Ghasemzadeh, Mohammad Ali published the artcileMIL-53(Fe) Metal-Organic Frameworks (MOFs) as an Efficient and Reusable Catalyst for the One-Pot Four-Component Synthesis of Pyrano[2,3-c]-pyrazoles, Computed Properties of 86-51-1, the main research area is pyranopyrazole preparation green chem; malononitrile hydrazine hydrate ethyl acetoacetate aldehyde condensation.
A novel and simple approach for the efficient and rapid synthesis of pyrano[2,3-c]-pyrazoles I (Ar = Ph, 4-MeC6H4, 4-ClC6H4, etc.) has been accomplished via the four-component condensation reaction of malononitrile, hydrazine hydrate, Et acetoacetate, and substituted aldehydes using MIL-53(Fe) metal-organic framework (MOF) as a catalyst in ethanol at room temperature Recycling studies have shown that the MIL-53(Fe) can be readily recovered and reused six times without significant loss of its activity. The present protocol offers the advantages including short reaction times, simple workup, high yields, elimination of toxic solvents, no chromatog. purification and recoverability of the catalyst. Also, the catalyst was fully characterized by SEM, EDX, FT-IR, XRD, TGA and TEM anal.
Applied Organometallic Chemistry published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 86-51-1 belongs to class isoquinoline, name is 2,3-Dimethoxybenzaldehyde, and the molecular formula is C9H10O3, Computed Properties of 86-51-1.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem