Tag: M.W=100-150

Massouh, Joe published the artcileRhodium(III)-Catalyzed Aldehyde C-H Activation and Functionalization with Dioxazolones: An Entry to Imide Synthesis, Related Products of isoquinoline, the main research area is methylsulfanylbenzaldehyde dioxazolone rhodium catalyst C H activation amidation; methylsulfanyl benzamide preparation.

A rhodium(III)-based catalytic system was used to develop a C-H bond activation of benzaldehyde derivatives and subsequent functionalization with dioxazolones in order to afford imides. The importance of the nature of the directing group to perform selectively the aldehydic C-H bond activation was highlighted. The scope investigation showed that this transformation was applied to various dioxazolones and many benzaldehyde derivatives as well as an acrolein derivative Derivatization reactions of the imide products demonstrated the synthetic utility of this rhodium-catalyzed aldehydic C-H amidation.

Advanced Synthesis & Catalysis published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Fan, Xiuwei published the artcilePhotocatalytic C-C Bond Activation of Oxime Ester for Acyl Radical Generation and Application, HPLC of Formula: 5961-59-1, the main research area is oxindole cyclobutane preparation photocatalytic carbon bond activation oxime ester.

A unified strategy to generate acyl radical from oxime ester via selective C-C bond activation is reported. Under visible-light irradiation, single-electron transfer from fac-Ir(ppy)3 to related oxime takes place followed by a fast β-fragment of C-C bond to yield aryl and aliphatic acyl radicals, subsequently captured by diverse Michael acceptors. More interestingly, the single-electron transfer enables coupling with energy transfer of the excited fac-Ir(ppy)3 via enone intermediate formed in situ for cyclobutane formation.

Organic Letters published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, HPLC of Formula: 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Kamitanaka, Tohru published the artcile[3+2] Coupling of Quinone Monoacetals with Vinyl Ethers Effected by Tetrabutylammonium Triflate: Regiocontrolled Synthesis of 2-Oxygenated Dihydrobenzofurans, Name: 1,3-Dimethoxybenzene, the main research area is dihydrobenzofuran preparation diastereoselective regioselective; quinone monoacetal vinyl ether coupling tetrabutylammonium triflate catalyst.

The synthesis of 2-oxygenated dihydrobenzofurans I (R = H, Me, t-Bu, OMe, NHAc; R1 = H, Me, t-Bu; R2 = Me, Et; R3 = H, OMe; X = -CH2-, -O-; n = 0, 1), II (R4 = Et, i-Pr; R5 = H, Me) involving the [3+2] coupling of quinone monoacetals III with vinyl ethers IV has been realized by tetrabutylammonium triflate catalysis. The reaction involves a new activation method of the acetal moiety in quinone monoacetals III under acid-free conditions affording the highly oxygenated dihydrobenzofurans I, II. This new activation mode was achieved by using the triflate anion catalyst for stabilization of the highly reactive cationic intermediate.

Organic Letters published new progress about [3+2] Cycloaddition reaction catalysts (regio-, stereoselective). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Name: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Shen, Hui published the artcileSynthesis of 3-substituted 2-oxindoles from secondary α-bromo-propionanilides via palladium-catalyzed intramolecular cyclization, Recommanded Product: 4-Methoxy-N-methylaniline, the main research area is bromo phenylalkanamide palladium catalyst heterocyclization; alkyloxindole preparation.

A palladium-catalyzed intramol. cyclization of α-bromo-propionanilides was developed, delivering a series of 3-substituted 2-oxindoles in high yields. The method features easy to prepare starting materials, broad substrate scope and excellent functional group tolerance. A detailed mechanistic investigation was performed.

Organic & Biomolecular Chemistry published new progress about Aliphatic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Recommanded Product: 4-Methoxy-N-methylaniline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Kwon, Jungmin published the artcileSynthesis of Arenesulfonyl Fluorides via Sulfuryl Fluoride Incorporation from Arynes, Recommanded Product: 4-Methoxy-N-methylaniline, the main research area is arenesulfonyl fluoride preparation; sulfuryl fluoride multicomponent reaction aryne amine; zwitterionic intermediate.

Transition-metal-free multicomponent reactions involving aryne precursors, secondary amines, and sulfuryl fluoride are reported herein. Zwitterionic intermediates formed from the reaction of arynes with amine nucleophiles can capture SO2F2 under mild conditions, offering a novel and practical protocol for the synthesis of 2-dialkyl-, 2-alkylaryl-, or 2-diarylamino-substituted arenesulfonyl fluoride derivatives in good to excellent yields.

Organic Letters published new progress about Alkynes, arynes Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Recommanded Product: 4-Methoxy-N-methylaniline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zeng, Fan-Lin published the artcileVisible light-induced recyclable g-C3N4 catalyzed thiocyanation of C(sp2)-H bonds in sustainable solvents, Formula: C8H11NO, the main research area is arene ammonium thiocyanate carbon nitride catalyst thiocyanation green chem; aryl thiocyanate preparation.

A metal-free photocatalytic strategy for the preparation of thiocyanated heterocycles from inexpensive NH4SCN was developed using carbon nitride (g-C3N4) as a general heterogeneous catalyst in a green solvent under an air atm. and the irradiation of a blue LED. Various thiocyanated heterocycles including indolo[2,1-a]isoquinolin-6(5H)-ones, benzimidazo[2,1-a]isoquinolin-6(5H)-ones, thioflavones, azaspiro[4.5]trienones and imidazo[1,2-a]pyridines were successfully synthesized in good yields (up to 96%). Importantly, this metal-free and external-oxidant-free procedure employed di-Me carbonate as a green medium, avoiding the traditional volatile organic solvents. Moreover, the recyclable g-C3N4 catalyst was used at least 8 times without significant loss of activities.

Green Chemistry published new progress about Alkynyl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Formula: C8H11NO.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Perry, Mitchell R. published the artcileMono, bis, and tris(phosphoramidate) titanium complexes: synthesis, structure, and reactivity investigations, Recommanded Product: 4-Methoxy-N-methylaniline, the main research area is mono bis phosphoramidate titanium preparation crystal mol structure reactivity; hydroamination catalyst mono bis phosphoramidate titanium complex preparation.

A series of variously substituted phosphoramidate titanium complexes bearing dimethylamido ligands are reported. Aryl-substituted ligands impart crystallinity to the systems and allow for the elucidation of the mol. structures via x-ray crystallog. Higher-substituted complexes, including a tris(phosphoramidate)mono(dimethylamido) complex, were isolated and characterized in the solid state, as well as in solution using variable temperature 1H and 31P NMR spectroscopy. The steric bulk possessed by this ligand system, relative to amidate and ureate ligands, has allowed access to a mono(phosphoramidate)tris(dimethylamido) complex. The first solid-state-mol. structure of a mono-ligated 1,3-N,O chelated complex of titanium is reported and compared to the resp. bis- and tris-analogs. These complexes were screened for hydroaminoalkylation activity between secondary amines and terminal alkenes and the intramol. hydroamination of a terminal aminoalkene. Mono(phosphoramidate)tris(dimethylamido) complexes were screened in situ and more active than their resp. bis(N,O)-chelated analogs. The elucidation of these complexes allows for a direct comparison to other N,O-chelates of early transition metals, particularly in their hydroaminoalkylation and hydroamination reactivity.

Dalton Transactions published new progress about Amines, alkenyl Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Recommanded Product: 4-Methoxy-N-methylaniline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Ece, Hamdiye published the artcileSilyl Cyanopalladate-Catalyzed Friedel-Crafts-Type Cyclization Affording 3-Aryloxindole Derivatives, Quality Control of 5961-59-1, the main research area is aryloxindole preparation; diethyl phosphate Friedel Crafts cyclization trimethylsilyl tricyanopalladate complex catalyst.

3-Aryloxindole derivatives were synthesized through a Friedel-Crafts-type cyclization. The reaction was catalyzed by a trimethylsilyl tricyanopalladate complex generated in situ from trimethylsilyl cyanide and Pd(OAc)2. Wide varieties of di-Et phosphates derived from N-arylmandelamides were converted almost quant. into oxindoles. When N,N-dibenzylamide was used instead of an anilide substrate, a benzo-fused δ-lactam was obtained. An oxindole product was subjected to substitution reactions to afford 3,3-diaryloxindoles with two different aryl groups.

Synlett published new progress about Aromatic amides Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Quality Control of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Lin, Weiwei published the artcileSelective N-Methylation of N-Methylaniline with CO2 and H2 over TiO2-Supported PdZn Catalyst, Related Products of isoquinoline, the main research area is methylation methylaniline carbon dioxide titania supported palladium zinc catalyst.

A series of Pd-ZnO/TiO2, Pd/TiO2, and Pd/ZnO catalysts were synthesized and investigated for N-methylation of N-methylaniline (MA) to N,N-dimethylaniline (DMA) with CO2 and H2. A high performance was observed with a Pd-ZnO/TiO2 catalyst, with 99.9% DMA selectivity at 94% MA conversion. By contrast, both Pd/TiO2 and Pd/ZnO were less active and/or selective. The catalytic performance of Pd-ZnO/TiO2 largely depended on reduction temperature and ZnO loading. The rates for MA conversion (rateMA) and DMA production (rateDMA) increased linearly with the amount of PdZn alloy formed. The reaction was likely to take place via intermediates of N-methylformanilide (MFA) and formate. Formate was produced through the reduction of CO2 with H2 as confirmed by in situ diffuse reflectance Fourier transform IR spectroscopy and then added to MA producing MFA, and finally, MFA was subsequently adsorbed and hydrogenated to DMA. All these steps were promoted by the PdZn alloy. The hydrogenation of MFA to DMA was much faster than the N-methylation of MA to MFA; DMA was stable, so the selectivity to DMA was almost 100% over the Pd-ZnO/TiO2 catalyst.

ACS Catalysis published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Kalla, Reddi Mohan Naidu published the artcileFriedel-Crafts benzylation of arenes with benzylic alcohols using sulfonic-acid-functionalized hyper-crosslinked poly(2-naphthol) as a solid acid catalyst, HPLC of Formula: 151-10-0, the main research area is diaryl methane preparation green chem; arene benzylic alc Friedel Crafts benzylation polynaphthol catalyst; sulfonic acid hyper crosslinked polynaphthol preparation.

The porous poly(2-naphthol) was made-up by combining the 2-naphthol, dimethoxymethane as an crosslinker in presence of FeCl3. Furthermore the polymer was functionalized with ClSO3H to get a dense acid catalyst. The reagent is active for benzylation of arenes such as anisole, toluene, p-xylene, mesitylene, ethylbenzene, 1,3-dimethoxybenzene with benzylic alc. irresp. of the nature of substituted arenes. This catalyst is good active compared with other acid catalyst used for Friedel-Crafts benzylation.

Organic Communications published new progress about Alkylarenes Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem