Chemistry is traditionally divided into organic and inorganic chemistry. Application In Synthesis of Isoquinoline-1-carboxylic acid, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 486-73-7
Vanadium compounds can efficiently catalyse the oxidation of benzene to phenol with molecular oxygen. The reaction is truly catalytic only in the presence of a reducing agent able to recycle the oxidised catalyst. Among the reducing agents tested, ascorbate afforded the highest selectivity and reactivity to phenol. With other reductants, such as dithioalcohols, high selectivity (>96%) was obtained toward more oxidised products (i.e. hydroquinone). The reactions were performed in the two-phase system formed by mixing water/acetonitrile/benzene which allows a good separation between reactant and product. The reaction rate and product selectivity depend upon the type of ligand interacting with vanadium as well as upon the ascorbate/V molar ratio. ESR measurements confirmed that VIV species is rapidly formed in the reaction medium after the initial addition of VIII Cl3. Moreover, the observed initial induction period of benzene oxidation can be related to the formation of oligomeric VIV species, as assessed by ESR analysis, rather than to the slow formation of V-ascorbate complex.
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Reference：
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem