-benzo[a]pyrano[2,3-c]phenazin-3-amine derivatives I (R = Ph, 4-bromophenyl, 3,4,5-trimethoxyphenyl, etc.) and II from four-component condensation reaction of 2-hydroxynaphthalene-1,4-dione, o-phenylenediamine, aromatic aldehydes RCHO and 2,3-dihydro-1H-indole-2,3-dione, and (phenylsulfonyl)acetonitrile in the presence of [(EtO)3Si(CH2)3NH3+][CH3COO-] as a novel basic ionic liquid as catalyst under solvent-free conditions is described. Simple procedure, high yields, short reaction times and an environmentally benign method are advantages of this protocol. The [(EtO)3Si(CH2)3NH3+][CH3COO-] can be recovered and reused several times without loss of its activity.

Journal of Molecular Structure published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Shirzaei, Farhad published the artcileBasic ionic liquid, 2-hydroxyethylammonium formate, catalyzed one-pot synthesis of novel 2-(phenylsulfonyl)-1H-benzo[a]pyrano[2,3-c]phenazin-3-amine derivatives, Formula: C9H10O3, the main research area is phenylsulfonyl benzopyranophenazinamine preparation green chem; hydroxynaphthalenedione benzenediamine arylaldehyde phenylsulfonyl acetonitrile condensation ionic liquid catalyst.

A new, one-pot, efficient, and four-component condensation of 2-hydroxynaphthalene-1,4-dione, benzene-1,2-diamine, arylaldehydes RCHO (R = Ph, 4-bromophenyl, 3,4,5-trimethoxyphenyl, etc.) and 2,3-dihydro-1H-indole-2,3-dione and (phenylsulfonyl)acetonitrile in the presence of a reusable basic ionic liquid, 2-hydroxyethylammonium formate, as catalyst for the synthesis of novel 2-(phenylsulfonyl)-1H-benzo[a]pyrano[2,3-c]phenazin-3-amine derivatives I and II under solvent-free conditions at 80°C was described. A simple reaction and work-up procedure for the synthesis of new un-known compounds I and II using a green and reusable ionic liquid as catalyst under solvent-free and thermal conditions was reported. The easy preparation of ionic liquid was superiority of the mentioned basic ionic liquid This protocol has various advantages such as short reaction times, excellent yields, no column chromatog., and green environmentally safe media.

Research on Chemical Intermediates published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Formula: C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Gangu, Kranthi Kumar published the artcilePreparation and characterisation of new Ti/Fluorapatite/MWCNTs ternary nanocomposite and its catalytic activity in the synthesis of pyrazolo[3,4-b]quinoline moieties, COA of Formula: C9H10O3, the main research area is titania fluorapatite multiwalled carbon nanotube nanocomposite catalyst preparation; pyrazoloquinolone green preparation titania fluoroapatite nanocomposite catalyst; benzaldehyde dimedone aminomethylphenylpyrazole three component cyclocondensation titanium nanocatalyst.

A new ternary nanocomposite (Ti/FAp/MWCNTs) constituting titania, fluorapatite and multiwalled carbon nanotubes was prepared First, the fluorapatite (FAp) nanostructures were developed using glutamic acid as the crystal growth modifier; then it reacted with functionalized MWCNT sand TiO2 via sonication in ether. The Powder XRD, FT-IR and microscopic anal. (SEM and TEM) of the new nanocomposite, Ti/FAp/MWCNTs revealed three phases. TiO2 and FAp particle sizes were between 50-60 nm and 40-60 nm diameter, resp. This new ternary nanocomposite’s catalytic ability was examined in the three-component condensation of aromatic aldehydes, dimedone and 5-amino-3-methyl-1-phenylpyrazole to synthesize pyrazolo[3,4-b]quinolone derivatives I [R = 2,3-(OMe)2, 2-F, 2-NO2, 3-Br, 3-Cl] in impressive yields (91-95%) with short reaction times (ca.15 min) in the green solvent EtOH at room temperature The synergy between the Lewis acidic and basic sites contributed to the nanocomposite’s effectiveness. Recyclability with consistent activity (>5 times) was the added advantage of the Ti/FAp/MWCNTs nanocomposite.

Materials Today Communications published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, COA of Formula: C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Harutyunyan, A. A. published the artcileOne-Pot Three-Component Condensations of 2,6-Diaminopyrimidin-4(3H)-one, Aromatic Aldehydes, and Naphthols. Synthesis of Isomeric Benzochromeno[2,3-d]pyrimidines, Synthetic Route of 86-51-1, the main research area is benzochromenopyrimidine preparation; diaminopyrimidinone benzaldehyde naphthol three component cyclocondensation.

One-pot three-component reactions of 2,6-diaminopyrimidin-4-(3H)-one with aromatic aldehydes and 1- or 2-naphthol afforded benzo[7,8]chromeno[2,3-d]pyrimidine I (R = 3-Br, 3-NO2, 4-PhCH2O, etc.) and benzo[5,6]chromeno[2,3-d]pyrimidine II (R1 = H, 2-F, 2-OH-3-OMe, etc.) derivatives, resp. In both cases, the heterocyclization involved substitution of the 6-amino group of 2,6-diaminopyrimidin-4-(3H)-one by hydroxy group of naphthol and closure of 4H-pyran ring, whereas no alternative benzopyrimidoquinoline derivatives were formed.

Russian Journal of Organic Chemistry published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Synthetic Route of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem