Phan Thi Thanh, Nga’s team published research in Tetrahedron in 2020-10-23 | CAS: 5961-59-1

Tetrahedron published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Synthetic Route of 5961-59-1.

Phan Thi Thanh, Nga published the artcileSynthesis of Oxindole Derivatives via Intramolecular C-H Insertion of Diazoamides Using Ru(II)-Pheox Catalyst, Synthetic Route of 5961-59-1, the main research area is oxindole preparation regioselective; diazoacetamide preparation insertion reaction ruthenium catalyst.

This work presented the efficient intramol. aromatic C-H insertion of diazoacetamide. The diazo compounds (except for 1k) were converted into their corresponding oxindoles via an intramol. C-H insertion reaction in the presence of a Ru catalyst. The Ru-Pheox catalyst was shown to be highly efficient in this transformation in terms of the regioselectivity, producing the desired products in excellent yield (99%). The efficiency of the Ru catalyst reached 580 (TON) and 156 min-1 (TOF).

Tetrahedron published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent). 5961-59-1 belongs to class isoquinoline, name is 4-Methoxy-N-methylaniline, and the molecular formula is C8H11NO, Synthetic Route of 5961-59-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem