So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Nfor, Emmanuel N.; Asobo, Peter F.; Nenwa, Justin; Nfor, Oswald N.; Njapba, Julius N.; Njong, Romanus N.; Offiong, Offiong E. researched the compound: 3,5-Di(pyridin-2-yl)-4H-1,2,4-triazol-4-amine( cas:1671-88-1 ).Synthetic Route of C12H10N6.They published the article 《Nickel (II) and iron (II) complexes with azole derivatives: synthesis, crystal structures and antifungal activities》 about this compound( cas:1671-88-1 ) in International Journal of Inorganic Chemistry. Keywords: preparation crystal structure nickel iron aminopyridyltriazole phenylpyrazoleylpyridine complex; antifungal activity nickel iron aminopyridyltriazole phenylpyrazoleylpyridine complex. We’ll tell you more about this compound (cas:1671-88-1).
Two new complexes of nickel(II) with 4-amino-3,5-bis(pyridyl)-1,2,4-triazole (abpt) and iron(II) with 2-(3-phenyl-1H-pyrazole-5-yl) pyridine (phpzpy) were synthesized and characterized by elemental anal. and IR spectroscopy. The prepared complexes are [Ni(abpt)2(OH2)2](ClO4)2 (1) and [Fe(phpzpy)2(NCS)2] (2). The crystal structures of the complexes were determined by single crystal x-ray diffraction techniques. In the nickel and iron complexes, the ligands are coordinated through nitrogen atoms in bidentate manner. The ligands and their resp. complexes were tested for their antifungal activity against Aspergillus niger, Aspergillus flavus and Candida albicans. The complexes showed enhanced activities against the tested organisms compared to the ligands.
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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem