Tag: M.W=150-200

Abhilash, Vishwanathan published the artcileChemoselective hydrosilylation of carboxylic acids using a phosphine-free ruthenium complex and phenylsilane, COA of Formula: C9H10O3, the main research area is alc preparation chemoselective; carboxylic acid phenylsilane agent hydrosilylation tandem ruthenium complex catalyst.

A highly chemoselective hydrosilylation of carboxylic acids RC(O)OH [R = 4-methoxyphenylmethyl, benzo[1,3]dioxol-5-yl, benzofuran-6-yl, etc.] was achieved using a bench-stable, phosphine-free Ru-complex tethered with hemi-labile thiophene ligands as the catalyst, employing phenylsilane as the reducing agent. The methodol. was further elaborated towards the one-pot synthesis of 1H-indole and 3,4-dihydro-2H-benzo[1,4]oxazine via tandem reduction/cyclization of acid and nitro group.

Journal of Organometallic Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 104-01-8 belongs to class isoquinoline, name is 4-Methoxyphenylacetic acid, and the molecular formula is C9H10O3, COA of Formula: C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Scrivanti, Alberto published the artcileArylation of β-methallyl alcohol catalyzed by Pd(OAc)2 in combination with P(t-Bu)3: application to fragrance synthesis, Recommanded Product: 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, the main research area is arylmethylpropana helional canthoxal lilial preparation fragrance; methallyl alc arylation aryl bromide catalyst palladium phosphine.

Pd(OAc)2 in combination with P(t-Bu)3 catalyzes the coupling of β-methallyl alc. with 1-bromo-3,4-(methylenedioxy)benzene (I), 1-bromo-4-methoxybenzene (II), or 1-bromo-4-tert-butylbenzene (III). The reaction affords the corresponding 2-methyl-3-aryl-propanals, which are valuable floral fragrances. With I or II high reaction rates are obtained at 130 °C using NMP/water mixtures and an inorganic base such as Na2CO3. The chemoselectivity of the reaction is almost complete, so that the process appears practically feasible. In contrast, the coupling of β-methallyl alc. with III proceeds with low reaction rates.

Tetrahedron published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 1205-17-0 belongs to class isoquinoline, name is 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde, and the molecular formula is C11H12O3, Recommanded Product: 2-Methyl-3-(3,4-methylenedioxyphenyl)propionaldehyde.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Ud Din, Zia published the artcileOptimized one-pot synthesis of monoarylidene and unsymmetrical diarylidene cycloalkanones, Computed Properties of 86-51-1, the main research area is monoarylidene diarylidene cycloalkanone preparation green chem; ketone condensation aryl aldehyde dimethylammonium dimethylcarbamate catalyst.

Ionic liquid dimethylammonium dimethylcarbamate (DIMCARB) catalyzed reaction for the synthesis of monoarylidene cycloalkanones I (X = nothing, CH2, O; R1 = Ph, 2-MeC6H4, 4-MeOC6H4, 1,3-benzodioxol-5-yl, etc.) and unsym. diarylidene cyclohexanones II (R2 = Ph, 4-ClC6H4, 4-BrC6H4, 4-O2NC6H4, 4-FC6H4, 4-Me2NC6H4) has been developed. Both cyclic and acyclic ketones were reacted with a variety of electron-donating and withdrawing-substituted aldehydes in the presence of a catalytic amount of DIMCARB in a green solvent (aqueous ethanol) providing the corresponding monoarylidene ketones, e.g. I, in low to excellent yields. Subsequent condensation of 2-(4-methoxybenzylidene)cyclohexanone with various aromatic aldehydes under basic conditions allowed for the preparation of unsym. diarylidene cyclohexanones II. This synthetic methodol. provides mild, efficient, and environmentally friendly access to unsym. curcuminoid analogs, avoiding the use of excess catalysts, chlorinated organic solvent, and high temperature reaction. It is green and environmentally sound alternative to the existing protocols for the synthesis of pharmaceutically important unsym. natural product analogs.

Arabian Journal of Chemistry published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Computed Properties of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Zare-Akbari, Zhila published the artcileA novel nanomagnetic solid acid catalyst for the synthesis of new functionalized bis-coumarin derivatives under microwave irradiations in green conditions, Application In Synthesis of 86-51-1, the main research area is biscoumarin preparation green chem microwave irradiation; aryl aldehyde hydroxycoumarin condensation nanomagnetic sulfosalicylic acid catalyst.

In this study, a novel, green, environmentally friendly and magnetically heterogeneous catalyst based on the immobilization of sulfosalicylic acid onto Fe3O4 nanoparticles (Fe3O4@sulfosalicylic acid MNPs) is reported. The bis-coumarin analogs I (Ar = Ph, 5-nitrothiophen-2-yl, 6-methylpyridin-2-yl, etc.) were synthesized in high yield using the reaction of 1 equiv of aryl aldehydes ArCHO with 2 equiv of 4-hydroxycoumarin in water under microwave irradiation conditions. SEM, transmission electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction, thermogravimetric anal., dynamic light scattering, vibrating sample magnetometry, Fourier transform IR spectroscopy, UV-visible absorption, and Brunauer-Emmett-Teller techniques confirmed the successful synthesis of the catalyst. The main attractive characteristics of the presented green protocol are very short reaction times (10-15 min), excellent yields, and the avoidance of hazardous or toxic reagent and solvents. Thermal durability, easy separation, and high reusability are important advantages of the new catalyst in comparison to other catalysts.

Applied Organometallic Chemistry published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Application In Synthesis of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Alizadeh, Abdolhamid published the artcileGreen and Fast Synthesis of 2-Arylidene-indan-1,3-diones Using a Task-Specific Ionic Liquid, Recommanded Product: 2,3-Dimethoxybenzaldehyde, the main research area is arylidenindanedione green synthesis condensation task specific ionic liquid.

A novel method for condensation reaction of indan-1,3-dione with various aldehydes which are efficiently catalyzed by a task-specific ionic liquid, 2-hydroxyethylammonium formate, to provide the corresponding 2-arylidenindane-1,3-diones has been developed. This green, low-cost, high-yield, and fast reaction takes place at room temperature without the use of any solvent and catalyst. A plausible reaction mechanism that involves ionic liquid-assisted activation is also discussed. This work is the first report of ionic liquids as a reaction medium and catalyst for the synthesis of 2-arylidenindane-1,3-diones.

ACS Omega published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Recommanded Product: 2,3-Dimethoxybenzaldehyde.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Ghasemzadeh, Mohammad Ali published the artcileMIL-53(Fe) Metal-Organic Frameworks (MOFs) as an Efficient and Reusable Catalyst for the One-Pot Four-Component Synthesis of Pyrano[2,3-c]-pyrazoles, Computed Properties of 86-51-1, the main research area is pyranopyrazole preparation green chem; malononitrile hydrazine hydrate ethyl acetoacetate aldehyde condensation.

A novel and simple approach for the efficient and rapid synthesis of pyrano[2,3-c]-pyrazoles I (Ar = Ph, 4-MeC6H4, 4-ClC6H4, etc.) has been accomplished via the four-component condensation reaction of malononitrile, hydrazine hydrate, Et acetoacetate, and substituted aldehydes using MIL-53(Fe) metal-organic framework (MOF) as a catalyst in ethanol at room temperature Recycling studies have shown that the MIL-53(Fe) can be readily recovered and reused six times without significant loss of its activity. The present protocol offers the advantages including short reaction times, simple workup, high yields, elimination of toxic solvents, no chromatog. purification and recoverability of the catalyst. Also, the catalyst was fully characterized by SEM, EDX, FT-IR, XRD, TGA and TEM anal.

Applied Organometallic Chemistry published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Computed Properties of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Demidov, Maxim R. published the artcileThree-component synthesis of 2-acyl-2,3-dihydro-4H-thiochromeno[4,3-b]furan-4-ones and their reductive rearrangement into 4H,5H-thiochromeno[4,3-b]pyran-5-ones, Synthetic Route of 86-51-1, the main research area is thiochromenopyranone preparation; acyl thiochromenofuranone preparation reductive rearrangement; pyridinium acyl methylide aldehyde hydroxythiocoumarin multicomponent.

Three-component condensation of in situ generated pyridinium acyl methylides with aromatic aldehydes and 4-hydroxythiocoumarin led to a series of 2-acyl-dihydro-thiochromenofuranones I [R1 = Ph, 3-O2NC6H4, 2-naphthyl, etc.; R2 = Ph, 4-MeC6H4, 4-MeOC6H4, etc.]. The reaction proceeded diastereoselectively with the formation of trans-isomers and represented a cascade process involving the Knoevenagel condensation, carbo-Michael reaction and intramol. nucleophilic substitution. The subsequent redox rearrangement of 2-acyl-2,3-dihydro-4H-thiochromeno[4,3-b]furan-4-ones by the action of Zn and ZrCl4 granted access to 4H,5H-thiochromeno[4,3-b]pyran-5-ones II.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Synthetic Route of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Imrankhan, Mohammed published the artcileKSCN and K2CO3 mediated one-pot synthesis of cyclopropanyl coumarin derivatives, Application In Synthesis of 86-51-1, the main research area is bromomethylcoumarin arylaldehyde carbonitrile diastereoselective three component cyclization green chem; coumarinyl arylcyclopropanyl carbonitrile preparation.

A novel and efficient one-pot method was developed for the synthesis of 2-(2-oxochromen-4-yl)cyclopropanecarbonitriles I [R1 = 6-Me, 6-Cl, 7-benzyl, etc.; R2 = Ph, 4-oxochromen-2-yl, 1-methylimidazol-2-yl, etc.; R3 = NC, ethoxycarbonyl] by the cyclization of 4-bromomethylcoumarins, aryl aldehydes and active methylene groups in 1:1 acetonitrile and water solvent in the presence of KSCN and K2CO3 as a catalyst at room temperature for 2-5 h. The significant attraction of this procedure was, environmentally benign, simple procedure, the ready accessibility of the catalyst, excellent yield and mild reaction conditions. The structure of the target mol. I [R1 = 6,8-di-Me, R2 = 2,3-dimethoxyphenyl, R3 = NC] was confirmed by X-ray diffraction. The structures of the synthesized compounds I were confirmed by spectral methods viz. IR, 1H NMR, 13C NMR, mass spectral anal. and X-ray diffraction studies.

Journal of Chemical Sciences (Berlin, Germany) published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Application In Synthesis of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Maddila, Suresh published the artcileA facile and environmental-friendly protocol for the synthesis of methyleneisoxazole-5(4H)-ones catalyzed by CeO2/TiO2 under ultrasonic irradiation, Formula: C9H10O3, the main research area is cerium titanium oxide nanocomposite preparation catalyst methyleneisoxazoleone ultrasonic preparation.

A novel and efficient nanocomposite is synthesized by deposition-precipitation approach, characterized by FE-SEM, SEM-EDX, P-XRD, TEM, TGA and BET analyses. P-XRD and N2 sorption investigations of 2.5 mol% CeO2/TiO2 confirmed the amorphous mesoporous nature of CeO2/TiO2, which possessed a sp. surface area of 110.6 m2.g-1 and an average pore size 83 nm. Then, SEM and TEM ascertained the disordered pores in their morphol. Further, the catalytic activity of the prepared nanocomposite was applied for the synthesis of methyleneisoxazole-5(4H)-one analog via one-pot and multicomponent reaction of substituted aldehyde, Et acetoacetate and hydroxylamine in the presence of ultrasound irradiation under eco-friendly manner. Simple handling, utilization of readily accessible starting materials, elimination of toxic solvents, environmental-friendly, easy workup, cleaner reaction profile, high product yields (94-99%) and short reaction times (≤10 mints), recyclability, and reusability are several benefits of this approach.

Inorganic Chemistry Communications published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Formula: C9H10O3.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem

Ganja, Himavathi published the artcileY2O3/HAp, a sustainable catalyst for novel synthesis of furo[3,4-b]chromenes derivatives via green strategy, Computed Properties of 86-51-1, the main research area is yttria doped hydroxyapatite preparation green catalyst preparation furochromene derivative; aldehyde multicomponent reaction hydroxyfuranone dimethylcyclohexanedione.

A green, facile and multicomponent reaction for the preparation of furo[3,4-b]chromenes using a recoverable and reusable yttria doped hydroxyapatite (Y2O3/HAp) solid material as the heterogeneous catalyst is described. The reaction progresses with mixing the aldehyde, 4-hydroxyfuran-2(5H)-one, 5,5-dimethylcyclohexane-1,3-dione and Y2O3/HAp at R.T. in ethanol solvent media to obtain the desired target mols. in excellent yields (91-98%). The proposed approach shows noteworthy benefits such as ecofriendly, non-toxic solvents, easy handling, short reaction time (10 min), simple workup procedure, avoiding column chromatog. and reusability of the catalyst, proving vital green chem. principles.

Inorganic Chemistry Communications published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Computed Properties of 86-51-1.

Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem