Downstream synthetic route of 63927-23-1

As the paragraph descriping shows that 63927-23-1 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.63927-23-1,5-Bromo-8-nitroisoquinoline,as a common compound, the synthetic route is as follows.

EXAMPLE 10 STR10 A mixture of 5-bromo-8-nitroisoquinoline (0.99 g, 3.91 mmol) and dimethylsulfate (0.41 mL) in anhydrous DMF (20 mL) was heated at 80 C. for 24 h. After removing the DMF in vacuo, the isoquinoline methylammonium salt was obtained (used without further purification).

As the paragraph descriping shows that 63927-23-1 is playing an increasingly important role.

Reference£º
Patent; NeuroSearch A/S; US5436250; (1995); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem