Recommanded Product: Diphenyl-2-pyridylphosphine. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Diphenyl-2-pyridylphosphine, is researched, Molecular C17H14NP, CAS is 37943-90-1, about Palladium-Catalyzed Domino Aminocarbonylation of Alkynols: Direct and Selective Synthesis of Itaconimides. Author is Ge, Yao; Ye, Fei; Yang, Ji; Spannenberg, Anke; Jackstell, Ralf; Beller, Matthias.
A selective synthesis of substituted itaconimdes I [R1 = Me, iPr, Ph, etc.; R2 = H, iPr, Bn, etc.; R1R2 = (CH2)3, (CH2)4, (CH2)5, etc.; R3 = Ph, 4-FC6H4, 2-HOC6H4, etc.] and II [Ar = Ph, 2-MeC6H4, 3-ClC6H4, 4-NCC6H4] by palladium-catalyzed aminocarbonylation of alkynols with anilines/aryl hydrazine was reported. Key to the success of this transformation was the use of a novel catalyst system involving ligand L11 and appropriate reaction conditions. The synthetic utility of the protocol was demonstrated in the synthesis of natural product 3-(propan-2-ylidene)pyrrolidine-2,5-dione with aminocarbonylation as the key step. Mechanistic studies and control experiments revealed the crucial role of the hydroxyl group in the substrate for the control of selectivity.
This compound(Diphenyl-2-pyridylphosphine)Recommanded Product: Diphenyl-2-pyridylphosphine was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.
Reference:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem