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Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of Isoquinoline-5-carbaldehyde, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent£¬Which mentioned a new discovery about 80278-67-7

Catalytic alpha-Selective Deuteration of Styrene Derivatives

We report an operationally simple protocol for the catalytic alpha-deuteration of styrenes. This process proceeds via the base-catalyzed reversible addition of methanol to styrenes in DMSO-d6 solvent. The concentration of methanol is shown to be critical for high yields and selectivities over multiple competing side reactions. The synthetic utility of alpha-deuterated styrenes for accessing deuterium-labeled chiral benzylic stereocenters is demonstrated.

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Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem