In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 63006-93-9, name is (1,2,3,4-Tetrahydroisoquinolin-3-yl)methanol, introducing its new discovery. Recommanded Product: (1,2,3,4-Tetrahydroisoquinolin-3-yl)methanol
Utilizing the intramolecular Fukuyama-Mitsunobu reaction for a flexible synthesis of novel heterocyclic scaffolds for peptidomimetic drug design
We report the synthesis of the novel scaffolds pyrazino[1,2-b]isoquinoline and pyrrolo[1,2-a]pyrazine displaying the somatostatin pharmacophores. Both classes of compounds contain a pyrazine heterocycle, which can be prepared in a straightforward manner utilizing an intramolecular Fukuyama-Mitsunobu reaction. As both the families derive from amino acids, they can be accessed in high optical purity.
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Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem