Tag: M.W=150-200

Dabholkar, Vijay V. published the artcileSynthesis and biological evaluation of novel isoindoline 1,3-dione derivatives, Recommanded Product: 4-Methoxyphenylacetic acid, the main research area is benzyl thiadiazolyl isoindoline dione preparation antibacterial antifungal.

A new series of 2-(5-(substituted-benzyl)-1,3,4-thiadiazol-2-yl)-substituted-isoindoline-1,3-dione I [R = H, 2-Me, 4-Cl, 4-OMe, 2,4-di-Cl; R1 = H, 4-Me, 3-NO2] was synthesized by the reaction of 2-amino-5-(substituted)-benzyl-1,3,4-thiadiazole with substituted phthalic anhydride under solvent free conditions and the structures of the compounds were confirmed by IR and NMR. Representative compounds were screened for their anti-microbial activity against Gram-neg. bacteria, E. coli and P. aeruginosa and Gram-pos. bacteria, S. aureus, and C. diphtheriae using disk diffusion method. Some of these compounds were found to exhibit excellent antibacterial activity.

Heterocyclic Letters published new progress about Anhydrides, cyclic Role: RCT (Reactant), RACT (Reactant or Reagent). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Recommanded Product: 4-Methoxyphenylacetic acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wang, Yukang published the artcileElectrophotochemical Decarboxylative Azidation of Aliphatic Carboxylic Acids, HPLC of Formula: 104-01-8, the main research area is alkyl azide preparation green chem electrophotochem; aliphatic carboxylic acid decarboxylative azidation.

An electrophotochem. metal-catalyzed strategy that harnesses the power of light and electricity for radical decarboxylative functionalization of aliphatic carboxylic acids has been reported. This environmentally friendly protocol smoothly converts a diverse array of aliphatic carboxylic acids into the corresponding alkyl azides without using chem. oxidants or azido-group transfer reagents. The visible light energy and elec. energy can be applied in a spatially separated fashion with a modular electro-flow-cell for large-scale synthesis.

ACS Catalysis published new progress about Alkyl azides Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, HPLC of Formula: 104-01-8.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Guan, Renpeng published the artcileDecarboxylative oxygenation of carboxylic acids with O2via a non-heme manganese catalyst, Category: isoquinoline, the main research area is manganese photocatalyst preparation; aryl carboxylic acid manganese photocatalyst oxygenation; arylaldehyde preparation; arylketone preparation.

Decarboxylative oxygenation of carboxylic acids using a non-heme manganese catalyst under blue light irradiation with O2 as the sole oxidant. Featuring mild reaction conditions, the protocol allowed readily available carboxylic acids to be converted into a wide variety of valuable aldehydes, ketones and amides. Mechanistic studies indicated that the decarboxylation and oxygenation involved the formation of active Mn-oxygen species.

Green Chemistry published new progress about Aromatic amides Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Kumar, Devarapalli Ravi published the artcileCopper-Catalyzed Chemoselective 1,4-Reductions: Sequential One-Pot Synthesis of Esters, Formula: C9H10O3, the main research area is cabonyl ester preparation chemoselective; carbonyl compound triethyl phosphonoacetate reduction copper catalyst; indanone preparation chemoselective; triethyl phosphonoacetate carbonyl compound cyclization copper catalyst.

A sequential one-pot Horner-Wadsworth-Emmons reaction followed by [Cu]-catalyzed 1,4-reduction for an efficient preparation of esters (R1)(R2)CHCH2C(O)OC2H5 (R1 = H, Me; R2 = Ph, naphthalen-1-yl, thiophen-2-yl, 2H-1,3-benzodioxol-5-yl, 4-chlorophenyl, etc.; R1R2 = -(CH2)4-, -(CH2)5-, -(CH2)6-) is described. The protocol showed excellent chemoselectivity and broad functional group tolerance. In addition, the strategy was successfully applied for the synthesis of indanones I (R3 = 4-Me, 5-iso-Pr, 7-methoxy, 5-methoxy; R4 = H, Me) by using a single column chromatog. process.

ChemistrySelect published new progress about Aromatic esters Role: SPN (Synthetic Preparation), PREP (Preparation). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Formula: C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Yadykov, Anton V. published the artcileCyclization of Polarized Divinyl Ketones under Aqueous and Ambient Conditions, Recommanded Product: 4-Methoxyphenylacetic acid, the main research area is combretastatin A4 analog preparation Nazarov cyclization polarized divinyl ketone.

An ‘on-water’ protocol has been developed for the synthesis of combretastatin A-4 (CA-4) analogs by cyclization of polarized triaryldivinyl ketones using hydrochloric acid as a promoter in 45-95% yields. The reaction time was reduced by about 30 times due to ultrasonic irradiation at ambient temperature The other advantages of this new method are operational simplicity, easy workup, no column purification, and applicability on a gram-scale. It was shown that the amphiphilicity of the substrate and a low energy barrier of the reaction are a prerequisite for electrophilic and concerted reactions under aqueous and ambient conditions.

Advanced Synthesis & Catalysis published new progress about Combretastatins Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Recommanded Product: 4-Methoxyphenylacetic acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Tekguel, Yeliz published the artcileDetermination of the effect of wheat germ on the mineral and fatty acid composition and aroma compounds of tarhana: A traditional fermented cereal food, Recommanded Product: 5-Methyl-2-phenylhex-2-enal, the main research area is tarhana wheat germ mineral fatty acid aroma compound detection.

In this study, to supply to the trend toward natural and functional foods that do not include synthetic products, the wheat germ which exists as waste in nature was added to tarhana formulation in order to increase the nutritional content of tarhana. Wheat germ supplemented tarhana samples met the recommended dietary allowances of iron. A total of 63 compounds were detected and quantitated in all samples. Terpenes and terpenoids were observed as the dominant compound group. The addition of wheat germ to tarhana dough resulted in an increase in the number of volatile compounds The most abundant odor-active compounds were acetic acid and 2-acetylpyyrole.The mineral (Mg, K, Zn, Mn), fatty acid (undecaenoic, linoleic, gondoic acid, and α-linolenic), oil, acid (propanoic and hexanoic), alc. (linalool, benzyl, phenylethyl), aldehyde ((E)-2-heptenal, nonanal, 5-methyl-2-phenyl-2-hexenal), ketone (3-Octen-2-one), terpene (junipene, citronellol, trans-Carveol) contents of tarhana samples can be increased by addition of the wheat germ. The wheat germ which exists as waste in nature and contains a high amount of essential amino acids, proteins, fatty acids, minerals, dietary fiber, vitamins, etc. Wheat germ can be added to cereal-based food formulation such as tarhana in order to supply to the trend toward natural and functional foods that do not include synthetic products. Tarhana (basically made from yogurt, wheat flour, herbs, tomato, pepper, onion, etc.) which is a traditional fermented dry Turkish soup is rich in vitamins, minerals, and proteins. Wheat germ based-fermented products such as Tarhana may be considered promising new functional foods due to its probiotic effects in order to expand the market due to the increasing trend toward functional foods.

Journal of Food Processing and Preservation published new progress about Acids Role: ANT (Analyte), PRP (Properties), ANST (Analytical Study). 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, Recommanded Product: 5-Methyl-2-phenylhex-2-enal.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Huang, Wenbo published the artcileSynthesis of Multisubstituted Pyrroles from Enolizable Aldehydes and Primary Amines Promoted by Iodine, Name: 5-Methyl-2-phenylhex-2-enal, the main research area is pyrrole preparation enolizable aldehyde amine iodine.

1,2,4-Trisubstituted pyrroles were synthesized from enolizable aliphatic aldehydes and primary aliphatic amines by using iodine as the dual Lewis acid/mild oxidant. In the presence of 3.0 equiv of TBHP, enolizable α,β-unsaturated aldehyde, for example, cocal reacted with aromatic primary amines to form C2-iodized N-arylpyrroles. An acetal-containing pyrrole was successfully prepared from 4-aminobutyraldehyde di-Et acetal, which can be converted easily to 5,6,7,8-tetrahydroindolizine derivatives

Journal of Organic Chemistry published new progress about Aliphatic aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, Name: 5-Methyl-2-phenylhex-2-enal.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Terzic-Jovanovic, Natasa published the artcilePalladium on carbon in PEG-400/cyclohexane catalytic system for efficient decarbonylation of aldehydes and its recoverable and recyclable, Name: 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, the main research area is palladium PEG cyclohexane catalytic system decarbonylation aldehyde green chem.

A simple methodol. for the decarbonylation of aldehydes catalyzed by com. available palladium on carbon in a green two-solvent system is reported. Various aromatic, aliphatic and heteroaromatic aldehydes were transformed to the corresponding decarbonylated products in good yields. Product isolation from the reaction mixture is simple in practice, and the catalyst can be reused three times.

Journal of the Serbian Chemical Society published new progress about Aliphatic aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Name: 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Guo, Rui-Li published the artcileSynthesis of difluoromethylselenoesters from aldehydes via a radical process, Related Products of isoquinoline, the main research area is difluoromethylselenoester preparation; aldehyde benzyl difluoromethyl selane radical difluoromethylselenolation azobisisobutyronitrile catalyst.

Difluoromethylselenoester compounds RC(O)SeCF2H (R = 4-methylphenyl, furan-2-yl, 1-naphthyl, etc.), another important kind of organoselenium compounds, are reported herein for the first time. They can be efficiently synthesized from aldehydes RCHO and BnSeCF2H. The synthetic method features mild reaction conditions, broad substrate scope, good tolerance of functional groups, and importantly, no metal is involved in the reaction.

Chemical Communications (Cambridge, United Kingdom) published new progress about Aliphatic aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Dogga, Bhushanarao published the artcilePalladium-catalyzed reductive carbonylation of (hetero)aryl halides and triflates using cobalt carbonyl as CO source, Product Details of C9H10O3, the main research area is arylcarboxaldehyde preparation aryl halide triflate reductive carbonylation cobalt carbonyl; heteroaryl carboxaldehyde preparation.

An efficient protocol for the reductive carbonylation of (hetero) aryl halides and triflates under CO gas-free conditions using Pd/Co2(CO)8 and triethylsilane has been developed. The mild reaction conditions, enhanced chemoselectivity and, easy access to heterocyclic and vinyl carboxaldehydes highlights its importance in organic synthesis.

European Journal of Organic Chemistry published new progress about Aryl aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Product Details of C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem