In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Selectivity Enhancement Arising from Interactions at the PI3K Unique Pocket, published in 2012, which mentions a compound: 42409-58-5, mainly applied to PI3K enzyme inhibitor imidazopyridine, COA of Formula: C6H7BrN2O.
A series of derivatives with various substituents (F, Me, Cl, OMe) at position C8 were designed, and extended mol. anal. was applied to these analogs to investigate the differences between the binding modes resulting from the occupation of the pocket by the newly introduced substituents.
There are many compounds similar to this compound(42409-58-5)COA of Formula: C6H7BrN2O. if you want to know more, you can check out my other articles. I hope it will help you,maybe you’ll find some useful information.
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem