19493-44-8, Name is 1-Chloroisoquinoline, belongs to isoquinoline compound, is a common compound. Computed Properties of C9H6ClNIn an article, once mentioned the new application about 19493-44-8.
The Suzuki?Miyaura cross-coupling (SMC) reactions of several heteroaryl chlorides, benzyl chlorides, and aryl acid chlorides with (hetero)arylboron reagents have been investigated in the presence of [Pd(HL1)(PPh3)Cl2] (I) [HL1 = 3-[(2,6-diisopropylphenyl)-1-imidazolio]-2-quinoxalinide] as catalyst and K2CO3 as base in neat water. The synthesis of the heterocycle-containing biaryls required the addition of 2 mol-% of a phosphine ligand (PPh3 or X-Phos). A combination of more than 115 substrates were screened and it was found that I is a versatile catalyst that can produce heterocycle-containing biaryls, diarylmethanes, and benzophenones in moderate-to-excellent yields.
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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H1433N – PubChem