Month: December 2022

Nabipour, Hafezeh published the artcileFacile synthesis of a novel zinc-triazole complex for simultaneous improvement in fire safety and mechanical properties of epoxy resins, Application of 3,5-Diamino-1,2,4-triazole, the main research area is epoxy resin zinc triazole complex mech property flame retardancy.

A novel zinc-triazole complex (ZTC) was synthesized by a co-precipitation method. The addition of 4 wt% of ZTC showed slight change in the thermal stability of the epoxy resin (EP) matrix, whereas the inclusion of 4 wt% of 3,5-diamino-1,2,4-triazole deteriorated the thermal stability. The glass transition temperature (Tg) of EP/ZTC-4% was dramatically enhanced to 162° from 150° for the unmodified epoxy, which could be ascribed to the increased crosslinking d. and the structural rigidity of ZTC. The flame-retardant property of EP/ZTC-4% was greatly improved, achieving UL-94 V-0 classification and a LOI value of 29.0%. The peak heat release rate, total heat release and smoke production rate of EP/ZTC-4% were dramatically declined by 72.9%, 86.0% and 73.8%, resp., compared to the unmodified EP. Such desirable features including high fire retardant efficiency and proper smoke suppression make zinc-triazole complex a promising candidate for high fire safety polymers.

Composites, Part A: Applied Science and Manufacturing published new progress about Chars. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Application of 3,5-Diamino-1,2,4-triazole.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Karabagias, Ioannis K. published the artcileBotanical discrimination of Greek unifloral honeys with physico-chemical and chemometric analyses, SDS of cas: 21834-92-4, the main research area is honey classification botanical origin volatile compound chemometrics; Chemical markers; Chemometrics; Classification; Multi element analysis; Unifloral honeys.

The aim of the present study was to investigate the possibility of characterization and classification of Greek unifloral honeys (pine, thyme, fir and orange blossom) according to botanical origin using volatile compounds, conventional physico-chem. parameters and chemometric analyses (MANOVA and Linear Discriminant Anal.). For this purpose, 119 honey samples were collected during the harvesting period 2011 from 14 different regions in Greece known to produce unifloral honey of good quality. Physico-chem. anal. included the identification and semi quantification of fifty five volatile compounds performed by Headspace Solid Phase Microextraction coupled to gas chromatog./mass spectroscopy and the determination of conventional quality parameters such as pH, free, lactonic, total acidity, elec. conductivity, moisture, ash, lactonic/free acidity ratio and color parameters L*, a*, b*. Results showed that using 40 diverse variables (30 volatile compounds of different classes and 10 physico-chem. parameters) the honey samples were satisfactorily classified according to botanical origin using volatile compounds (84.0% correct prediction), physicochem. parameters (97.5% correct prediction), and the combination of both (95.8% correct prediction) indicating that multi- element anal. comprises a powerful tool for honey discrimination purposes.

Food Chemistry published new progress about Abies. 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, SDS of cas: 21834-92-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xie, Xiaoyu published the artcileIn-depth profiling of carboxyl compounds in Chinese Baijiu based on chemical derivatization and ultrahigh-performance liquid chromatography coupled to high-resolution mass spectrometry, Product Details of C9H10O3, the main research area is Chinese Baijiu carboxyl compound chem derivatization UHPLC HRMS; Carboxyl compounds; Chemical derivatization; Chinese Baijiu; High-coverage analysis; High-resolution mass spectrometry.

Carboxyl compounds have a significant influence on the flavor of Chinese Baijiu. However, because of the structural diversity and low concentration, the deep profiling of carboxyl compounds in Chinese Baijiu is still challenging. In this work, a systematic method for comprehensive anal. of carboxyl compounds in Chinese Baijiu was established. After derivatized under optimized conditions, 197 p-dimethylaminophenacyl bromide-derived carboxylic compounds were annotated by multidimensional information including accurate mass, predicted tR, in-silico MS/MS, and diagnostic ions for the first time. In addition, 48 of the 197 carboxyl compounds were pos. identified, and three of them were newly identified in Chinese Baijiu. Moreover, we found the number and the concentration of carboxyl compounds in sauce-flavor Baijiu were more abundant than in strong-flavor Baijiu. This work provides a novel method for the anal. of carboxyl compounds in Baijiu and other complex samples.

Food Chemistry: X published new progress about Baijiu. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Product Details of C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Radjenovic, Jelena published the artcileRemoval of the X-ray contrast media diatrizoate by electrochemical reduction and oxidation, HPLC of Formula: 117-96-4, the main research area is xray contrast media diatrizoate electrochem reduction oxidation.

Due to their resistance to biol. wastewater treatment, iodinated X-ray contrast media (ICM) have been detected in municipal wastewater effluents at relatively high concentrations (i.e., up to 100 μg L-1), with hospitals serving as their main source. To provide a new approach for reducing the concentrations of ICMs in wastewater, electrochem. reduction at three-dimensional graphite felt and graphite felt doped with palladium nanoparticles was examined as a means for deiodination of the common ICM diatrizoate. The presence of palladium nanoparticles significantly enhanced the removal of diatrizoate and enabled its complete deiodination to 3,5-diacetamidobenzoic acid. When the system was employed in the treatment of hospital wastewater, diatrizoate was reduced, but the extent of electrochem. reduction decreased as a result of competing reactions with solutes in the matrix. Following electrochem. reduction of diatrizoate to 3,5-diacetamidobenzoic acid, electrochem. oxidation with boron-doped diamond (BDD) anodes was employed. 3,5-Diacetamidobenzoic acid disappeared from solution at a rate that was similar to that of diatrizoate, but it was more readily mineralized than the parent compound When electrochem. reduction and oxidation were coupled in a three-compartment reactor operated in a continuous mode, complete deiodination of diatrizoate was achieved at an applied cathode potential of -1.7 V vs SHE, with the released iodide ions electrodialyzed in a central compartment with 80% efficiency. The resulting BDD anode potential (i.e., +3.4-3.5 V vs SHE) enabled efficient oxidation of the products of the reductive step. The presence of other anions (e.g., chloride) was likely responsible for a decrease in I- separation efficiency when hospital wastewater was treated. Reductive deiodination combined with oxidative degradation provides benefits over oxidative treatment methods because it does not produce stable iodinated intermediates. Nevertheless, the process must be further optimized for the conditions encountered in hospital wastewater to improve the separation efficiency of halide ions prior to the electrooxidation step.

Environmental Science & Technology published new progress about Anodes. 117-96-4 belongs to class isoquinoline, name is Diatrizoic Acid, and the molecular formula is C11H9I3N2O4, HPLC of Formula: 117-96-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Morris, David T. J. published the artcileA molecular communication channel consisting of a single reversible chain of hydrogen bonds in a conformationally flexible oligomer, Application In Synthesis of 5961-59-1, the main research area is mol communication channel hydrogen bond oligomer single reversible chain; NMR; binding; communication; conformation; dynamic foldamer; hydrogen bonding; information theory; oligomer; stimulus responsive; urea.

Communication of information through the global switching of conformation in synthetic mols. has hitherto entailed the inversion of chirality. Here, we report a class of oligomer through which information may be communicated through a global reversal of polarity. Ethylene-bridged oligoureas are constitutionally sym., conformationally flexible mols. organized by a single chain of hydrogen bonds running the full length of the oligomer. NMR reveals that this hydrogen-bonded chain may undergo a coherent reversal of directionality. The directional uniformity of the hydrogen-bond chain allows it to act as a channel for the spatial communication of information on a mol. scale. A binding site at the terminus of an oligomer detects local information about changes in pH or anion concentration and transmits that information-in the form of a directionality switch in the hydrogen-bond chain-to a remote polarity-sensitive fluorophore. This propagation of polarity-encoded information provides a new mechanism for mol. communication.

Chem published new progress about Anions. 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Application In Synthesis of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Glorian, Julien published the artcileHeat of Formation of Triazole-Based Salts: Prediction and Experimental Validation, Formula: C2H5N5, the main research area is triazole salt heat formation physicochem property.

This work contributes to the growing interest in predictions linked with energetic salts. A reliable method to accurately compute the heat of formation of triazole-based salts was investigated. Calculations were based on Born-Haber energy cycles: gas-phase enthalpy of ions and lattice enthalpy were calculated sep. Ten triazole-based salts were synthesized and fully characterized. Their heat of combustion was measured by bomb calorimeter. Gas-phase heat of formation of cations and anions were computed at four different levels of theory: B3LYP 6-31G(d,p), CBS-4M, CBS-QB3, and G4. Ionic volumes were calculated at the B3LYP 6-31G(d,p) level with and without corrections. Lattice enthalpy estimations, based on calculated ionic volumes, were performed with the help of Jenkins and Gutowski methods. Combinations of the obtained results (gas-phase enthalpy of ions and lattice enthalpy) were used in the Born-Haber approach to predict solid phase enthalpy of formation of studied energetic salts. Direct comparison with exptl. measurements enabled the identification of the most reliable path for energetic salt standard enthalpy of formation prediction.

Propellants, Explosives, Pyrotechnics published new progress about Anions. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Formula: C2H5N5.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Glorian, Julien published the artcileHeat of Formation of Triazole-Based Salts: Prediction and Experimental Validation, Category: isoquinoline, the main research area is triazole salt heat formation physicochem property.

This work contributes to the growing interest in predictions linked with energetic salts. A reliable method to accurately compute the heat of formation of triazole-based salts was investigated. Calculations were based on Born-Haber energy cycles: gas-phase enthalpy of ions and lattice enthalpy were calculated sep. Ten triazole-based salts were synthesized and fully characterized. Their heat of combustion was measured by bomb calorimeter. Gas-phase heat of formation of cations and anions were computed at four different levels of theory: B3LYP 6-31G(d,p), CBS-4M, CBS-QB3, and G4. Ionic volumes were calculated at the B3LYP 6-31G(d,p) level with and without corrections. Lattice enthalpy estimations, based on calculated ionic volumes, were performed with the help of Jenkins and Gutowski methods. Combinations of the obtained results (gas-phase enthalpy of ions and lattice enthalpy) were used in the Born-Haber approach to predict solid phase enthalpy of formation of studied energetic salts. Direct comparison with exptl. measurements enabled the identification of the most reliable path for energetic salt standard enthalpy of formation prediction.

Propellants, Explosives, Pyrotechnics published new progress about Anions. 1455-77-2 belongs to class isoquinoline, name is 3,5-Diamino-1,2,4-triazole, and the molecular formula is C2H5N5, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Lori, G. published the artcileHoney extracts inhibit PTP1B, upregulate insulin receptor expression, and enhance glucose uptake in human HepG2 cells, Synthetic Route of 104-01-8, the main research area is heaptocellular carcinoma glycemic honey PTP1B insulin receptor glucose; Insulin signaling; Phenolic compounds; Protein-tyrosine phosphatase 1B; Tuscany honey; Type 2 diabetes.

Honey is a food known for its medical properties. In this work, we have studied the impact of different types of honey on insulin signalling pathway. We found that honey extracts inhibit the enzyme PTP1B, one of the main neg. regulators of insulin receptor signalling. HPLC-MS anal. allowed us to confirm the presence of several natural PTP1B inhibitors in the honey extracts analyzed. Statistical anal. methods show a correlation between specific 1H-NMR resonance frequencies/HPLC peaks and the inhibitory power of the samples. This finding will allow the prediction of the biol. properties of honey samples applying relative simple anal. methods. Finally, we demonstrated that the treatment of HepG2 cells with honey extracts enhances the expression of insulin receptor, and stimulates glucose uptake. For the first time, our results demonstrate that bioactive components of honey could improve glycemic control by both inhibiting PTP1B and stimulating the expression of insulin receptor in liver cells.

Biomedicine & Pharmacotherapy published new progress about Acacia. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Synthetic Route of 104-01-8.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Margaoan, Rodica published the artcileMonofloral Honeys as a Potential Source of Natural Antioxidants, Minerals and Medicine, Recommanded Product: 4-Methoxyphenylacetic acid, the main research area is review monofloral honey natural antioxidant mineral medicine; anticancer; antioxidant activity; monofloral honey; phenolic compounds; physicochemical properties.

Background: vegetative diversity is based on different climate and geog. origins. In terms of beekeeping, herbal diversity is strongly correlated to the production of a wide variety of honey. Therefore, based on the existing plant diversity in each country, multiple honey varieties are produced with different health characteristics. While beekeeping potential and consumption preferences are reflected in productsâ€?variety, this leads to an increase in the region′s economy and extensive export. In the last years, monofloral honey has gained interest from consumers and especially in the medicinal field due to the presence of phytochems. which are directly linked to health benefits, wound healing, antioxidant, anticancer and anti-inflammatory activities. Scope and approach: this review aims to highlight the physicochem. properties, mineral profiles and antioxidant activities of selected monofloral honeys based on their botanical and geog. origin. Moreover, this review focuses on the intercorrelation between monofloral honey′s antioxidant compounds and in vitro and in vivo activities, focusing on the apoptosis and cell proliferation inhibition in various cell lines, with a final usage of honey as a potential therapeutic product in the fight towards reducing tumor growth. Key findings and conclusions: multiple studies have demonstrated that monofloral honeys have different physicochem. structures and bioactive compounds Useful chem. markers to distinguish between monofloral honeys were evidenced, such as: 2-methoxybenzoic acid and trimethoxybenzoic acid are distinctive to Manuka honey while 4-methoxyphenylacetic acid is characteristic to Kanuka honey. Furthermore, resveratrol, epigallocatechin and pinostrobin are markers distinct to Sage honey, whereas carvacrol and thymol are found in Ziziphus honey. Due to their polyphenolic profile, monofloral honeys have significant antioxidant activity, as well as antidiabetic, antimicrobial and anticancer activities. It was demonstrated that Pine honey decreased the MDA and TBARS levels in liver, kidney, heart and brain tissues, whereas Malicia honey reduced the low-d. lipoprotein level. Consumption of Clover, Acacia and Gelam honeys reduced the weight and adiposity, as well as trygliceride levels. Furthermore, the antiproliferative effect of chrysin, a natural flavone in Acacia honey, was demonstrated in human (A375) and murine (B16-F1) melanoma cell lines, whereas caffeic acid, a phenolic compound found in Kelulut honey, proves to be significant candidate in the chemoprevention of colon cancer. Based on these features, the use of hiney in the medicinal field (apitherapy), and the widespread usage of natural product consumption, is gaining interest by each year.

Antioxidants published new progress about Acacia. 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, Recommanded Product: 4-Methoxyphenylacetic acid.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Dymerski, Tomasz published the artcileBotanical and geographical origin characterization of polish honeys by headspace SPME-GC×GC-TOFMS, Quality Control of 21834-92-4, the main research area is VOC geog origin honey microextraction chromatog mass spectrometry Poland.

Volatile organic compounds (VOCs) composition of Polish honeys obtained from various geog. regions was studied. Headspace solid phase microextraction (HS-SPME) using Divinylbenzene/Carboxen/Polydimethylsiloxane-coated fibers was used in combination with comprehensive two-dimensional gas chromatog.-time-of-flight mass spectrometry (GC×GC-TOFMS) because of the complexity of the samples. Acacia, linden, rapeseed, buckwheat and honeydew honeys were studied in this project. A total of 329 compounds were identified during the investigations. Pos. identification of 82 compounds was achieved using anal. standards, while tentative identification of 247 compounds was based on comparison of deconvoluted mass spectra and linear temperature programmed retention indexes (LTPRI) with NIST 2005 library and literature values, resp. Many VOCs identified in Polish honey samples were commonly present in honeys from other geog. regions of Europe (e.g. Italy, Corsica). They included certain acyclic and cyclic alkanes, acyclic and cyclic alkenes, aromatic hydrocarbons, oxygenated aromatic compounds, alcs., aldehydes, ketones, esters, ethers, nitriles, organic sulfides, phenolic compounds and terpenes. GC×GC-TOFMS profiles for the same types of honey samples were remarkably similar. Eight botanic discriminants were selected among all compounds Their identity was confirmed by comparison with authentic standards Furthermore, possible geog. discriminants for Polish honeys were identified, including 19 for acacia, 3 for linden, 3 for rapeseed and buckwheat and 6 for honeydew honeys.

Current Organic Chemistry published new progress about Acacia. 21834-92-4 belongs to class isoquinoline, name is 5-Methyl-2-phenylhex-2-enal, and the molecular formula is C13H16O, Quality Control of 21834-92-4.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem