Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-(5-Bromothiophen-2-yl)pyridine, is researched, Molecular C9H6BrNS, CAS is 123784-07-6, about Coupling of organotin reagents with aryl, acyl and heteroaryl halides. Part 2. Synthesis of thienylpyridine derivatives.Formula: C9H6BrNS.
Several new thienylpyridine derivatives were prepared by the Pd-catalyzed coupling of organotin compounds with aryl halides. Instances of homo-coupling of the aryl halides were described. For example, the coupling of 2-(tributylstannylmethyl)pyridine with 2-acetyl-5-bromothiophene gave 5,5′-diacetyl-2,2′-bithiophene and 2-(2-pyridylmethyl)-5-acetylthiophene.
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Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem