Category: 151-10-0

Xu, Haiyan published the artcileDABCO as a practical catalyst for aromatic halogenation with N-halosuccinimides, Related Products of isoquinoline, the main research area is aromatic compound halosuccinimide DABCO catalyst halogenation; aryl halide regioselective preparation.

A simple and practical synthetic approach for synthesis of aromatic halides was developed. Simple Lewis base, DABCO, was used as the catalyst. This arene halogenation process proceeded conveniently and efficiently at ambient conditions, providing the desired products in good to excellent yields and selectivity.

RSC Advances published new progress about Aryl halides Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Takenaga, Naoko published the artcileNucleophilic arylation of halopurines facilitated by Bronsted acid in fluoroalcohol, Related Products of isoquinoline, the main research area is aryl substituted purine preparation; halopurine aromatic compound nucleophilic arylation triflic acid facilitated; aromatic substitution; arylation; fluoroalcohol; nucleobase; purine.

Various aryl-substituted purine derivatives I [Ar = 4-HO-1-naphthyl, 4-MeO-1-naphthyl, 1-Me-indol-3-yl, 1-Ph-indol-3-yl; R = H, Bn] II [Ar1 = 2,4-di-OH, 4-HO-1-naphthyl, 1H-indol-3-yl, etc.] were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalc. This metal-free method was complementary to conventional coupling reactions using metal catalysts and reagents for the syntheses of aryl-substituted purine analogs.

Molecules published new progress about Arylation. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Prasitwatcharakorn, Watcharapon published the artcileSynthesis of 4-Aryl-1,2-naphthoquinones via a conjugate addition-oxidation reaction catalyzed by p-toluenesulfonic acid, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is aryl naphthoquinone preparation; naphthoquinone arene conjugate addition oxidation para toluenesulfonic acid catalyst.

A catalytic conjugate addition-oxidation reaction of 1,2-naphthoquinones has been investigated. P-Toluenesulfnoic acid was found to be the most effective catalyst for the reaction. This developed method provides a short, simple, convenient, and low-cost synthesis of 4-aryl-1,2-naphthoquinones.

Results in Chemistry published new progress about Biaryls Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Albadi, Jalal published the artcileNew Procedure for the Highly Regioselective Aerobic Bromination of Aromatic Compounds Using Copper-based Nanocatalyst, HPLC of Formula: 151-10-0, the main research area is bromo aromatic compound preparation regioselective; aromatic compound aerobic bromination copper oxide catalyst.

A new procedure for the highly regioselective aerobic bromination of aromatic compounds RH (R = 4-hydroxyphenyl, 5-chloro-2-methoxyphenyl, 4-methoxynaphthalen-1-yl, etc.) in the presence of copper-based nanoparticles (CuO/ZnO nanocatalyst) under reflux condition is described. Mechanistic parameters are discussed and the plausible mechanism is proposed. Recyclability of the CuO/ZnO nanocatalyst has also been explored upon aerobic bromination of aromatic compounds

Letters in Organic Chemistry published new progress about Bromination catalysts (regioselective). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, HPLC of Formula: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Li, Yang published the artcileTrifluoromethyl Selenoxides: Electrophilic Reagents for C-H Trifluoromethylselenolation of (Hetero)Arene, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is selanyl hetero aryl trifluoromethyl regioselective preparation; hetero aryl methyl oxido trifluoromethyl selenonium carbon hydrogen trifluoromethylselenolation; trifluoromethyl selanyl aryl regioselective preparation; aromatic compound aryl methyl oxido trifluoromethyl selenonium carbon hydrogen; trifluoromethylselenolation.

Herein, designed and synthesized the new electrophilic trifluoromethylselenolation reagents, trifluoromethyl selenoxides I [X = H, CF3, CN], which were easy to prepare and easy-to-handle and were not moisture or air sensitive. The selenoxides are successfully applied to metal-free C-H trifluoromethylselenolation of a series of (hetero)arenes to gave ((trifluoromethyl)selanyl)aryl ArSeCF3 [Ar = 4-HOC6H4, 1H-indol-3-yl, (5-methoxycarbonyl-1H-pyrrol-3-yl), etc.].

Organic Letters published new progress about Bromoalkanes Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Liu, Shiwen published the artcileHydrogen-Bonding-Network-Assisted Regioselective Trifluoromethylthiolation and Sulfenylation of Electron-Rich (Hetero)arenes, SDS of cas: 151-10-0, the main research area is thioarene preparation regioselective; thiosuccinimide arene sulfenylation; trifluoromethyl thioarene preparation regioselective; trifluoromethylthio saccharin arene trifluoromethylthiolation.

An efficient and straightforward hydrogen-bonding-network-assisted regioselective sulfenylation of electron-rich arenes with N-thiosuccinimides was developed for the synthesis of thioarenes ArSR [R = c-hexyl, 4-MeC6H4, 2-FC6H4, etc.; Ar = 4-NMe2C6H4, 1-methylindol-3-yl, 5-MeO-1H-indol-3-yl, etc.]. This method was also used for the synthesis of ((trifluoromethyl)thio)arenes ArSCF3 via trifluoromethylthiolation of arenes using electrophilic N-(trifluoromethylthio)saccharin as SCF3 reagent. This catalyst-free protocol offered good yields for a wide range of arenes and showed good functional group tolerance without any protecting groups.

Asian Journal of Organic Chemistry published new progress about Cyclic imides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (N-thio). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zhang, Hao-Ran published the artcileDirect Arene Trifluoromethylation Enabled by a High-Valent CuIII-CF3 Compound, Related Products of isoquinoline, the main research area is arene heteroarene trifluoromethylation copper; Arenes; C−H Functionalization; High-Valent Copper Species; Radical Reaction; Trifluoromethylation.

Direct C-H trifluoromethylation of arenes and heteroarenes poses an important synthetic challenge that is highly desirable. High-valent CuIII-CF3 compounds have often been invoked in copper-mediated trifluoromethylation reactions, but the fundamental reactivity toward arenes is elusive. Herein, direct C-H trifluoromethylation of arenes/heteroarenes by a high-valent CuIII-CF3 compound is disclosed for the first time. The CuIII-CF3 compound serves CF3 radical and a CuII oxidant by homolytic cleavage of a CuIII-CF3 bond, which engage synergistically in a SEAr type reaction with arenes. The presence of K2S2O8 co-oxidant can significantly improve the reaction yields. This reaction shows good efficiency, broad functional group tolerance, and the potential in late-stage functionalization. The reactivity of high-valent CuIII-CF3 compounds disclosed in this study represents an important progress in organofluorine and CuIII chem.

Angewandte Chemie, International Edition published new progress about Heterocyclic aromatic compounds Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Related Products of isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Sakhdari, Mahnaz published the artcileSynthesis of novel triiodide ionic liquid based on quaternary ammonium cation and its use as a solvent reagent under mild and solvent-free conditions, SDS of cas: 151-10-0, the main research area is iodoarene preparation; arene iodination.

In this article, for the first time, N,N,N-triethyl-3-iodopropan-1-aminium triiodide was synthesized and utilized as both a reagent and a solvent in combination with H2O2 (35%) to convert aromatic compounds into their corresponding iodo derivatives The iodination was accomplished in the absence of organic solvents, and in most instances, water was the sole extraction solvent used. The consumed reagent N,N,N-triethyl-3- iodopropan-1-aminium iodide was comfortably recycled.

Heterocyclic Communications published new progress about Iodination. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Wu, Yaxing published the artcileElectrochemical and direct C-H methylthiolation of electron-rich aromatics, Safety of 1,3-Dimethoxybenzene, the main research area is thiomethylated aromatic compound preparation; electron rich aromatic compound electrochem methylthiolation.

The electrochem.-induced C-H methylthiolation of electron-rich aromatics for the synthesis of thiomethylated aromatics ArSR [R = Me, Et, n-Pr; Ar = 4-MeOC6H4, 4-MeNHC6H4, 2-MeO-1-naphthyl, etc.] was accomplished via a three component cross-coupling strategy. Potassium thiocyanate (KSCN) as both the supporting electrolyte and sulfur source and methanol as the methylation reagent were used. This protocol was versatile for various (hetero)aromatic compounds such as aniline, anisole and indole. The reaction proceeded under mild conditions without any metal catalyst, exogenous oxidant and highly toxic sulfur reagent. Importantly, such an electrochem.-induced methylthiolated reaction could be easily scaled up with good efficiency.

Green Chemistry published new progress about Methylsulfenylation. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Xu, Guangyang published the artcileAsymmetric Arylation of Diazoesters with Anisoles Enabled by Cooperative Gold and Phosphoric Acid Catalysis, Quality Control of 151-10-0, the main research area is alpha diaryl acetate preparation enantioselective gold phosphoric acid catalyst; diazoester anisole asym arylation.

An enantioselective carbene insertion into Csp2-H bond of anisole derivatives has been accomplished using an achiral gold complex and a chiral phosphoric acid as the catalytic system, providing a novel protocol for the synthesis of chiral α,α-diaryl acetates. DFT calculations reveal the reactivity and the origin of the enantioselectivity of this reaction.

Organic Letters published new progress about Anisoles Role: RCT (Reactant), RACT (Reactant or Reagent). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Quality Control of 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem