Electric Literature of 41034-52-0, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 41034-52-0, 1,2,3,4-Tetrahydro-isoquinoline-1-carboxylic acid, introducing its new discovery.
The present invention relates to a crystal form of (R)-praziquantel and a preparation method and uses thereof. The X-ray diffraction pattern (CuKalpha radiation) of the crystal form of (R)-praziquantel at 25 C. shows the following diffraction peaks: 2-Theta=6.9±0.2, 8.3±0.2, 15.1±0.2, 17.4±0.2, 19.8±0.2, 21.9±0.2, 24.3±0.2 or d=12.74±0.20 ?, 10.61±0.20 ?, 5.87±0.20 ?, 5.09±0.20 ?, 4.48±0.20 ?, 4.06±0.20 ?, 3.66±0.20 ?. Compared to the existing crystal form of praziquantel, the crystal form of the present invention has better solubility, better drug efficacy and better pharmacokinetic characteristics. The preparation method of the present invention has the following advantages: good reproducibility, environmentally friendly, low cost, and able to operate at a normal pressure and temperature, and suitable for large-scale production.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 41034-52-0. In my other articles, you can also check out more blogs about 41034-52-0
Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem