Krapcho, A. Paul; Gallagher, Cynthia E.; Mammach, Abdelhakim; Ellis, Michael; Menta, Ernesto; Oliva, Ambrogio published the artcile< Synthesis of regioisomeric 6,9-(chlorofluoro)-substituted benzo[g]quinoline-5,10-diones, benzo[g]isoquinoline-5,10-diones and 6-chloro-9-fluorobenzo[g]quinoxaline-5,10-dione>, Computed Properties of 144511-13-7, the main research area is benzoquinoxalinedione preparation; benzoisoquinolinedione preparation; benzoquinolinedione preparation.
Treatment of difluoro or chloro fluoro-substituted benzyl bromides with zinc dust in THF leads to the corresponding benzylic zinc bromides. These organometallics on treatment with chlorosubstituted heterocyclic esters and mediated by nickel catalysis undergo couplings to yield dihalobenzyl substituted heterocyclic esters. The acids, prepared by hydrolysis of these esters, with treatment of fuming sulfuric acid undergo cyclizations and oxidations to yield the desired regioisomeric dihalo-substituted heterocyclic quinones.
Journal of Heterocyclic Chemistry published new progress about 144511-13-7. 144511-13-7 belongs to class isoquinoline, and the molecular formula is C13H5F2NO2, Computed Properties of 144511-13-7.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem