Month: December 2022

Yang, Jie published the artcileSurface modification of core-shell structured ZIF-67@Cobalt coordination compound to improve the fire safety of biomass aerogel insulation materials, Quality Control of 1455-77-2, the main research area is zeolitic imidazolate framework cobalt coordination compound surface modification; biomass aerogel fire safety thermal insulation property.

Biomass materials are considered to be excellent candidates to replace petroleum-based materials, but inherent flammability limits their applications. In this work, biomass aerogel (BA) was prepared by freeze-drying method from sodium alginate (SA) and polyvinyl alc. (PVA). To improve fire safety of BAs, a core-shell structured ZIF-67@cobalt coordination compound was successfully synthesized, which was surface functionalized by 3,5-diamino-1,2,4-triazole and 9,10-dihydro-9-oxo-10-phospho-diphenyl-10-oxide (DOPO), named as DOPO-NH2-ZIF-67. The addition of DOPO-NH2-ZIF-67 (2 wt%) outstandingly improved fire safety of BA, in contrast to neat BA, peak heat release rate, peak smoke production rate, and total smoke production were reduced by 66.6%, 85.10%, and 72.76%, resp. Furthermore, the incorporation of ZIF-67 and its derivatives has no adverse effect on the thermal insulation performance of BA composites and significantly improved their compressive strength from 0.27 MPa to 1.76 MPa. Preparation of core-shell structured ZIFs rich in active groups furnishes a conceivable way to synthesize an effective flame retardant, and a prospective method for the fabrication of aerogel insulation materials with green and economical additive-free technol. is proposed.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Aerogels. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Quality Control of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Forrez, Ilse published the artcileBiogenic metals for the oxidative and reductive removal of pharmaceuticals, biocides and iodinated contrast media in a polishing membrane bioreactor, Name: Diatrizoic Acid, the main research area is biogenic metal oxidation reduction pharmaceutical biocide polishing membrane bioreactor; biocide iodinated contrast media.

Pharmaceutical and personal care products, biocides and iodinated contrast media (ICM) are persistent compounds, which appear in ng to μg L-1 in secondary effluents of sewage treatment plants (STPs). In this work, biogenic metals manganese oxides (BioMnOx) and bio-palladium (Bio-Pd) were applied in lab-scale membrane bioreactors (MBR) as oxidative and reductive technologies, resp., to remove micropollutants from STP-effluent. From the 29 substances detected in the STP-effluent, 14 were eliminated in the BioMnOx-MBR: ibuprofen (>95%), naproxen (>95%), diuron (>94%), codeine (>93%), N-acetyl-sulfamethoxazole (92%), chlorophene (>89%), diclofenac (86%), mecoprop (81%), triclosan (>78%), clarithromycin, (75%), iohexol (72%), iopromide (68%), iomeprol (63%) and sulfamethoxazole (52%). The putative removal mechanisms were the chem. oxidation by BioMnOx and/or the biol. removal by Pseudomonas putida and associated bacteria in the enriched biofilm. Yet, the removal rates (highest value: 2.6 μg diclofenac L-1 d-1) need to improve by a factor 10 in order to be competitive with ozonation. ICM, persistent towards oxidative techniques, were successfully dehalogenated with a novel reductive technique using Bio-Pd as a nanosized catalyst in an MBR. Iomeprol, iopromide and iohexol were removed for >97% and the more recalcitrant diatrizoate for 90%. The conditions favorable for microbial H2-production enabling the charging of the Pd catalyst, were shown to be important for the removal of ICM. Overall, the results indicate that Mn oxide and Pd coupled to microbial catalysis offer novel potential for advanced water treatment.

Water Research published new progress about Oxidation. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Name: Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Velo-Gala, Inmaculada published the artcileIonic X-ray contrast media degradation in aqueous solution induced by gamma radiation, Application of Diatrizoic Acid, the main research area is ionic x ray contrast media degradation gamma radiation.

The objective of this study was to analyze the effectiveness of gamma irradiation to transform diatrizoate, DTZ, (contrast medium) in aqueous solution determining the role of oxidizing and reducting species on DTZ degradation The mechanisms involved in DTZ degradation have also been studied. Removal of 91.9% of the diatrizoate was achieved at a dose of 1000 Gy at initial concentration of 25 mg/L. The degradation rate depends on the initial concentration The dose constant is independent of the dose rate in the studied range of 3.83-1.06 Gy/min and slightly depends on solution pH in the interval pH 2.0-10.0. Results obtained show that low H2O2 concentrations increase the efficacy of the process, and high concentrations markedly decrease the dose constant The reaction constant of diatrizoate with the hydrogen radical was determined, obtaining a kH[rad] (DTZ) value of (2.2 ± 0.5) × 109 M-1 s-1. DTZ irradiation byproducts have been determined by HPLC-MS and an oxidation/reduction mechanism has been proposed. Three possible degradation pathways based on the major byproducts found at different doses have been proposed. Moreover, the results obtained indicated a further possible compound degradation pathway, which is based on decarboxylation by hydrogen radical or HO· radical with a subsequent attack by hydroxyl radicals against the ketone group.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Gamma ray. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application of Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Liu, Min published the artcileExtraction of Natural Products by Direct Formation of Eutectic Systems, Product Details of C2H6N2O, the main research area is natural product extraction eutectic.

A eutectic system forms when two or more substances reorganize into a superlattice that has a lower m.p. than each of the individual components. Deep eutectic solvents (DESs) are environmentally friendly solvents often used for the dissolution, extraction, and separation of chem. compounds Instead of using DESs for extraction, hydrogen bond acceptors (HBAs) or hydrogen bond donors (HBDs) can be used to form a deep eutectic system (DESys) directly with the target compound for one-step dissolution and extraction The feasibility of direct formation of a DESys for high efficiency extraction was demonstrated with turmeric as the extraction target. The data showed that the target compounds indeed directly interacted with HBAs (and for other compounds, HBDs), which increases process efficiency and reduces the time required for target compounds to compete with another HBD (or HBA) to form hydrogen bonds. In addition, the results showed that the target compounds have different physicochem. properties in DESys and DES, which resulted in different anal. behaviors of the targets. This research may lead to changes in how eutectic systems are used and the development of new applications based on the formation of DESys.

ACS Sustainable Chemistry & Engineering published new progress about Eutectics. 598-50-5 belongs to class isoquinoline, name is 1-Methylurea, and the molecular formula is C2H6N2O, Product Details of C2H6N2O.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Aszyk, Justyna published the artcileComprehensive determination of flavouring additives and nicotine in e-cigarette refill solutions. Part I: Liquid chromatography-tandem mass spectrometry analysis, Quality Control of 21834-92-4, the main research area is electronic cigarette flavoring additive nicotine determination; Electronic cigarettes; Flavouring compounds; Liquid chromatography; Nicotine; Tandem mass spectrometry.

Liquid chromatog.-tandem mass spectrometry with electrospray ionization (HPLC-ESI-MS/MS) methods were developed for the simultaneous determination of 42 flavouring compounds and nicotine in liquids for e-cigarettes. The chromatog. separation was performed using an Ace Ultracore SuperC18 (100 × 2.1 mm, 2.5 μm) column in both acidic and alk. pH conditions to sep. all the compounds A simple “”dilute & shoot”” approach was used for the sample preparation The method validation was performed by evaluating key anal. parameters such as linearity, accuracy, selectivity, precision, limit of detection (LOD) and limit of quantification (LOQ). The calibration curves showed good linearity within the specific ranges for the investigated compounds with correlation coefficients greater than 0.990 in each case. The recovery for all the investigated compounds varied from 89% to 110%. The intra- and inter-day precision were within the acceptable limits (± 15%) at all tested concentrations The applicability of the methods was examined by analyzing 25 liquid samples from e-cigarettes com. available on the Polish market.

Journal of Chromatography A published new progress about E-liquids. 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, Quality Control of 21834-92-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Cemin, Paloma published the artcileChocolates with Brazilian cocoa: Tracking volatile compounds according to consumers’ preference, Computed Properties of 21834-92-4, the main research area is phenethyl acetate phenyl methyl hexenal chocolates cocoa; Acceptance; Aroma; Cocoa liquor; Preference map; Sensory acceptance.

This study aimed to evaluate the volatile compounds of chocolates made of Brazilian cocoas and statistically track them according to the products sensorial profile in order to relate them to consumers’ acceptance by preference map methodol. The intensity of the chocolate, acidity, woody, smoked, green, floral, burned, musty, and cocoa notes from chocolates produced with cocoa from different Brazilian states were analyzed by a trained panel and by 128 consumers. Samples from Cote dIvoire, which is known for its high-quality chocolate, were evaluated for comparison. Solid-phase microextraction headspace sampling/gas chromatog.-mass spectrometry was employed to evaluate the samples volatile compounds One hundred volatile compounds were identified within the samples. The results from the preference maps showed that the maximum preference was found for chocolate made of cocoa from Rondonia, Bahia, and Espirito Santo and Cote dIvoire and organic samples from Para. The ideal sample point was characterized by intense chocolate, floral, and woody notes and mild green and burned notes. The presence of furfural, 3-Me butanal, phenethyl acetate, 2-phenyl-5-methyl-2-hexenal, Me pyrazine, phenethyl acetate, 2-phenyl-5-methyl-2-hexenal, and tetra-Me pyrazine were shown to be important for consumer acceptance in the ideal product, whereas the presence of (Z)-2-heptenal and 2-pentyl furan may increase consumer rejection. 2,3-Me pyrazine, Me pyrazine, and 2,3-butanediol, which are important volatile compounds previously reported in the literature, were statistically tracked to both pos. and neg. sample attributes and must be better explored concerning consumers acceptance of chocolates.

Food Research International published new progress about Chocolate. 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, Computed Properties of 21834-92-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Iio, Keita published the artcileDiscovery of orexin 2 receptor selective and dual orexin receptor agonists based on the tetralin structure: Switching of receptor selectivity by chirality on the tetralin ring, Safety of 4-Methoxyphenylacetic acid, the main research area is orexin 2 receptor agonists chirality structure activity; Agonist; Diarylsulfonamide; OX1R; OX2R; Orexin; Orexin receptor; Tetraline.

A novel series of 1-amino-tetralin derivatives were designed and synthesized based on the putative binding mode of the naphthalene-type orexin receptor agonist 5 and their agonist activities against orexin receptors were evaluated. The introduction of N-methyl-(3-methoxyphenyl)acetamide unit onto the 1-amino-tetralin skeleton remarkably enhanced the potency of the agonist. The asym. synthesis of 6 revealed that (-)-6 having a (S)-1-amino-tetralin skeleton showed a OX2R selective agonist activity (EC50 = 2.69 nM for OX2R, OX1R/OX2R = 461) yet its enantiomer (R)-(+)-6 showed a potent OX1/2R dual agonist activity (EC50 = 13.5 nM for OX1R, 0.579 nM for OX2R, OX1R/OX2R = 23.3). These results suggested that upward orientation of the amide side chain against the tetralin scaffold (S-configuration) would be selective for OX2R activation, and the downward orientation (R-configuration) would be significant for dual agonist activity. To our best knowledge, there have been no reports thus far that the stereochem. of one carbon center on the agonist structure regulates the orexin receptor selectivity. Our results would provide important information for the development of OX1R selective agonists.

Bioorganic & Medicinal Chemistry Letters published new progress about Chirality. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Safety of 4-Methoxyphenylacetic acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Van Nevel, S. published the artcilePalladium nanoparticles produced by fermentatively grown bacteria as catalyst for diatrizoate removal with biogenic hydrogen, Formula: C11H9I3N2O4, the main research area is Citrobacter Clostridium biogenic palladium nanoparticle formation.

This study demonstrated the general applicability of fermentatively grown bacteria (Clostridium butyricum and Citrobacter braakii) to generate catalytic Pd(0) nanoparticles and biol. produced hydrogen as electron donor. A process consisting of microbial hydrogen formation and Pd nanoparticle catalysis without the need for an external electron donor was studied in dehalogenation reactions in batch tests as well as in a membrane bioreactor (MBR) using diatrizoate as model compound The results of using biogenic Pd(0) for diatrizoate dehalogenation in batch experiments and for removal of diatrizoate in an MBR are presented.

Communications in Agricultural and Applied Biological Sciences published new progress about Catalysis. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Formula: C11H9I3N2O4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Hennebel, Tom published the artcileDehalogenation of environmental pollutants in microbial electrolysis cells with biogenic palladium nanoparticles, Application In Synthesis of 117-96-4, the main research area is microbial electrolysis cell palladium trichloroethylene dechlorination catalytic groundwater remediation.

Purpose of work Hydrodehalogenation of persistent pollutants, such as the groundwater contaminants trichloroethylene and diatrizoate, are catalyzed by biogenic Pd nanoparticles. As H2 gas supply for the dehalogenation reactions is still the limiting factor, this study examines in situ H2 production in the cathode of a microbial electrolysis cell. In a biogenic Pd nanoparticle (bio-Pd) free microbial electrolysis cell (MEC), dechlorination of trichloroethylene (TCE) with concomitant chloride and ethane formation was achieved in the cathode compartment at a removal rate of 120 g TCE m-3 total cathode compartment (TCC) day-1, applying -0.8 V with a power source. When the cathode granules were coated with 5 mg bio-Pd g-1 graphite, chloride and ethane formation increased to 151 g TCE m-3 TCC day-1 corresponding with a specific removal rate of 48 mg TCE g-1 Pd day-1. In both cases, formation of unwanted byproducts, such as vinyl chloride, was not significant. When the same setup was applied for transformation of the iodinated contrast medium diatrizoate (diaI3), reduction in a catalyst-free cathode of a MEC resulted in a removal of 48 ± 9% during the first h corresponding to 3 g diaI3 m-3 TCC day-1. Coating the cathodic graphite granules with bio-Pd enhanced the transformation resulting in a 93 ± 4% removal during the first h corresponding to 6 g diaI3 m-3 TCC day-1. These results suggest that MECs can produce H2 in a sustainable way to provide an economical interesting reactant for bio-Pd catalyzed dehalogenation reactions.

Biotechnology Letters published new progress about Catalysis. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application In Synthesis of 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Clemente-Villalba, Jesus published the artcileComparison on sensory profile, volatile composition and consumer’s acceptance for PDO or non-PDO tigernut (Cyperus esculentus L.) milk, Safety of 1,3-Dimethoxybenzene, the main research area is horchata tigernut milk volatile compound penalty analysis.

Cyperus esculentus tubers are the raw material to prepare tigernut milk (horchata), which can be marketed under Protected Designation of Origin “”C hufa de Valencia””. The aim of this study was to characterize com. tigernut milks and compare PDO and non-PDO products. The following aspects were studied: (i) volatile profile, (ii) descriptive sensory profile, (iii) consumer satisfaction degree. The key volatile compounds were limonene, benzaldehyde, linalool and m-methoxyanisole. Principal component anal. indicated a mix of PDO and non-PDO samples in the groups formed. The highest consumer satisfactions were observed for 2 PDO samples. Penalty anal. showed that 80% of non-PDO samples needed improvements, while this percentage drastically decreased to 40% for PDO samples. The online study proved that a lot of people drink horchata, less people know the PDO Chufa de Valencia and even less people consume the protected product consciously. In conclusion, there was not a clear difference among protected and non-protected tigernut milks respect to volatile compounds but there were differences in the degree of consumer preference. So, it is clear that a lack of knowledge regarding the product and its PDO exists and needs attention.

LWT–Food Science and Technology published new progress about Beverages. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem