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A gene delivery system (by machine translation)
The invention discloses gene nano liposome carrier Isoquinoline – 3 – acyl – RGDV (IRV) and IRV/STAT3 – siRNA preparation method of gene delivery system, in the present invention IRV/STAT3 – siRNA gene delivery system consists of a liposome carrier with IRV STAT3 – siRNA, protamines, calf Thymus DNA according to proportion, with slow release and targeting; the invention to lung cancer A549 cell strain is model to evaluate the complex cell transfection efficiency, in vitro anti-tumor activity, and mRNA level and protein at the level of gene silencing efficiency and cell mechanism, result display IRV/STAT3 – siRNA gene delivery system than every group has more excellent anti-tumor activity and gene silencing efficiency. Under the invention to S180 shui liu the abdomen of the mouse as a model to evaluate the IRV/STAT3 – siRNA gene delivery system of the anti-tumor activity, the result shows that 100% IRV/STAT3 – siRNA group has anti-tumor effect. (by machine translation)
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 6624-49-3, you can also check out more blogs about6624-49-3
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H1667N – PubChem