Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Product Details of 3382-18-1. Introducing a new discovery about 3382-18-1, Name is 6,7-Dimethoxy-3,4-dihydroisoquinoline
AUXILIARY SILICON IN REGIOSELECTIVE COBALT CATALIZED PROTOBERBERINE SYNTHESES
eta5-Cyclopentadienyl dicarbonyl cobalt catalyzes the cocyclization of 1,2-bis(propargyl)-1,2,3,4-tetrahydroisoquinolines 4b and 5 with alkynes to provide a novel synthetic entry into the tetrahydroprotoberberine nucleus.By judicious choice of trimethylsilyl substituents, regiocontrol in the D-ring can be achieved.Reaction of 4b with benzonitrile in the presence of the catalyst furnishes the rare isoquino<2,1-b>-2,6-naphthyridine framework, also regioselectively.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Product Details of 3382-18-1, you can also check out more blogs about3382-18-1
Reference£º
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem