Molloy, John J.; Clohessy, Thomas A.; Irving, Craig; Anderson, Niall A.; Lloyd-Jones, Guy C.; Watson, Allan J. B. published the artcile< Chemoselective oxidation of aryl organoboron systems enabled by boronic acid-selective phase transfer>, Category: isoquinoline, the main research area is aryl organoboron compound chemoselective oxidation selective phase transfer; diboronic acid chemoselective oxidation selective phase transfer.
The authors report the direct chemoselective Brown-type oxidation of aryl organoboron systems containing two oxidizable B groups. Basic biphasic reaction conditions enable selective formation and phase transfer of a boronic acid trihydroxyboronate in the presence of boronic acid pinacol (BPin) esters, while avoiding speciation equilibrium Spectroscopic studies validate a base-promoted phase-selective discrimination of organoboron species. This phenomenon is general across a broad range of organoboron compounds and can also be used to invert conventional protecting group strategies, enabling chemoselective oxidation of BMIDA species over normally more reactive BPin substrates. The authors also demonstrate the selective oxidation of diboronic acid systems with chemoselectivity predictable a priori. The utility of this method is exemplified through the development of a chemoselective oxidative nucleophile coupling.
Chemical Science published new progress about Arylboronic acids Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), PROC (Process), RACT (Reactant or Reagent), PREP (Preparation). 3336-49-0 belongs to class isoquinoline, and the molecular formula is C9H7NO, Category: isoquinoline.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem