So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Igawa, Kazunobu; Yoshihiro, Daisuke; Ichikawa, Nobumasa; Kokan, Naoto; Tomooka, Katsuhiko researched the compound: (3aR,8aR)-2,2-Dimethyl-4,4,6,8,8-pentaphenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine( cas:147700-62-7 ).SDS of cas: 147700-62-7.They published the article 《Catalytic enantioselective synthesis of alkenylhydrosilane》 about this compound( cas:147700-62-7 ) in Angewandte Chemie, International Edition. Keywords: silane chiral preparation desymmetrization dihydrosilane hydrosilylation alkyne; hydrosilylation asym alkyne taddol dioxaphosphepane platinum catalyst preparation alkenylsilane; absolute configuration alkenyl hydrosilane preparation asym hydrosilylation alkyne. We’ll tell you more about this compound (cas:147700-62-7).
Desymmetrization of secondary silanes R1R2SiH2 (R1, R2 = Ph, tBu; 2,6-Me2C6H3, Me; 2,6-Me2C6H3, Ph) by hydrosilylation of alkynes R3CCR3 (R3 = Me, Et, n-Pr) catalyzed by Pt(0) complexes with chiral taddol-based 1,3,2-dioxaphosphepane ligands I [6a-d, R = H, 4-MeO, 3,5-Me2, 3,5-(CF3)2] gave Si-chiral monoalkenylsilanes (E)-R1R2SiH(R3C:CHR3) (5) with moderate-to good yields and 30-86% ee. Depending on the aryl substitution of the catalyst, both (R)- and (S)-configuration of the silanes 5 were obtained. The absolute configuration of the prepared alkenyl hydrosilanes was established by sym. hydrosilylation of 1-butene with 5, and comparison with previously reported compounds prepared starting from chiral silanols.
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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem