Analyzing the synthesis route of 82827-09-6

The synthetic route of 82827-09-6 has been constantly updated, and we look forward to future research findings.

82827-09-6, 6-Bromoisoquinolin-1(2H)-one is a isoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

82827-09-6, Cesium carbonate (2.62 g), intermediate 1 (1.5 g) and (bromomethyl)cyclopropane (0.8 ml_) were stirred and heated at 50 0C for 4 hours. The mixture was allowed to cool then poured into water and extracted with ethyl acetate. The organic extracts were combined dried and evaporated under reduced pressure. The residue was triturated with ether and the sub-titled compound isolated by filtration (1.0g). MS: APCI(+ve) 277, 279 (M+H)+

The synthetic route of 82827-09-6 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2008/122765; (2008); A1;,
Isoquinoline – Wikipedia
Isoquinoline | C9H7N – PubChem