Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Computed Properties of C9H9NO2. Introducing a new discovery about 22245-98-3, Name is 6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one
3-(4-(6-Fluoroalkoxy-3,4-dihydroisoquinoline-2(1H)-yl)cyclohexyl)-1H-indole-5-carbonitriles for SERT imaging: Chemical synthesis, evaluation in vitro and radiofluorination
Aminocyclohexyl indoles bind with high affinity and specificity toward the serotonin transporter (SERT). Based on this structural lead, we designed fluoroalkoxydihydroisoquinoline-cyclohexyl indole carbonitriles for future application as 18F-labeled tracers for SERT imaging by PET. Six compounds, three pairs of cis- and trans-isomer derivatives, respectively, were synthesized and evaluated in vitro. The chemistry of the new compounds, their affinity and specificity data, the general route to the phenolic precursor for labeling, and the successful 18F-fluoroalkylation of one pair of compounds are described herein.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Computed Properties of C9H9NO2, you can also check out more blogs about22245-98-3
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem