Reference of 521284-21-9, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 521284-21-9, Name is (R)-2-((4-Nitrophenethyl)amino)-1-phenylethanol hydrochloride, SMILES is O=[N+](C1=CC=C(C=C1)CCNC[C@H](O)C2=CC=CC=C2)[O-].[H]Cl, belongs to isoquinoline compound. In a article, author is Ito, C, introduce new discover of the category.
Chemopreventive activity of isoquinoline alkaloids from Corydalis plants
Eighteen isoquinoline alkaloids including protoberberines (1-12), benzophenanthridines (13-16) and an aporphine (17) isolated from plants of Corydalis species (Fumariaceae) were tested for inhibitory effects on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoylphorbol 13-acetate in Raji cells. In a primary screening test, all of the isoquinoline alkaloids showed inhibitory activity with the IC50 values being in the range of 140-410 mol ratio/32 pmol TPA. The data demonstrate that these isoquinoline alkaloids might be valuable as anti-tumor promoters.
Reference of 521284-21-9, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 521284-21-9 is helpful to your research.
Reference:
Isoquinoline – Wikipedia,
,Isoquinoline | C9H7N – PubChem