Isoquinoline can crystallizes in platelets that have a low solubility in water but dissolve well in ethanol, acetone, diethyl ether, carbon disulfide, and other common organic solvents. 1532-97-4, formula is C9H6BrN, Name is 4-Bromoisoquinoline. It is also soluble in dilute acids as the protonated derivative. Quality Control of 1532-97-4.
Leonard, David K.;Ryabchuk, Pavel;Anwar, Muhammad;Dastgir, Sarim;Junge, Kathrin;Beller, Matthias research published 《 A Convenient and Stable Heterogeneous Nickel Catalyst for Hydrodehalogenation of Aryl Halides Using Molecular Hydrogen》, the research content is summarized as follows. In this study, a nickel-based catalyst supported on titania (Ni-phen@TiO2-800) was prepared and used as a safe alternative to pyrophoric Raney-nickel. The catalyst was prepared in a straightforward fashion by deposition of nickel(II)/1,10-phenanthroline on titania, followed by pyrolysis. The catalytic material, which was characterized by SEM, TEM, XRD and XPS, consisted of nickel nanoparticles covered with N-doped carbon layers. By using design of experiments (DoE), this nanostructured catalyst was found to be proficient for the facile and selective hydrodehalogenation of a diverse range of substrates bearing C-I, C-Br, or C-Cl bonds afforded aromatic hydrocarbons R-H [R = 1-naphthyl, 4-H2NC6H4, 4-CO2MeC6H4, etc.] (>30 examples). The practicality of this catalyst system was demonstrated by the dehalogenation of environmentally hazardous and polyhalogenated substrates atrazine, tetrabromobisphenol A, tetrachlorobenzene and a polybrominated di-Ph ether (PBDE).
1532-97-4, 4-Bromoisoquinoline, also known as 4-Bromoisoquinoline, is a useful research compound. Its molecular formula is C9H6BrN and its molecular weight is 208.05 g/mol. The purity is usually 95%.
4-Bromoisoquinoline is an aryl halide that can be used in the cross-coupling reaction with other aryl halides. It has been shown to have anticancer activity and to inhibit the growth of tumour cell lines in vitro. This compound is also efficient for inhibiting leukemia cells. 4-Bromoisoquinoline has been shown to have an inhibitory effect on cancer cells through the inhibition of DNA synthesis and RNA transcription, as well as by inducing apoptosis. The mechanism of action may be due to its ability to bind to aromatic hydrocarbons and halides, which leads to thermodynamic changes and vibrational energy transfer., Quality Control of 1532-97-4
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem