Day: December 1, 2022

Xiong, Jie published the artcileA highly fluorescent lanthanide metal-organic framework as dual-mode visual sensor for berberine hydrochloride and tetracycline, Synthetic Route of 1455-77-2, the main research area is fluorescent lanthanide metal organic framework sensor berberine hydrochloride tetracycline; Berberine hydrochloride; Dual-mode sensor; Metal-organic framework; Tetracycline; Visual detection.

A microscale highly fluorescent Eu metal-organic framework (Eu-MOF) was synthesized with terephthalic acid and 1H-1,2,4-triazole-3,5-diamine by one-pot hydrothermal method. And it was characterized by scanning electron microscope, FTIR spectroscopy, powder x-ray diffraction, fluorescence spectroscopy, TGA, and energy dispersive x-ray mapping. The prepared Eu-MOF has high quantum yield of 30.99%, excellent water dispersibility, good fluorescence stability, and favorable thermal stability. Based on the distinctly different fluorescence responses of different emission, the prepared Eu-MOF was used as dual-mode visual sensor for the sensitive detection of berberine hydrochloride and tetracycline. The limits of detection are 78 nM and 17 nM, resp. The sensing mechanism is also discussed. Moreover, a filter paper sensor has been designed for sensing tetracycline with a notable fluorescence color change from blue to red. The prepared Eu-MOF is promising to be developed as a multi-mode luminescent sensor for visual detection in biochem. anal.

Analytical and Bioanalytical Chemistry published new progress about Filter paper. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Synthetic Route of 1455-77-2.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xiong, Jie published the artcileA highly fluorescent lanthanide metal-organic framework as dual-mode visual sensor for berberine hydrochloride and tetracycline, Product Details of C2H5N5, the main research area is fluorescent lanthanide metal organic framework sensor berberine hydrochloride tetracycline; Berberine hydrochloride; Dual-mode sensor; Metal-organic framework; Tetracycline; Visual detection.

A microscale highly fluorescent Eu metal-organic framework (Eu-MOF) was synthesized with terephthalic acid and 1H-1,2,4-triazole-3,5-diamine by one-pot hydrothermal method. And it was characterized by scanning electron microscope, FTIR spectroscopy, powder x-ray diffraction, fluorescence spectroscopy, TGA, and energy dispersive x-ray mapping. The prepared Eu-MOF has high quantum yield of 30.99%, excellent water dispersibility, good fluorescence stability, and favorable thermal stability. Based on the distinctly different fluorescence responses of different emission, the prepared Eu-MOF was used as dual-mode visual sensor for the sensitive detection of berberine hydrochloride and tetracycline. The limits of detection are 78 nM and 17 nM, resp. The sensing mechanism is also discussed. Moreover, a filter paper sensor has been designed for sensing tetracycline with a notable fluorescence color change from blue to red. The prepared Eu-MOF is promising to be developed as a multi-mode luminescent sensor for visual detection in biochem. anal.

Analytical and Bioanalytical Chemistry published new progress about Filter paper. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Product Details of C2H5N5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Yang, Ning Ning published the artcileTwo new compounds from mycelial fermentation products with nematicidal activity of Marasmius berteroi, Computed Properties of 104-01-8, the main research area is Marasmius Panagrellus mycelium fermentation nematicidal.

Chem. investigation on the cultures of the fungus Marasmius berteroi, resulted in the isolation of 10 compounds including 2 new ones named (S)-3,7-dihydroxy-1-indanone (1) and (S)-3-hydroxy-4-methoxy-3-Me isobenzofuran-1(3H)-one (2). Their structures were determined based on NMR, HRESIMS and ECD spectra anal. Compounds 5-6, 10 revealed moderate inhibitory activity against the nematode Panagrellus redivivus with mortality ratio of 95 %, 85 %, and 75 % at 2.5 mg/mL, resp.

Phytochemistry Letters published new progress about Fermentation. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Computed Properties of 104-01-8.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zhang, Hongyang published the artcileGC-MS profiling of volatile components in different fermentation products of Cordyceps sinensis mycelia, Safety of 5-Methyl-2-phenylhex-2-enal, the main research area is fermentation Cordyceps sinensis; Cordyceps sinensis mycelia; Simultaneous distillation-extraction; fermentation products; gas chromatography-mass spectrometry; partial least squares-discriminant analysis; quality evaluation; volatile profiling.

The fermentation products of Cordyceps sinensis (C. sinensis) mycelia are sustainable substitutes for natural C. sinensis. However, the volatile compositions of the com. products are still unclear. In this paper, we have developed a simultaneous distillation-extraction (SDE) and gas chromatog.-mass spectrometry (GC-MS) method for the profiling of volatile components in five fermentation products. A total of 64, 39, 56, 52, and 44 components were identified in the essential oils of Jinshuibao capsule (JSBC), Bailing capsule (BLC), Zhiling capsule (ZLC), Ningxinbao capsule (NXBC), and Xinganbao capsule (XGBC), resp. 5,6-Dihydro-6-pentyl-2H-pyran-2-one (massoia lactone) was first discovered as the dominant component in JSBC volatiles. Fatty acids including palmitic acid (C16:0) and linoleic acid (C18:2) were also found to be major volatile compositions of the fermentation products. The multivariate partial least squares-discriminant anal. (PLS-DA) showed a clear discrimination among the different com. products as well as the counterfeits. This study may provide further chem. evidences for the quality evaluation of the fermentation products of C. sinensis mycelia.

Molecules published new progress about Fermentation. 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, Safety of 5-Methyl-2-phenylhex-2-enal.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xu, Niansheng published the artcileHelical polycycle molecular semiconductor for durable and efficient perovskite solar cells, Application of 4-Methoxy-N-methylaniline, the main research area is polycycle mol semiconductor perovskite solar cell perovskite layer.

Despite the efficiency comparable to crystalline silicon photovoltaics, it is still a severe concern on the long-term stability under the stress of heat, light, and bias potential for perovskite solar cell (PSC). Here, we report a triple aza[6]helicene-based mol. semiconductor (TBTA[6]H) characteristic of a fully fused conjugated backbone. TBTA[6]H presents superior solubility and glass-transition temperature (Tg). An air-doped composite of TBTA[6]H with a high elec. conductivity of 353μS cm-1 is still featured by a Tg of 112°C, enabling the fabrication of 22% efficiency, 85°C durable PSCs. The TBTA[6]H composite not only exhibits an excellent morphol. stability at 85°C in PSCs, but also remarkably attenuates the thermal degradation of photoactive perovskite layer. The cell with TBTA[6]H also displays an excellent operation stability under the continuous full sunlight soaking at 55°C.

ACS Materials Letters published new progress about Doping (air). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Application of 4-Methoxy-N-methylaniline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Dong, Huiyu published the artcileOxidation of iopamidol with ferrate (Fe(VI)): Kinetics and formation of toxic iodinated disinfection by-products, COA of Formula: C11H9I3N2O4, the main research area is ferrate iopamidol oxidation toxic iodinated disinfection byproduct kinetics formation; Ferrate; Iodinated disinfection by-products; Iopamidol; Kinetics.

Presence of iodinated X-ray contrast media (ICMs) in source water is of high concern, because of their potential to form highly toxic iodinated disinfection byproducts (I-DBPs). This study investigated kinetics, mechanisms and products for oxidation of one ICMs, iopamidol (IPM) by ferrate (Fe(VI)). The obtained apparent second-order rate constants for oxidation of IPM by Fe(VI) ranged from 0.7 M-1 s-1 to 74.6 M-1 s-1 at pH 6.0-10.0, which were highly dependent on pH. It was found that the oxidation of IPM by Fe(VI) led to the formation of highly toxic I-DBPs. Iodoform (IF), iodoacetic acid and triiodoacetic acid formations were observed during the oxidation and IF dominated the formed I-DBPs. The formation of I-DBPs was also governed by pH and the maximum formation of I-DBPs occurred at pH 9.0. Transformation pathways of IPM by Fe(VI) oxidation were speculated to proceed through deiodination, amide hydrolysis and oxidation of amine reactions. The deiodination reaction during the oxidation of IPM by Fe(VI) contributed to the formation of I-DBPs. The formation of I-DBPs during the oxidation of IPM by Fe(VI) was significantly higher than those of iohexol, diatrizoate and iopromide, which was consistent with the lowest MO energy gap of IPM. Although Fe(VI) is considered as a green oxidant, the formation of highly toxic I-DBPs during the oxidation of IPM should receive great attention.

Water Research published new progress about Deiodination. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, COA of Formula: C11H9I3N2O4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xu, Haodan published the artcileThiourea Dioxide Coupled with Trace Cu(II): An Effective Process for the Reductive Degradation of Diatrizoate, Application In Synthesis of 117-96-4, the main research area is thiourea dioxide copper reductive degradation diatrizoate wastewater; Cu(I) complexes; deiodination; diatrizoate; hospital wastewater; reduction reaction; refractory X-ray contrast media compounds; thiourea dioxide; trace concentrations of copper.

Diatrizoate, a refractory ionic iodinated X-ray contrast media (ICM) compound, cannot be efficiently degraded in a complex wastewater matrix even by advanced oxidation processes. We report in this research that a homogeneous process, thiourea dioxide (TDO) coupled with trace Cu(II) (several micromoles, ubiquitous in some wastewater), is effective for reductive deiodination and degradation of diatrizoate at neutral pH values. Specifically, the molar ratio of iodide released to TDO consumed reached 2 under ideal exptl. conditions. TDO eventually decomposed into urea and sulfite/sulfate. Based on the results of diatrizoate degradation, TDO decomposition, and Cu(I) generation and consumption during the TDO-Cu(II) reaction, we confirmed that Cu(I) is responsible for diatrizoate degradation However, free Cu(I) alone did not work. It was proposed that Cu(I) complexes are actual reactive species toward diatrizoate. Inorganic anions and effluent organic matter neg. influence diatrizoate degradation, but by increasing the TDO dosage, as well as extending the reaction time, its degradation efficiency can still be guaranteed for real hospital wastewater. This reduction reaction could be potentially useful for in situ deiodination and degradation of diatrizoate in hospital wastewater before discharge into municipal sewage networks.

Environmental Science & Technology published new progress about Deiodination. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Application In Synthesis of 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Yan, Mingquan published the artcileElectrochemical reductive dehalogenation of iodine-containing contrast agent pharmaceuticals: Examination of reactions of diatrizoate and iopamidol using the method of rotating ring-disc electrode (RRDE), Recommanded Product: Diatrizoic Acid, the main research area is diatrizoate iopamidol electrochem reductive dehalogenation water purification; Diatrizoate; Electrochemical; Iodine; Iopamidol; NOM; Rotating ring-disc electrode.

This study examined the electrochem. (EC) reduction of iodinated contrast media (ICM) exemplified by iopamidol and diatrizoate. The method of rotating ring-disc electrode (RRDE) was used to elucidate rates and mechanisms of the EC reactions of the selected ICMs. Experiments were carried at varying hydrodynamic conditions, concentrations of iopamidol, diatrizoate, natural organic matter (NOM) and model compounds (resorcinol, catechol, guaiacol) which were used to examine interactions between products of the EC reduction of ICMs and halogenation-active species. The data showed that iopamidol and diatrizoate were EC-reduced at potentials < -0.45 V vs. s.c.e. In the range of potentials -0.65 to -0.85 V their reduction was mass transfer-controlled. The presence of NOM and model compounds did not affect the EC reduction of iopamidol and diatrizoate but active iodine species formed as a result of the EC-induced transformations of these ICMs reacted readily with NOM and model compounds These data provide more insight into the nature of generation of iodine-containing byproducts in the case of reductive degradation of ICMs. Water Research published new progress about Deiodination. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Recommanded Product: Diatrizoic Acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zhou, Lei published the artcileInvestigations of diatrizoate degradation by photo-activated persulfate, Related Products of isoquinoline, the main research area is diatrizoate UV photodegradation persulfate hydroxyl.

The widespread occurrence of iodinated X-ray contrast media (ICMs) in aquatic systems poses potential risks to ecol. system and human health. The present study investigated the degradation kinetics and mechanisms of a typical ICMs, diatrizoate (DTZ), by using simulated sunlight (from a solar simulator Suntest CPS+) activated persulfate (PS) oxidation process. The influence of key kinetic factors, such as PS concentrations, pH, dissolved organic matter (DOM), bicarbonate and chloride ions was evaluated. The reaction pathways and mechanisms were proposed based on photoproducts identification using HPLC-MS. UV/PS was found to be more efficient than UV/H2O2. Sulfate radicals (SO·-4) was the dominant reactive species in the oxidation process, and the second-order rate constant of sulfate radical with DTZ was calculated as 1.90 × 109 M-1s-1 based on laser flash photolysis (LFP) experiments The results indicated that increasing initial PS concentration favored the decomposition of DTZ; whereas, degradation of DTZ was not affected by pH change ranging from 4.5 to 8.5. DOM inhibited DTZ removal rate, while, bicarbonate enhanced it, and chloride ions induced a neg. effect above 500 mM. Major oxidation pathways including deiodination-hydroxylation, decarboxylation- hydroxylation and side chain cleavage were proposed, and detailed underlying mechanisms were also discussed. We suggest a direct photodegradation of primary intermediates generated by SO·-4 attack. These findings demonstrate that halogenated pollutants can readily react with SO·-4 to form light-absorbing intermediates (ranging from 350 to 500 nm). Thus, this activation method could be a promising approach in the removal of ICMs.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Deiodination. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Andreucci, Michele published the artcileReversal of radiocontrast medium toxicity in human renal proximal tubular cells by white grape juice extract, Formula: C11H9I3N2O4, the main research area is radiocontrast medium nephrotoxicity radiotoxicity Vitis juice extract radioprotectant; Cell injury; Kinase; Renal cell; Signaling; Vitis spp..

Radiocontrast media (RCM)-induced nephrotoxicity (CIN) is a major clin. problem accounting for 12% of all hospital-acquired cases of acute kidney injury. The pathophysiol. of CIN is not well understood, but direct toxic effects on renal cells have been postulated as contributing to CIN. We have investigated the effect of a white grape (Vitis vinifera) juice extract (WGJe) on human renal proximal tubular (HK-2) cells treated with the radiocontrast medium (RCM) sodium diatrizoate. WGJe caused an increase in phosphorylation of the prosurvival kinases Akt and ERK1/2 in HK-2 cells. Treatment of HK-2 cells with 75 mg I/mL sodium diatrizoate for 2.5 h and then further incubation (for 27.5 h) after removal of the RCM caused a drastic decrease in cell viability. However, pre-treatment with WGJe, prior to incubation with diatrizoate, dramatically improved cell viability. Anal. of key signaling mols. by Western blotting showed that diatrizoate caused a drastic decrease in phosphorylation of Akt (Ser473), FOXO1 (Thr24) and FOXO3a (Thr32) during the initial 2.5 h incubation period, and WGJe pre-treatment caused a reversal of these effects. Further anal. by Western blotting of samples from HK-2 cells cultured for longer periods of time (for up to 27.5 h after an initial 2.5 h exposure to diatrizoate with or without WGJe pre-treatment) showed that WGJe pre-treatment caused a neg. effect on phosphorylation of p38, NF-κB (Ser276) and pERK1/2 while having a pos. effect on the phosphorylation of Akt, FOXO1/FOXO3a and maintained levels of Pim-1 kinase. WGJe may alleviate RCM toxicity through modulation of signaling mols. that are known to be involved in cell death and cell survival and its possible beneficial effects should be further investigated.

Chemico-Biological Interactions published new progress about Cytotoxicity. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, Formula: C11H9I3N2O4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem