Brief introduction of 34784-05-9

34784-05-9, 34784-05-9 6-Bromoisoquinoline 313681, aisoquinoline compound, is more and more widely used in various fields.

34784-05-9, 6-Bromoisoquinoline is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

A mixture of 6-bromoisoquinoline (208 mg, 1 mmol), bis(pinacolato)diboron (279 mg, 1.1mmol), KOAc (323 mg, 3.3 mmol) and Pd(dppf)2Ci2 (73 mg, 0.1 mmol) in DMSO (3 ml) was heated ina microwave for 10 min at 160C. The mixture was diluted with water (20 ml) and extracted with10 EtOAc (4 x 20 ml). The combined EtOAc was washed with water (15 ml) and brine (15 ml) then dried(Na2S04). The solvent was removed to give the titled compound which was used directly for nextstep.

34784-05-9, 34784-05-9 6-Bromoisoquinoline 313681, aisoquinoline compound, is more and more widely used in various fields.

Reference£º
Patent; LEXICON PHARMACEUTICALS, INC.; BI, Yingzhi; CARSON, Kenneth Gordon; CIANCHETTA, Giovanni; GREEN, Michael Alan; KUMI, Godwin; LIANG, Zhi; LIU, Ying Jade; MAIN, Alan; ZHANG, Yulian; ZIPP, Glenn Gregory; WO2013/134219; (2013); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem