Hartung, Ryan E.; Wall, Mark C.; Lebreton, Sylvain; Smrcina, Martin; Patek, Marcel published the artcile< Selectivity of N- versus O-alkylation in Mitsunobu reactions with various quinolinols and isoquinolinols>, Quality Control of 3336-49-0, the main research area is quinolinol alc chemoselective Mitsunobu alkylation; isoquinolinol alc chemoselective Mitsunobu alkylation.
Reacting quinolinols and isoquinolinols under Mitsunobu conditions could give rise to N-alkylated products in addition to the normally desired O-alkylated structures. An in-depth study of how the solvent, reagent equivalent, position of the quinoline/isoquinoline nitrogen and type of reacting aliphatic alc. employed affected the ratio of N- vs. O-alkylation was described.
Heterocycles published new progress about Aliphatic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 3336-49-0 belongs to class isoquinoline, and the molecular formula is C9H7NO, Quality Control of 3336-49-0.
Referemce:
Isoquinoline – Wikipedia,
Isoquinoline | C9H7N – PubChem