Reference of 3382-18-1, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 3382-18-1, 6,7-Dimethoxy-3,4-dihydroisoquinoline, introducing its new discovery.
A concise total synthesis of (+)-tetrabenazine and (+)-alpha- dihydrotetrabenazine
Highly concise asymmetric total syntheses of (+)-tetrabenazine (1), a drug for the treatment of chorea associated with Huntington’s disease, and of (+)alpha-dihydrotetrabenazine (2), an active metabolite of 1, have been accomplished. Our synthetic route features a trans-selective enol etherification, followed by an unprecedented cation-dependent aza-Claisen rearrangement to establish the carbon framework and two stereogenic centers of tetrabenazine. The syntheses consist of seven steps (34% overall yield) for (+)-2 and eight steps (22% overall yield) for (+)-l.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 3382-18-1. In my other articles, you can also check out more blogs about 3382-18-1
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem