Tag: M.W=100-150

Tran, Phuong Hoang published the artcileMagnetically recoverable γ-Fe2O3 nanoparticles as a highly active catalyst for Friedel-Crafts benzoylation reaction under ultrasound irradiation, Category: isoquinoline, the main research area is recoverable magnetic iron oxide nanocatalyst preparation surface structure; arene benzoyl chloride iron oxide nanocatalyst Friedel Crafts benzoylation; diaryl ketone regioselective preparation ultrasonication irradiation green chem.

A simple, facile and efficient method was developed for the Friedel-Crafts benzoylation of arenes using magnetic γ-Fe2O3 nanoparticles under solvent-free sonication. The γ-Fe2O3 nanoparticles were used as an efficient and magnetically recoverable catalyst for the synthesis of aromatic ketones in good to excellent yields at room temperature under solvent-free conditions. The reaction occurred with high regioselectivity under mild condition. The magnetic γ-Fe2O3 nanoparticles were economically synthesized in large-scale, easily separated from the reaction mixture by an external magnet and able to be reused several times without significant loss of the catalytic performance, which made them easy application to industrial processes.

Arabian Journal of Chemistry published new progress about Aryl ketones Role: SPN (Synthetic Preparation), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Gao, Hui published the artcileElectrochemical benzylic C-H arylation of xanthenes and thioxanthenes without a catalyst and oxidant, Safety of 1,3-Dimethoxybenzene, the main research area is aryl xanthene preparation; xanthene arene electrochem arylation reaction; arylthioxanthene preparation; arene thioxanthene electrochem arylation reaction.

A catalyst-free and oxidant-free C-H arylation of xanthenes and thioxanthenes I (R1 = H, Me, OH, Cl, etc.; R2 = H, OMe; R3R4 = -CH=CH-CH=CH-; X = O, S) using electrochem. has been developed, which affords a number of cross-coupling products II (R5 = 4-methoxyphenyl, 4-methoxy-3-methylphenyl, 4-methoxy-3,5-dimethylphenyl, 2H-1,3-benzodioxol-5-yl, etc.) in moderate to good yields. This method is atom- and step-economical as it uses cheap and easily available arenes and heteroarenes as partners directly and the C(sp2)-H/C(sp3)-H type cross-coupling reaction.

Organic Chemistry Frontiers published new progress about Arylation. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Safety of 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Kanemoto, Kazuya published the artcileAcid-Mediated Sulfonylthiolation of Arenes via Selective Activation of SS-Morpholino Dithiosulfonate, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is thiosulfonate preparation regioselective; arene morpholinotoluene dithioperoxosulfonate desulfurilative sulfonylthiolation trifluoro acetic acid.

A trifluoroacetic-acid-mediated desulfurilative sulfonylthiolation of arenes RH (R = 4-methoxyphenyl, thiophen-2-yl, 6-bromo-2-hydroxynaphthalen-1-yl, etc.) using SS-morpholino 4-toluene(dithioperoxo)sulfonate is described. This system is based on selective activation of the morpholino group over the tosyl group of the doubly transformable sulfur surrogate. Mechanistic studies suggested that the reaction proceeds through electrophilic aromatic substitution followed by sulfur extrusion. The wide substrate scope of this reaction and the transformability of the resulting thiosulfonates RSTs enable expeditious access to divergent multifunctionalized sulfides.

Organic Letters published new progress about Bond formation catalysts. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Bora, Pranjal P. published the artcileShielding Effect of Micelle for Highly Effective and Selective Monofluorination of Indoles in Water, SDS of cas: 151-10-0, the main research area is indole fluoro bisbenzenesulfonimide water surfactant medium regioselective monofluorination; fluoroindole preparation green chem; arene fluorobenzenesulfonimide water surfactant medium regioselective monofluorination; fluoroarene preparation green chem; E-factor; fluorination; green chemistry; micelles; sustainability.

Highly selective direct monofluorination of indoles and arenes was developed through an approach that allows site-specific solubility of substrate and fluorine source in the micelle. This approach was highly selective for a broad range of substrates with excellent functional group tolerance. Differences in binding constant and solubility of indoles and arenes in the micelle allowed the fine-tuning of selectivity. Control experiments suggested a radical pathway and provided insight into the role of micelles of the environmentally benign amphiphile PS-750-M. Dynamic light scattering experiments strongly indicated the site-specific solubility of the substrate and fluorine source. The methodol. was successfully adapted to gram scale and the E-factor established from a recycle study indicated that the process was environmentally responsible and sustainable.

ChemSusChem published new progress about Fluorination, regioselective. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, SDS of cas: 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Lemmens, Vincent published the artcileRu-Bipyridine Entrapped in the Supercages of EMC-1 Faujasite as Catalyst for the Trifluoromethylation of Arenes, Quality Control of 151-10-0, the main research area is hetero arene trifluoromethylation ruthenium bipyridine supercage faujasite catalyst photochem; Ru(bipy)32+; faujasite; heterogeneous catalysis; photocatalysis; trifluoromethylation.

Trifluoromethyl (CF3) groups are versatile structural motifs especially in the field of agrochems. and pharmaceuticals. However, current trifluoromethylation reactions are generally associated with stoichiometric amounts of transition metals/metal oxidants, homogeneous catalysts, high temperatures, and expensive trifluoromethylating agents. In this work, the homogeneous photocatalyst Ru(bipy)32+ is entrapped in the pores of a faujasite support (EMC-1) via a “”ship-in-a-bottle”” strategy. The formation of the coordination compound was confirmed by Fourier transform IR (FTIR), UV-Vis spectroscopy, and X-ray absorption spectroscopy (XAS). Due to its high stability toward acidified environments, this single-site heterogeneous catalyst is suitable for the trifluoromethylation of synthetically interesting (hetero)arenes under visible-light irradiation at room temperature Furthermore, the heterogeneous catalyst could efficiently be reused for at least three times with minimal catalyst leaching/deactivation.

ACS Applied Materials & Interfaces published new progress about Heterocyclic compounds Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Quality Control of 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zhou, Cong published the artcilePhotoredox-Catalyzed α-Aminomethyl Carboxylation of Styrenes with Sodium Glycinates: Synthesis of γ-Amino Acids and γ-Lactams, Safety of 4-Methoxy-N-methylaniline, the main research area is arylaminoarylbutanoic acid arylbutyrolactam regioselective preparation; ruthenium photoredox catalyst regioselective aminomethylcarboxylation arylaminoglycine aryl alkene; iridium photoredox catalyst regioselective aminomethylcarboxylation lactamization arylaminoglycine aryl alkene.

A visible-light photoredox-catalyzed reductive α-aminomethyl carboxylation of styrenes and 1,1-diarylalkenes with sodium N-arylglycinates and CO2 has been developed to synthesize a series of α,α-disubstituted γ-amino acids such as MePhNCH2CH2CPh2CO2H and γ-lactams such as 1,3,3-triphenyl-2-pyrrolidinone with high efficiency and regioselectivity. Notably, CO2 released from the decarboxylation step can be reused for the subsequent carboxylation. Distinct from the previous reactions with the same type of substrates leading to simple decarboxylation and olefin hydroalkylation, this process involves addnl. CO2 sequestration, thus leading to olefin α-aminomethyl carboxylation. These findings not only provide new access to α,α-disubstituted γ-amino acids and γ-lactams but also serve as a proof of concept for CO2 reutilization in decarboxylation reactions.

Organic Letters published new progress about Aminomethylation (regioselective, photochem., carboxylation). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Safety of 4-Methoxy-N-methylaniline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Kawajiri, Takahiro published the artcileChemoselective Nucleophilic Functionalizations of Aromatic Aldehydes and Acetals via Pyridinium Salt Intermediates, Recommanded Product: 1,3-Dimethoxybenzene, the main research area is aldehyde aryl arene trialkylsilyl triflate bipyridyl chemoselective nucleophilic substitution; acetal aryl arene trialkylsilyl triflate bipyridyl chemoselective nucleophilic substitution; allylsilane aldehyde aryl trialkylsilyl triflate bipyridyl chemoselective nucleophilic substitution; ether benzyl silyl preparation.

The development of a novel chemoselective functionalization can diversify the strategy for synthesizing the target mols. The perfect chemoselectivity between aromatic and aliphatic aldehydes is difficult to achieve by the previous methods. The aromatic aldehyde-selective nucleophilic addition in the presence of aliphatic aldehydes was newly accomplished. Namely, the aromatic aldehyde-selective nucleophilic addition using arenes and allyl silanes proceeded in the presence of trialkylsilyl triflate and 2,2′-bipyridyl, while the aliphatic aldehydes completely remained unchanged. The reactive pyridinium-type salt intermediate derived from an aromatic aldehyde chemoselectively underwent the nucleophilic substitution. Moreover, the aromatic acetals as the protected aldehydes could be directly transformed into similar pyridinium salt intermediates, which reacted with various nucleophiles coexisting with the aliphatic aldehydes.

Journal of Organic Chemistry published new progress about Alkoxysilanes Role: SPN (Synthetic Preparation), PREP (Preparation) (benzyl). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Recommanded Product: 1,3-Dimethoxybenzene.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Phan Thi Thanh, Nga published the artcileSynthesis of Oxindole Derivatives via Intramolecular C-H Insertion of Diazoamides Using Ru(II)-Pheox Catalyst, Synthetic Route of 5961-59-1, the main research area is oxindole preparation regioselective; diazoacetamide preparation insertion reaction ruthenium catalyst.

This work presented the efficient intramol. aromatic C-H insertion of diazoacetamide. The diazo compounds (except for 1k) were converted into their corresponding oxindoles via an intramol. C-H insertion reaction in the presence of a Ru catalyst. The Ru-Pheox catalyst was shown to be highly efficient in this transformation in terms of the regioselectivity, producing the desired products in excellent yield (99%). The efficiency of the Ru catalyst reached 580 (TON) and 156 min-1 (TOF).

Tetrahedron published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Synthetic Route of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Jie, Yu published the artcileIdentification of Key Volatiles Differentiating Aromatic Rice Cultivars Using an Untargeted Metabolomics Approach, Application In Synthesis of 151-10-0, the main research area is Oryza aromatic cultivar metabolomics volatile compound; acetoin; aromatic rice; differential metabolites.

Non-aromatic rice is often sold at the price of aromatic rice to increase profits, seriously impairing consumer experience and brand credibility. The assessment of rice varieties origins in terms of their aroma traits is of great interest to protect consumers from fraud. To address this issue, the study identified differentially abundant metabolites between non-aromatic rice varieties and each of the three most popular aromatic rice varieties in the market using an untargeted metabolomics approach. The 656 metabolites of five rice grain varieties were determined by headspace solid-phase extraction gas chromatog.-mass spectrometry, and the multivariate analyses were used to identify differences in metabolites among rice varieties. The metabolites most differentially abundant between Daohuaxiang 2 and non-aromatic rice included 2-acetyl-1-pyrroline and acetoin; the metabolites most differentially abundant between Meixiangzhan 2 and non-aromatic rice included acetoin and 2-methyloctylbenzene,; and the metabolites most differentially abundant between Yexiangyoulisi and non-aromatic rice included bicyclo[4.4.0]dec,1-ene-2-isopropyl-5-methyl-9-methylene and 2-methylfuran. Overall, acetoin was the metabolite that was most differentially abundant between the aromatic and non-aromatic rice. This study provides direct evidence of the outstanding advantages of aromatic rice and acts a reference for future rice authentication processes in the marketplace.

Metabolites published new progress about Aldehydes Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Application In Synthesis of 151-10-0.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Choo, Kenny S. O. published the artcileAroma-volatile profile and its changes in Australian grown black Perigord truffle (Tuber melanosporum) during storage, Category: isoquinoline, the main research area is Tuber acetone acetaldehyde toluene formic acid 2 butenal Australia.

Black Perigord truffle (Tubermelanosporum) is one of the most expensive fungi in the world that appreciated by gourmets. Studies have indicated the impact of growing location and soil microorganisms on the aroma profile of truffle. The aroma profile of West Australian black Perigord truffle (Tuber melanosporum) has not been previously reported, which was studied over a 14 day storage period. Sixty-four compounds were identified in all truffle samples. Significant changes (P > 0.05) were observed in 11 key volatiles (carbon dioxide, acetaldehyde, 2-butanone, 3-methyl-1-butanal, toluene, 2-butenal, formic acid 2-Me Bu ester, 3-methyl-1-butanol, 6-methyl-2-heptanol, 3-octanol and DMSO) over time. Comparison of these results against published aroma profile of European grown black Perigord truffle identified number of significant similarities and differences were also detected. DMSO, a compound previously identified in European grown white truffle (Tuber magnatum), was detected. Principle component anal. (PCA) showed that the major changes in the truffle aroma profile took place in the first 7 days of storage.

International Journal of Food Science and Technology published new progress about Soils. 151-10-0 belongs to class isoquinoline, name is 1,3-Dimethoxybenzene, and the molecular formula is C8H10O2, Category: isoquinoline.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem