New learning discoveries about 1075-12-3

1075-12-3, As the paragraph descriping shows that 1075-12-3 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1075-12-3,7-Fluoroisoquinoline,as a common compound, the synthetic route is as follows.

7-Fluoroisoquinoline (45 g, 305 mmol) was dissolved in 350 mL of acetic acid and heated to 110 C. N-bromosuccinimide (NBS) (65 g, 367 mmol) was added in portions. After the addition, the reaction was carried out for 2 h, the solvent was removed, and the column (PE) was passed to obtain 20 g of the desired product (4-bromo-7-fluoro quinoline).

1075-12-3, As the paragraph descriping shows that 1075-12-3 is playing an increasingly important role.

Reference£º
Patent; Suzhou Kangrun Pharmaceutical Co., Ltd.; Zhao Xiaoying; Xu Weiliang; Xu Weizheng; (10 pag.)CN108314648; (2018); A;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem