Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. category: isoquinoline. Introducing a new discovery about 34784-05-9, Name is 6-Bromoisoquinoline
An efficient Rh2(II,II)-catalyzed reaction has been developed under mild conditions. This synthetic method proceeds through iodination/oxidation of readily available isoquinolinium iodide salts under aerobic conditions with good to excellent yields. 4-Iodoisoquinolin-1(2H)-ones are important building blocks for biologically and medicinally important compounds. The developed methodology was applied to the gram-scale synthesis of a key intermediate in the synthesis of the CRTH2 antagonist CRA-680.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.category: isoquinoline, you can also check out more blogs about34784-05-9
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H3564N – PubChem